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Y Basaran

Publications and source records attributed to Y Basaran.

10 recordsLinked to original sources
PubMed2001

Paravalvular leakage after mitral valve replacement: is left atrial enlargement an additional indication for reoperation?

BACKGROUND AND AIM OF THE STUDY: Prostheses used to treat heart valve disease improve patient survival, but have certain disadvantages. Paravalvular leakage (PVL) is a rare complication after mitral valve replacement (MVR), and can impair cardiac function and reduce the patient's functional capacity, depending on the degree of periprosthetic regurgitation. METHODS: Between 1985 and July 1999, 2,502 patients underwent MVR with or without concomitant cardiac procedures. Of these patients, 33 (18 males, 15 females; mean age 39.8+/-15.3 years; range: 12-62 years) had PVL of differing degree. The interval between MVR and observation of PVL was 30.5+/-31.5 months (range: 1-126 months), and the period after diagnosis was 22.6+/-31.5 months (range: 2-114 months). Fourteen patients (42.4%) underwent reoperation (RO group), and 19 (57.6%) were followed medically (ME group). Indications for reoperation were reduction of functional capacity, echocardiographically proven serious mitral regurgitation, and hemolysis. RESULTS: Reoperative mortality was 3.0% (1/33), and late mortality 3.1% (1/32) for all patients. Cumulative survival after PVL was 90.2+/-6.7% at both five and ten years. Annular calcification (33.0%) and infective endocarditis (18.2%) were important predictive factors for development of PVL. Only one patient required second re-do surgery. Univariate and forward stepwise logistic regression analyses showed that there was no predictor for the development of severe PVL requiring a second reoperation. No difference was observed between left ventricular dimensions before and after periprosthetic regurgitation. The only significant finding between groups was an increase in left atrial diameter in RO patients after the development of PVL (p <0.05). CONCLUSION: Among patients undergoing MVR there are no clinical features to distinguish who will develop severe PVL during follow up. If PVL reduces the patient's functional capacity or causes serious hemolysis, or if severe PVL is evaluated echocardiographically, then reoperation must be performed. Mild or moderate mitral regurgitation without impairment of functional capacity may be followed medically. In asymptomatic patients, enlargement (>5%) of the left atrial diameter following development of moderate PVL may be a valuable criterion for deciding when to reoperate.

Adolescent↗
PubMed2000

Cardiac thrombosis in a patient with Behçet's disease: two years follow-up.

A 28-year-old man with Behçet's disease was presented with cardiac symptoms in addition to previous complaints of oral and genital ulcers. A diagnosis of thrombosis was made and patient began to receive anticoagulant and immunosuppressive therapy and was followed by echocardiographic examination. Despite medical therapy, thrombosis recurred. Surgical excision was performed and histological findings were consistent with organizing thrombus. Nature of cardiac involvement and review of literature on cardiac thrombosis in Behçet's disease was discussed.

Adult↗
PubMed2000

Left ventricular inflow normal or pseudonormal. A new echocardiographic method: diastolic change of left atrial diameter.

UNLABELLED: Mitral flow Doppler study has been used to evaluate left ventricle (LV) diastolic function. Through its use, greater A wave than E wave, pseudonormal pattern, and restrictive pattern were observed progressively in patients with more LV diastolic dysfunction. Differentiation of normal or pseudonormal mitral flow is very important. In this study, left atrium (LA) diameter change during diastole was used as a new method for the differentiation of normal and pseudonormal mitral flow. METHOD: Sixty-eight patients (30 men, 38 women; mean age 53 +/- 13 years) with echocardiographically determined diastolic dysfunction and 60 healthy volunteers (36 men, 24 women; mean age 49 +/- 12 years) were included in the study. Mitral flow E/A ratio, isovolumetric relaxation time (IVRT), and deceleration time (DT) of E wave were used for determination of the diastolic dysfunction. Thirty of 68 diastolic dysfunction patients had A>E wave, 20 had pseudonormal mitral flow pattern, and 18 had restrictive mitral flow pattern. Left parasternal long-axis echocardiographic window was used for the measurement of LA diameter. Left atrium emptying fraction (LAEF) was defined as ratio of end-diastolic LA diameter to end-systolic diameter. RESULTS: LAEF was found 0.69 +/- 0.01 (mean +/- SE) in the control group, 0.76 +/- 0.01 in the A>E group (P < 0.05, control vs A > E group), 0.83 +/- 0. 05 in the pseudonormal pattern group (P < 0.05, control vs pseudonormal pattern group), and 0.87 +/- 0.01 in the restrictive pattern group (P < 0.001, control vs restrictive pattern group). CONCLUSION: (1) LV diastolic dysfunction reduces the filling of LA content to the LV during diastole; (2) LA diameter changes during diastole as a new and practical method for the differentiation of the normal-pseudonormal mitral flow pattern.

Adult↗
PubMed2000

Interventricular septal hydatid cyst.

In this report we describe an unusual case of cardiac echinococcus located in the interventricular septum invaded by a cystic mass. It was demonstrated by using transthoracic echocardiography (TTE) and confirmed with magnetic resonance imaging (MRI). Surgical excision (cystopericystectomy) was performed on the patient as a curative therapy. Early recurrence was observed despite additional medical therapy with albendazole.

Adult↗
PubMed1999

Microbubbles associated with mechanical heart valves: their relationwith serum lactic dehydrogenase levels.

