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Biomedical subjects

Xiao-Xia Li

Publications and source records attributed to Xiao-Xia Li.

3 recordsLinked to original sources

[Study on dynamic spectrum and its frequency domain extracting method].

For non-invasive blood components detection using near-infrared spectrum, eliminating the influence of the individual difference is very important. In the non-invasive component measurement, the individual discrepancy refers to the difference of personal feature in measured tissues except the pulsatile component of artery blood, including hairs, horny layer, subcutaneous tissue, muscle, skeleton etc. It is declared that the individual discrepancy is different from the personal feature; it is an important factor blocking the practice of the technology. In the present article, a new method of detecting blood components is presented, which is based on the principle of photoplethysmography and Fourier transform. With this method, the influence of individual difference caused by skin and other tissues can be mostly eliminated, and the absorbance of artery blood could be obtained. The concept of the frequency domain extracting method was presented. The experiment was done and the dynamic spectrum which only evaluates the pulsatile part of the entire optical signal was obtained. The advantage of dynamic spectrum with frequency domain extracting method is analyzed. The result shows that the method can be realized and has many advantages.

English Abstract↗

[Accuracy analysis of pulse oximetry based on dynamic spectroscopy].

The pulse oximeter used to measure patients oxygen saturation non-invasively and continuously, has numerous applications in clinic care. The pulse oximetry measurement combines two basic methods, spectrophotometry and photoplethysmography (PPG). The red light and the infrared light are exposed to the ear lobe, finger or other tissue with fluctuation of artery blood, and then detected. The amplitude ratio of the photoplethysmography waveform of red light and infrared light varies with the oxygen saturation of blood. The measuring principle of the pulse oximeter is based on traditional test method, its accuracy is not gratifying due to various factors influencing the measurement result, such as the principle, measuring condition, and individual discrepancy. In the present paper a new pulse oximetry based on dynamic spectroscopy is introduced, It can promote the accuracy of the pulse oximeter evidently. The dynamic spectroscopy method is able to eliminate the interference of individual discrepancy and measuring condition in principle. This new method can eliminate the measurement error of pulse oximetry theoretically.

Humans↗

Effect of human neural progenitor cells on injured spinal cord.

OBJECTIVE: To study whether human neural progenitor cells can differentiate into neural cells in vivo and improve the recovery of injured spinal cord in rats. METHODS: Human neural progenitor cells were transplanted into the injured spinal cord and the functional recovery of the rats with spinal cord contusion injury was evaluated with Basso-Beattie-Bresnahan (BBB) locomotor scale and motor evoked potentials. Additionally, the differentiation of human neural progenitor cells was shown by immunocytochemistry. RESULTS: Human neural progenitor cells developed into functional cells in the injured spinal cord and improved the recovery of injured spinal cord in both locomotor scores and electrophysiological parameters in rats. CONCLUSIONS: Human neural progenitor cells can treat injured spinal cord, which may provide a new cell source for research of clinical application.

Journal Article↗