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Biomedical subjects

X Morel

Publications and source records attributed to X Morel.

51 records · Page 3Linked to original sources

[Black hidrocystoma of the free margin of the eyelid].

A clinico-pathologic case of a black hidrocystoma of the left eyelid margin is reported in a 45-year-old female patient. Clinically, a black nodule was disclosed after eversion of the superior left lid. A surgical full thickness eyelid focal resection was performed to remove the cyst. Histopathology found a cyst covered with an epithelium with a double layer of cells and filled with a brownish granular content, typical of a black hidrocystoma.

Cytoplasmic Granules↗

[Histological changes related to scleral buckling for treatment of retinal detachment].

Treatment of retinal detachment frequently uses biocompatible materials to obtain scleral buckling. These materials are not devoid of consequences on surrounding tissues. In 3 eyes enucleated for failure of surgical treatment using scleral buckling materials, the changes prompted by episcleral implants could be observed. The sclera underwent both an inversion of its curvature and a reduction of its thickness under the material, as well as an encapsulation of the material was observed. While a silicone sponge was used in part to encircle one of these eyes, its capsular inner surface was regular and smooth. In contrast, hydrogel implants used in the three eyes showed a peripheral fragmentation prompting in two of them a typical foreign body giant cell granulomatous reaction. Changes in scleral curvature and scleral thinning were observed reflecting the consequences of the buckling procedure. The capsule formation occurred as it does for any nonabsorbable matérial implanted in tissues. Degradation and fragmentation of the hydrogel material suscitated a granuloma in response to fragments. These hydrogel specific changes should be recognized on microscopic examination of slides of either capsule or eyes previously in contact with this implanted material. They attested of the instability of hydrogel after implantation.

Aged↗

[Malignant melanoma on primary acquired conjunctival melanosis].

A primary acquired melanosis occurred in the right bulbar conjunctiva of a 65 year-old caucasian woman. After four years of steadiness, this lesion gave raise to a malignant conjunctival melanoma. The evolution remained under control three years after the end of the therapeutic procedures. Clinical and histopathological data are presented.

Aged↗

[Choroid melanoma associated with 2 other primary malignant lesions. Apropos of a case].

A case of choroidal melanoma associated to two other primitive malignancies is reported. The patient, a 65-year-old woman had an amelanotic choroidal tumor of her left eye. In her clinical history was found a previously treated kidney carcinoma eight years ago. A choroidal metastasis was therefore diagnosed. After radiation therapy, an initial regression was observed. Fifteen months later, the tumor grew again. Enucleation was performed, and histopathology concluded on choroidal malignant melanoma. Three years later, a mammal carcinoma was discovered and treated by mammectomy. Her ophthalmologic and general status remained normal until now. Amelanotic choroidal tumors are difficult to diagnose. Regular follow-up can lead to a change in the diagnosis. The occurrence of multiple cancers is still not fully understood.

Aged↗

[Biocompatibility of a porous alumina orbital implant. Preliminary results of an animal experiment].

PURPOSE: Evaluation of clinical tolerance and scanning electron microscopy study of the bio-colonisation of a porous ceramical alumina implant after evisceration of the rabbit. Preliminary results. METHODS: Sixteen white New Zealand rabbits were eviscerated. A porous hydroxyde alumina ball was implanted in the opened sclera and explanted 15, 30, and 90 days after implantation. Clinical tolerance was assessed and implant tissular ingrowth was analyzed by scanning electron microscopy. RESULTS: One infection was observed and there was no conjunctival breakdown. Fibrovascular ingrowth occurred as soon as 15 days after implantation, and was full at one month. CONCLUSION: Porous alumina implant orbital tissue tolerance and fast fibrovascular ingrowth in the rabbit socket suggest promising result in the human anophthalmic socket.

Aluminum Oxide↗

[Pseudotumor-like superficial conjunctival foreign body].