BACKGROUND: There has been no consensus about the prevalence and mechanism of generation of microbubbles in mechanical prosthetic heart valves (PHV). The aim of this study was to determine the prevalence of microbubbles in PHV and their relation to serum lactic dehydrogenase (LDH) levels. METHODS AND RESULTS: We prospectively studied 150 normally functioning mitral PHV (98 bileaflet and 52 monoleaflet) in 150 patients with the use of transesophageal echocardiography with a multiplane 5-MHz probe. None of the patients had an aortic prosthetic valve. Blood was drawn to determine serum LDH level. None of the patients had any factors that might affect the LDH level other than the PHV-related hemolysis. Patients with spontaneous echo contrast in the left atrium that might affect the assessment of the microbubbles were excluded. We devised a method to determine the amount of microbubbles for each PHV. Microbubbles were detected in 118 (79%) of 150 PHV, including 97 (99%) of 98 bileaflet valves and 21 (40%) of 52 monoleaflet (tilting disk) valves (P <. 0001). Intraobserver variability was not statistically significant for the determination of the amount of microbubbles (z = 1.7, P =. 08). There was a strong correlation between serum LDH levels and the amount of microbubbles (rs = 0.69, P <.001). CONCLUSIONS: Microbubbles were detected in more patients than reported previously. They were found to be associated more with the bileaflet than the monoleaflet PHV. Sorin monoleaflet valves were associated with microbubbles significantly less often than the others. There was a strong correlation between serum LDH levels and microbubble counts, which suggests that hemolysis may be related to microbubble formation.

Adult↗
PubMed1998

Validation of flow convergence region method in assessing mitral valve area in the course of transthoracic and transesophageal echocardiographic studies.

The purpose of this study was to determine the diagnostic value of flow convergence region method (FCR) to complement well-accepted techniques in assessing mitral valve area (MVA). Fifty-three patients (39 women, 14 men) were enrolled in the study. Transesophageal echocardiography (TEE) was performed after transthoracic echocardiographic (TTE) evaluation, and all measurements were performed for each patient. Mean MVA values determined by different methods both in TEE and TTE studies did not differ (p = not significant). In 51 (96%) patients, TEE and TTE were feasible and measurements of MVA with FCR correlated well with the conventional methods (r = 0.87, standard error of the estimate = 0.13 cm2). In TEE, MVA determined by FCR also correlated well with that obtained by the "pressure half time" method (r = 0.90, standard error of the estimate = 0.11 cm2). Results of our study confirmed the feasibility and accuracy of FCR. Because TEE provides reliable estimation of MVA by FCR, intraoperative monitoring by TEE should be considered as a comparative alternative method.

Adult↗
PubMed1998

Prevalence of microbubbles associated with mechanical prosthetic cardiac valves: a prospective transesophageal echocardiography study.

BACKGROUND AND AIM OF THE STUDY: The study aim was to identify the prevalence of microbubbles in different types of mechanical cardiac valve and, if feasible, to associate microbubbles with various clinical conditions, including thrombotic occlusion of the valves. METHODS: A total of 153 mechanical prosthetic valves were studied (58 aortic, 95 mitral) in 140 patients, prospectively. All valves were functioning normally. In addition, eight mitral prosthetic valves were selected without microbubbles and with an obstructive valvular thrombosis that had undergone successful thrombolysis (group 1); a further eight patients with unsuccessful thrombolysis (group 2) were studied by transesophageal echocardiography before and after thrombolytic therapy. RESULTS: Microbubbles were detected in 75% (114/153) of prosthetic valves, 99% (88/89) of bileaflet valves, and 45% (29/64) of monoleaflet valves (p < 0.0001). Only 14% (4/28) of Sorin monoleaflet valves were associated with microbubbles, which is distinctively less than other valves (p < 0.001 for each); 71% and 77% of aortic and mitral prosthetic valves, respectively, were associated with microbubbles (p = NS). Prosthetic valves with an obstructive thrombosis and no microbubbles in group 1 showed new appearance of microbubbles in 88% (7/8) of cases after successful thrombolysis. Absence of microbubbles in group 2 persisted in all eight patients at the second examination. CONCLUSIONS: Microbubbles were detected in a greater proportion of patients than reported previously and were found to be associated more with bileaflet prosthetic heart valves than with monoleaflet valves. Sorin monoleaflet valves were associated with microbubbles dramatically less than all other valves. The new appearance of microbubbles after thrombolytic therapy of mechanical prosthetic heart valves with an obstructive thrombosis may indicate successful thrombolysis.

Adult↗
PubMedDate not supplied

Congenital sinus of valsalva aneurysm dissecting into the interventricular septum with left ventricular communication.

In this report we describe a case of a right coronary sinus of Valsalva aneurysm dissecting into the interventricular septum with spontaneous rupture into the left ventricle. Sufficient information was provided by echocardiography, cardiac catheterization, and aortography to confirm the diagnosis. Surgical findings were in complete accordance with cross-sectional and color flow Doppler imaging by transthoracic and transesophageal approaches.

Adult↗
PubMedDate not supplied

Assessment of QT interval duration and dispersion in athlete's heart.

An athlete's heart is characterized by morphological and functional changes occurring as a consequence of regular physical exercise. We sought to determine if these physiological changes lead to ventricular repolarization abnormalities in trained athletes. Forty-four trained athletes and 35 sex- and age-matched healthy sedentary controls were included in the study. A 12-lead surface electrocardiogram (ECG) was obtained from all participants. Maximum QT (QTmax) and minimum QT (QTmin) interval durations, QT dispersion (QTd) and corrected QT dispersion (QTcd) were calculated for each ECG record. Heart rate, systolic and diastolic blood pressure values were found to be identical in both groups. QTmax and QTmin interval durations were not statistically different between the athletic and control groups. Similarly, QTd and QTcd did not differ significantly between the two groups. No association was observed between an athlete's heart and ventricular heterogeneity compared with healthy sedentary controls, despite physiological and structural changes.

Adult↗