Biomedical subjects

Xiang-yang Liu

Publications and source records attributed to Xiang-yang Liu.

6 recordsLinked to original sources

PubMed2006

[Prognostic significance of micropapillary pattern in pulmonary adenocarcinoma].

OBJECTIVE: To evaluate the prognostic significance of micropapillary pattern (MPP) in adenocarcinoma of lung. METHODS: Ninety-one consecutively excised cases of pulmonary adenocarcinoma, including follow-up data, were retrospectively studied. These tumors were divided into 2 major groups: those with MPP and those without MPP. The former was further subdivided according to extent of the micropapillary component, as follows: MPP + (constituting 1% to 10% of the tumor), MPP ++ (constituting 11% to 30% of the tumor) and MPP +++ (constituting more than 30% of the tumor). RESULTS: The overall 5-year survival rate was 64.8%. The 5-year survival rates were 88.9% for stage I tumors, 46.2% for stage II tumors, and 23.8% for stage III tumor respectively (P = 0.000). The extent of micropapillary component showed no correlation with tumor stage, size and 5-year survival rate (P = 0.065, 0.358 and 0.206, respectively). On the other hand, the 5-year survival rate was 41.5% for patients in the MPP-positive group (number = 41) and 84.0% for patients in the MPP-negative group (number = 50). The percentage of nodal metastasis in MPP-positive group was also higher than that in MPP-negative group (P = 0.000). In pulmonary adenocarcinoma, this characteristic histology correlated with tumor stage and size, but not with patient's gender and smoking history. Within the same stage, the 5-year survival rates of MPP-positive and MPP-negative groups were as follows: for stage I, 78.6% versus 92.6% (P = 0.1548), for stage II, 30.0% versus 100% (P = 0.0598), and for stage III, 17.7% versus 28.6% (P = 0.4045). CONCLUSIONS: MPP in primary pulmonary adenocarcinoma, even when only constituting a minor component, predicts an aggressive clinical behavior and is associated with poor prognosis. Although it may not be an independent prognostic factor, presence of this histologic pattern should alert clinicians for more active treatment and closer follow up.

Adenocarcinoma↗

PubMed2006

[Observation on therapeutic effect of acupoint catgut embedding therapy on premenstrual syndrome].

OBJECTIVE: To compare clinical therapeutic effects of acupoint catgut embedding therapy and medicine on premenstrual syndrome, so as to search for the best method for this disease. METHODS: Eighty-eight cases were randomly divided into a catgut embedding group and a medication group. The catgut embedding group were treated with main points, Neiguan (PC 6), Sanyinjiso (SP 6), Danzhong (CV 17), Guanyuan (CV 4), Taichong (LR 3), and aduvant points, Back-shu, and the medicine group with oral administration of fluoxetine. After treatment of 3 months, their therapeutic effects were compared. RESULTS: The therapeutic effect of the catgut embedding group was better than that of the medication group with a very statistically significant difference (P < 0.005). CONCLUSION: Acupoint catgut embedding is a better therapy for premenstrual syndrome.

Acupuncture Points↗

PubMed2005

[Diagnosis and surgical treatment of metachronous second primary lung cancer].

OBJECTIVE: To review the experience of the diagnosis, surgical treatment and prognosis of metachronous second primary lung cancers. METHODS: Between January 1983 and April 2004, 32 patients with metachronous second primary lung cancers were operated in our department. Clinical data of all these patients were reviewed retrospectively. RESULTS: The initial procedures for their first primary lung cancers were lobectomy or pneumonectomy. Lobectomy or completion pneumonectomy for the second primary lung cancers were performed in 17 cases, limited pulmonary resection was done in 14 cases and exploration was in 1 case. The postoperative morbidity and mortality were 12% (4/32) and 3% (1/32), respectively. The 1-, 3-, and 5-year survival rate after second operation were 66% (19/29), 32% (9/28) and 19% (4/21), respectively. CONCLUSIONS: The incidence of metachronous second primary lung cancers has been increasing gradually during recent years. The closely follow-up for patients undergoing resection for their first primary lung cancers is most important factor for improvement of the diagnosis of metachronous second primary lung cancers. Limited resection and incomplete lymph node dissection might be the factors contributing to the poor prognosis.

Adult↗

PubMed2005

[Development of a prototype of space vegetable-cultivating facility for ground-based experiments].

OBJECTIVE: To develop a ground-based experimental prototype of space vegetable-cultivating facility (GEPSVF), so as to solve the main key techniques related to higher plant cultivation in space environmental conditions, and to further lay a foundation for future development and application of the prototype of space vegetable-growing facility. METHOD: Based on detailed demonstration and design of technique plan, the blueprint design and machining of components, whole facility installment, debugging, trial operations and verification experiments were done. RESULT: The parameters in the growing chamber such as temperature, relative humidity, wind velocity, total pressure, O2 partial pressure, CO2 partial pressure and water content of the growing media were totally and effectively controlled; the light source was electronic fluorescent lamp; the average vegetable-producing output reached 60 g (fresh weight) d-1. CONCLUSION: The prototype could operate stably; its actual performance indexes achieved the expected ones basically; some of its operating principles can adapt to space microgravity condition. Therefore, the prototype is a good beginning for future development of space vegetable-producing facilities.

Atmospheric Pressure↗

PubMed2005

[Altered expression of the HSD17B4 gene in esophageal squamous cell carcinoma and loss of heterozygosity analysis].

OBJECTIVE: To investigate the alteration of the gene HSD17B4 in esophageal squamous cell carcinoma and its potential significance. METHODS: The mRNA expression and loss of heterozygosity (LOH) of HSD17B4 in 40 primary esophageal tumors were detected by reverse transcriptase-polymerase chain reaction (RT-PCR) and microsatellite analysis with the intragenic marker D5S1384 of the gene. RESULTS: The frequencies of allelic loss of D5S1384 and the rate of down-regulation of gene HSD17B4 were 46.2% and 62.5%, respectively. CONCLUSION: HSD17B4 may be a candidate tumor suppressor gene associated with esophageal squamous cell carcinoma.

17-Hydroxysteroid Dehydrogenases↗

PubMed2005

[C2H4 reducing facility for controlled ecological life support system].

OBJECTIVE: To develop an experimental facility for reducing C2H4 produced by plants' growing in the controlled ecological life support system (CELSS). METHOD: Based on technical parameters and performance requirements, project planning, design drawing, fabrication, and debug were conducted. Then, an experimental test for reducing C2H4 was done by measuring the content of C2H4 in gases between the inlet and the outlet of the facility. Its C2H4 decomposing capacity was evaluated. RESULT: The facility worked well, and the parameters, such as energy consumption, and volume, met the design requirements. The experimental test results demonstrated that the content of C2H4 was reduced from 0.034 mg/kg to below 0.010 mg/kg, under the condition that the relative humidity and velocity of flow of the inlet-gas was 20% and 1.0-3.0 L/min respectively, and power of the lamp was 48 W. Considering the composition and the content of the gas in the outlet of the facility, there was no harmful product to the plants, except CO2 and H2O. CONCLUSION: The facility has reasonable technical indices, and smooth and dependable performances. It can be used as a facility for decomposing C2H4 in plants growing system in CELSS.

Air Conditioning↗