Biomedical subjects

Xin-Jie Mao

Publications and source records attributed to Xin-Jie Mao.

2 recordsLinked to original sources

PubMed2004

[Effects after orthokeratology on corneal topography and monochromic wavefront aberration].

OBJECTIVE: To assess the corneal topography and monochromatic wavefront aberration among subjects using orthokeratology. Changes of ocular optical quality and related visual functions induced by corneal topography were studied. METHODS: Twenty-five young myopic subjects (50 eyes) were recruited with myopia from -1.75 approximately -4.75 D. Orthokeratology lens were fitted at the initial visit with overnight wear program. Subjective refraction, corrective visual acuity, corneal topography and slit lamp examination were performed before and 1 day, 1 week, 2 weeks, 4 weeks, 8 weeks and 12 weeks after the fitting of orthokeratology lens. The monochromic wavefront aberration was measured in initial visit and after 12 weeks. RESULT: The best corrected visual acuity was reduced significantly from (-0.0628 +/- 0.0286) LogMAR (before orthokeratology) to -0.0120 +/- 0.0318 (12 weeks after orthokeratology) (F = 17.821, P < 0.001). Root-mean-square (RMS) of wavefront aberration increased significantly from (0.5766 +/- 0.4771) micro m (before orthokeratology) to (1.3731 +/- 0.8039) micro m (12 weeks after orthokeratology) (F = 36.513, P < 0.001). RMS of Zernike function of each order was increased as well. The rate of eccentric in posterior surface of corneal increased significantly after the using of orthokeratology lens. CONCLUSIONS: Orthokeratology is one of the effective methods for reducing myopia temporarily. However, the best corrected visual acuity is decreased after using of orthokeratology. The increase of aberration induced by orthokeratology can be the cause of reduction of ocular optical quality.

Adolescent↗

PubMed2003

[Study of corrected visual performance and vision quality].

OBJECTIVE: The present study was designed to examine the visual acuity (VA) and contrast sensitivity function (CSF) under three refractive correction methods, the visual performance and vision quality under different correction methods were compared and analyzed. METHODS: Twenty three college students with myopia (41 eyes, myopia range: -1.25 D approximately 9.25 D; astigmatism < 0.50 D) were enrolled and fully corrected by three different methods: 1) spectacles with resin lens material (SP); 2) soft contact lens (SCL); 3) rigid gas-permeable lens (RGP). The distant and near LogMar VA and CSF were examined. To avoid the subjective bias, the correction procedure was randomly selected and the VA chart and CSF chart used had the same pattern but different letters' organization or directions. RESULTS: The best corrected distant VA was significantly higher in RGP wearing eyes than those in the Soft-CL and SP wearing eyes (P < 0.01 and P < 0.05, respectively). No statistically significant difference was detected between the SP and SCL wearing eyes. There was no significant difference in the near VA among these three conditions, although the near VA in RGP group was slightly better than that in the SCL condition. There was no significant difference in CSF value at low spatial frequencies (1.5 cpd and 3 cpd) among these three conditions. However, at middle and high spatial frequencies (6 cpd, 12 cpd and 18 cpd), the RGP curve was the highest and followed by the SCL and SP curves. CONCLUSION: RGP correction offers the best visual acuity quality for myopia subjects. The CSF assessment can be used as an indirect method to evaluate the quality of corrected retinal image.

Adult↗