Biomedical subjects

Y Aslan

Publications and source records attributed to Y Aslan.

34 records · Page 2Linked to original sources

PubMed1991

Measuring pressures under maxillary complete dentures during swallowing at various occlusal vertical dimensions. Part I: A new hydraulic pressure measuring system.

This study presents a "closed" hydraulic pressure measuring system capable of measuring pressures at the denture base-mucosal surface interface. Two pressure receptors are made in the denture base of a maxillary denture. The receptors are covered with a flexible membrane and are connected to pressure transducers by means of polyethylene tubes. The transducers convert the hydraulic pressures coming from the receptors to electrical signals. A polygraph is used to amplify and record the electrical signals. It is assumed that complete contact can be obtained between mucosa and the flexible membranes, which is the advantage of this system.

Calibration↗

PubMed1991

Measuring pressures under maxillary complete dentures during swallowing at various occlusal vertical dimensions. Part II: Swallowing pressures.

The swallowing pressures of seven edentulous patients were measured at seven different occlusal vertical dimensions. In addition, the projection surfaces of the maxillary dentures were measured and the forces on the maxillary denture-bearing surfaces were calculated. The swallowing pressures were measured from the maxillary denture base-mucosal surface interface by means of a "closed" hydraulic system described in Part I. The mean values of swallowing pressures increased from 7.95 +/- 2.25 to 10.18 +/- 3.42 kPa as the occlusal vertical dimension increased, and then decreased to 8.38 +/- 3.55 kPa at the highest occlusal vertical dimension. The results of a two-way analysis of variance showed significant differences of swallowing pressures between patients (p less than 0.001) and between different occlusal vertical dimensions (p less than 0.001). The projection surfaces of maxillary denture bases were measured and ranged from 21.65 to 27.78 cm2. The forces exerted on these surfaces during swallowing were also calculated and ranged from 12.5 to 47.7 N.

Adult↗

PubMed1990

Monopoly coating on acrylic resin surfaces: a bacteriologic study.

In an open bulb of a buccal flange obturator, it is almost impossible to polish the inner surface of the bulb. Because it cannot be cleaned easily, oral and nasal secretions lead to odors. To obtain a smoother surface, it is suggested that monopoly be painted on the unpolished surface of the open bulb. In this study, the effect of a monopoly coating on bacteria retention and washability of acrylic resin surfaces was investigated. Coated and uncoated acrylic resin samples were prepared and both were contaminated with Escherichia coli. After standard washing, the remaining viable E. coli colonies were counted. The statistical results showed that the difference in the number of E. coli colonies between coated and uncoated groups was highly significant (p less than 0.001). It was suggested that monopoly should be applied to the acrylic resin surfaces where mechanical polishing cannot be done.

Acrylic Resins↗

PubMed1990

[Speech and prostheses for congenital cleft palate patients in adulthood].

The surgical treatment should be preferred for cleft palate patients in childhood. However, a prosthesis is favorable for some adult patients. The construction of prostheses are rather complicated for patients who require pharyngeal speech aid in addition to anterior prosthesis. Sound prosthodontic rules are valid in designing a speech aid prostheses. Often stability and retention increase is required for these prostheses. Furthermore, the velar and the pharyngeal sections should not interfere with the muscular activity of pharynx and/or tongue movements during speech and deglutition. This article describes the prosthodontic habilitation of congenital cleft palate patients by means of pharyngeal speech aid prosthesis.

Adult↗

PubMed1982

Prosthodontic rehabilitation for glossectomy patients.

Patients with oral carcinomas often have resection of the tongue, the floor of the mouth, or the bone of the mandible. Postoperatively, these patients encounter chewing, swallowing, and speech problems. Oral rehabilitation through prosthetic management can aid in alleviating these problems. Designs of the prosthesis vary according to patient needs. A "snap-on" tongue prosthesis or palatal augmentation prosthesis can be constructed. Total glossectomy patients require prosthetic intervention on a mandibular framework. Partial glossectomy patients require prosthetic augmentation on a maxillary framework. Through prosthetic management of this type, articulation and resonance are improved, food is more easily directed into the esophagus, tissues are protected and socialization is enhanced through improved appearance.

Deglutition↗

PubMedDate not supplied

Multiple intracranial hemorrhages at the time of a transiently prolonged activated partial thromboplastin time in an infant with congenital factor VII deficiency.