Pseudo-tumoral presentation of a superficial conjunctival foreign body. A 4-year-old girl was seen in consultation for an apparent conjunctival tumor of the inner canthus of the right eye. With a soft traction, the tumor was detached of the conjunctiva, as it represented in fact a foreign body. Histopathology helped to diagnose that the foreign body was made of textile fiber. Superficial conjunctival foreign bodies may sometimes appear difficult to identify primarily especially in children.

Child, Preschool↗

[Orbital schwannoma. Apropos of a case].

The orbital schwannoma or neurilemoma is a rare tumor. We report herein the single case of a 51-year-old woman presenting an inferior extraconal orbital schwannoma and multiple sclerosis. Surgical treatment with complete excision allowed healing.

Blepharoptosis↗

[Mooren's ulcer following combined extracapsular crystalline lens extraction and trabeculectomy].

We report the case of a 70-year-old patient who presented with Mooren's ulcer in her right eye following extracapsular cataract extraction combined with trabeculectomy. She was successfully treated by a sclerocorneal graft combined with a large conjunctival resection. Clinical and histological features, and therapeutic outcomes are discussed and compared to previously published data.

Aged↗

[Ring recurrence of ciliary body melanoma after proton-beam therapy].

A malignant ciliary body melanoma was treated by proton-beam irradiation. Ring-shaped recurrence with extraocular extension appeared thirty-six months later and required enucleation. Histologic study revealed a predominant epithelioid cell type tumor, flattened in previously treated area. Proton-beam irradiation efficiency depends on clinical evaluation, which remains questioned in ciliary body locations where circumferential extension could be misevaluated.

Aged↗

[Differential diagnosis of conjunctival melanoma: exteriorized uveal melanoma].

Four years after unexplained left eye visual loss and 15 days after surgical procedure on the other eye, a 93-year-old female developed a pigmented left conjunctival lesion. Ultrasound examination demonstrated this lesion to be in fact an extraocular extension of uveal melanoma. The patient was treated by external radiotherapy after expanded enucleation.

Aged↗

[Isolated ocular melanosis. Apropos of a case].

A case of an eighteen month child with ocular melanocytosis is reported. The authors describe clinicopathological features of the affection. Ocular melanocytosis is a neural crest disorder more frequently found in pigmented populations. Differential diagnosis are naevus of Ota, blue sclera disease and scleritis. The risk of malignant degeneration especially in caucasian people explain that patient should be followed-up at regular intervals.

Black People↗

[Caruncular melanoma. Apropos of clinical case].

The clinicopathologic case of a 69-year-old-female patient with a big caruncular melanoma is reported. Tumor was excised surgically and underwent external conventional radiation therapy with no recurrence two years later. Histopathology endorsed the clinical diagnosis and thickness of the tumor measured 5.5 mm. The bad prognosis of the caruncular location was reinforced by the tumor thickness. A better knowledge of conjunctival melanomas characteristics might allow an earlier diagnosis and a better prognosis as irradiation following surgical treatment appears efficient on unifocal limited melanomas.

Aged↗

[Pigmented basal cell carcinoma of the eyelid. Apropos of a clinical case].

A clinico-pathologic case of a 83-year-old female patient with a deeply pigmented inferior lid tumor is reported. The histopathological study of the tumor demonstrated a pigmented basal cell carcinoma. Numerous different tumors may affect the eyelids, melanocytic or not in nature. True melanomas are infrequent compared with the numerous other pigmented tumors, which always need a histological analysis.

Aged↗

[Chronic pseudo-tumor inflammation of the eyelid induced by reaction to a non-resorbable suture. Apropos of an anatomo-clinical case].

A clinico-pathological observation of one case of nonabsorbable sutures in the superior right eyelid was reported in a 79-year-old patient. The main clinical finding was a painful reddish eyelid. Surgical excision was performed. Histopathological analysis found a non-granulomatous chronic inflammatory reaction surrounding suture fragments. Uncommon in eyelids, such an inflammatory reaction against sutures attests the likely intolerance to the suture material.

Aged↗