Factor VII (FVII) deficiency is a rare autosomal recessive hereditary disorder characterized by a normal partial thromboplastin time and a prolonged prothrombin time. For definitive diagnosis, the specific FVII level should be investigated. We report on a 7-month-old boy with congenital FVII deficiency suffering from convulsions and intracerebral hemorrhage. Hematologic tests revealed prolonged prothrombin time associated with a decreased FVII level of 1.7%. Computerized tomography of the brain revealed multifocal hemorrhagic lesions. To our knowledge, multifocal intracranial hemorrhages at the time of a transiently prolonged partial thromboplastin time of unknown origin in a child with congenital FVII deficiency of about 2% has not been reported so far.

Cerebral Hemorrhage↗

PubMedDate not supplied

Congenital primary hypoparathyroidism presented with extensive cutaneous and subcutaneous calcifications.

Congenital primary hypoparathyroidism is very rare in infancy. It may be isolated or associated with other developmental defects, arising from the third and fourth pharyngeal pouches such as DiGeorge syndrome. Initial symptom of isolated primary hypoparathyroidism in an infant is usually generalized convulsion due to hypocalcemia. However, the clinical spectrum of DiGeorge's anomaly is highly variable. We report a two-hour-old neonate with congenital hypoparathyroidism presenting with extensive cutaneous and subcutaneous calcifications. To our knowledge, extensive calcification of the skin and subcutaneous tissue as a presenting feature of congenital primary hypoparathyroidism in an infant is reported for the first time.

Calcinosis↗

PubMedDate not supplied

Gastric perforation presenting as bilateral scrotal pneumatoceles.

Although processus vaginalis is patent in the majority of newborn infants, the expression of an intraabdominal pathology such as gastrointestinal perforation or bleeding in the scrotum is very rare. In a large percentage of neonates with the gastrointestinal perforation, pneumoperitoneum is absent. In any case, it may not be detected in early radiographs. We report a newborn baby who presented with bilateral scrotal pneumatoceles as a first sign of pneumoperitoneum due to gastric perforation. Plain x-ray of the abdomen was normal except for pneumoscrotum, but contrast study revealed gastric perforation.

Diagnosis, Differential↗

PubMedDate not supplied

Various clinical aspects of DIDMOAD (Wolfram) syndrome.

The association of juvenile diabetes mellitus (DM), diabetes insipidus (DI), optic atrophy (OA) and sensorineural deafness (D) is known as DIDMOAD or Wolfram syndrome. Aside from these four cardinal features, a wide variety of abnormalities of the nervous system, urinary tract and endocrine glands have been described in this syndrome. In this report, the clinical features of six patients with DIDMOAD syndrome are presented. All six patients had DM. Five of the six patients had DI, five OA and five displayed abnormal audiogram findings. In addition, two had goiter, two delayed puberty, one seizure and one mental retardation with depression attacks. Urinary tract dilatation was recorded in five patients. Four patients developed typical complications of DM. One of them had overt nephropathy and arthropathy despite the short duration of DM. In addition, this patient had diabetic retinopathy, which is considered to be rare in this syndrome.

Adolescent↗

PubMedDate not supplied

The role of high-dose methylprednisolone therapy in paroxysmal nocturnal hemoglobinuria.

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder characterized by intermittent hemolytic anemia. High-dose methylprednisolone (HDMP) was administered in two patients, eight- and 16-year-old females, with PNH. This drug produced a dramatic improvement in the hemoglobin level, leukocyte and platelet counts. No side effect was observed in either patient during the treatment period. The patients were followed up on an outpatient basis for six and 16 months. In conclusion, HDMP therapy for PNH appears to be more effective and safe than previously reported therapies.

Adolescent↗

PubMedDate not supplied

Asymmetric crying facies: an index of other malformations.

Congenital hypoplasia or absence of the depressor anguli oris muscle is a minor congenital anomaly causing asymmetrical crying facies (ACF). The interesting aspect of this abnormality lies in the frequently associated abnormalities. Cardiac, urogenital, musculoskeletal, respiratory and cervicofacial defects have been described in cases with ACF. Therefore it is suggested that ACF can be used as an index of other congenital malformations. We report three cases with ACF who had varied congenital anormalites.

Abnormalities, Multiple↗

PubMedDate not supplied

Langerhans cell histiocytosis associated with recurrent pneumothorax: a case report.

Pulmonary involvement of Langerhans cell histiocytosis (LCH) is an uncommon but important cause of pulmonary fibrosis and honeycombing in young adults. Rarely, pulmonary LCH may be complicated by spontaneous pneumothorax. It may be isolated or associated with multiple organ involvement. We describe here a case of LCH with diabetes insipidus, skin lesions and pulmonary involvement in a 15-year-old boy. The case was complicated by four episodes of spontaneous pneumothorax with typical radiologic findings of pulmonary LCH. His presentation, radiologic findings, treatment and clinical course during three-years of follow-up are discussed.

Adolescent↗

PubMedDate not supplied

Serum granulocyte-macrophage colony-stimulating factor and interleukin-1 levels in patients with repeated and non-repeated pulmonary infections.

Granulocyte-macrophage colony-stimulating factor (GM-CSF) has a stimulating effect on erythroid, megakaryocytic and granulocyte-macrophage progenitors. Activated T lymphocytes, monocytes, fibroblasts and endothelial cells release GM-CSF after stimulation by endotoxin and cytokines such as interleukin-1 (IL-1) and tumor necrosis factor. IL-1 is also released in response to bacterial infections and inflammation by phagocytic mononuclear cells. GM-CSF and IL-1 levels were examined in 10 patients with recurrent pulmonary infection (repeaters) and in 10 patients with acute pulmonary infection (non-repeaters) in the acute and recovery periods of infection. The mean serum GM-CSF and IL-1 levels of non-repeaters were significantly higher than those of repeaters in the acute period of infection (p < 0.002), but the same parameters of both groups were not different in the recovery period (p > 0.05). In addition, both the serum GM-CSF and IL-1 levels of repeaters and non-repeaters in the acute period of infection were higher than those in the recovery period (p < 0.05). There was a positive correlation between serum IL-1 and GM-CSF levels in non-repeaters (r = 0.746, p = 0.013), but no significant correlation between the same parameters in repeaters (r = 0.395, p = 0.259). In this study, we could not explain why the serum GM-CSF and IL-1 levels in repeaters did not increase as they did in non-repeaters; moreover, there was no significant correlation between serum IL-1 and GM-CSF levels in repeaters during the acute period of infection. These findings may be due to microenvironmental factors in bone marrow and/or other factors.

Acute Disease↗

PubMedDate not supplied

Intracerebral hemorrhage: a rare late manifestation of vitamin-K deficiency in a breastfed infant. A case report.

Late hemorrhagic disease of the newborn (HDN) is a rare complication of vitamin-K deficiency and is especially associated with intracranial hemorrhage. It may also occur in infants who received vitamin-K prophylaxis at birth. Here, we reported a case of late HDN with frontal lobe hemorrhage due to vitamin-K deficiency. This form of intracranial hemorrhage of late HDN has been reported in the literature very rarely. We conclude that the efficiency of single-dose vitamin-K prophylaxis should be revaluated.

Age Factors↗

PubMedDate not supplied

Absorption of iron from grape-molasses and ferrous sulfate: a comparative study in normal subjects and subjects with iron deficiency anemia.

We compared the absorption of iron from grape molasses (GM) and ferrous sulfate (FS) using the post-absorptive serum iron increase method (non-radioactive). The study involved 56 subjects, aged 6-36 months. Group I consisted of 30 subjects with iron deficiency anemia (IDA) and group II, 26 non-anemic subjects. Each group was subdivided randomly into two equal subgroups to be given either GM or FS. The absorption of the iron from GM was monitored in 15 infants with IDA and in 13 non-anemic infants, and the absorption of iron from FS was tested in the rest of the subjects in each group. In those infants in each group given GM or FS, there was no significant difference in before-test values for serum iron (SI) and total iron binding capacity (TIBC) (p > 0.05). In the group with IDA, the mean after-test SI value in FS-given infants was higher and the mean TIBC value lower than those of GM-given infants (p < 0.05). However, in the non-anemic group, there was no significant difference in the mean after-test SI and TIBC values in either GM- or FS-given infants (p > 0.05). The mean increase of serum iron in GM-given infants with IDA was 27.0 +/- 13.4 micrograms/ dl and in FS-given infants, 60.6 +/- 17.0 micrograms/dl (p < 0.05). In the non-anemic group, the mean increase of serum iron of GM-given infants was 23.0 +/- 4.3 micrograms/dl, and that of FS-given infants, 23.8 +/- 10.0 micrograms/dl (p > 0.05). We determined that in non-anemic subjects, the absorption of iron from GM was comparable to that from FS. Furthermore, we believe that grape molasses is an effective iron source in preventing iron deficiency anemia in infancy.

Absorption↗

PubMedDate not supplied

Occult pneumococcal septicemia and pneumococcal pneumonia complicating pneumatoceles in a previously healthy child.

Fulminating pneumococcal septicemia without an obvious focus of infection is very rare in previously immunocompetent children older than two years. Furthermore, pneumatocele formation in pneumococcal pneumonia is uncommon. The majority of pneumatoceles are self-limited and disappear spontaneously. Here, we report a six-year-old healthy child with occult pneumococcal septicemia and pneumococcal pneumonia secondary to septicemia. Giant pneumatoceles causing respiratory insufficiency formed secondary to the pneumococcal pneumonia and were aspirated via needle under fluoroscopic guidance.

Child↗