PubMed Health⌕ Search

Biomedical subjects

Y Beyth

Publications and source records attributed to Y Beyth.

At least 181 records · Page 10Linked to original sources

Foreign body granulomas in peritubal and periovarian adhesions: a possible cause for unsuccessful reconstructive surgery in infertility.

A major problem in tubal reconstructive surgery is the recurrence of peritubal and periovarian adhesions which negate the surgical endeavors. In many cases the etiology of these adhesions is obscure. Histologic re-evaluation with polarized light of 49 resected adhesions revealed residual cornstarch glove powder and suture material in seven specimens. It is concluded that cornstarch powder may be an active agent, and may not be as innocuous as its widespread use indicates.

Fallopian Tubes↗

Inhibitory effect of alpha-fetoprotein on the binding of myasthenia gravis antibody to acetylcholine receptor.

The binding of myasthenia gravis antibody acetylcholine receptor (AcChoR) as measured in vitro by Radioimmunoassay with 125I-labeled alpha-bungarotoxin (alpha-BuTx), can be blocked by amniotic fluid, maternal serum, and umbilical cord serum. This inhibitory effect is due to alpha-fetoprotein present in high concentrations in amniotic fluid and serum, as shown by: (i) selective removal of several components from amniotic fluid and serum; (ii) selective addition of different components present in amniotic fluid and serum, including alpha-fetoprotein, to be radioimmunoassay; (iii) correlation between the inhibitory effect of both amniotic fluid and serum and between the amounts of alpha-fetoprotein they contain; (iv) blocking of the alpha-fetoprotein in vitro suggests a similar effect in vivo in pregnant women with myasthenia gravis. This effect may explain in part the variability in the development of neonatal myasthenia gravis in the babies, due to transplacental transfer of maternal anti-AcChoR antibody, only after delivery and only in the minority of the cases. It also may explain the appearnace of remissions in females with myasthenia gravis during the second and third trimesters of pregnancy. Similar phenomena observed during pregnancy in other autoimmune and immunopathogenic diseases also might be attributed to activity of alpha-fetoprotein.

Acetylcholine↗

A simple technique for visualization of the vagina during ultrasound scanning.

A simple method for clear visualization of the vagina during ultrasound scanning is described. A sealed cylinder, filled with water, is introduced into the vagina. This device, used when the urinary bladder is full, improves visualization of the pelvic organs and facilitates interpretation of the scans. The technique may be employed during all stages of pregnancy, provided there is no bleeding or dilatation of the cervix.

Female↗

Ovarian implantation into the uterus (Estes operation): clinical and experimental evaluation.

Ovairan implantation into the uterus was performed in 27 women, none of whom conceived during the 4- to 6-year follow-up period. Bypassing the fallopian tube may, in itself, explain the disappointing results of this procedure in our series as well as in those reported in the literature. Experimental ovarian implantation into the uterus of rats supplied information regarding additional factors underlying the low success rate of this operation. It is concluded that this surgical intervention has been made superfluous in view of the poor results and the modern methods for extracorporal fertilization at present being developed.

Animals↗

The role of fetal movements assessment in cases of severe RH immunized patients.

Two cases of severe Rh-immunization are presented. The obstetric history, maternal serum anti-D titre, amniotic fluid spectrophotometric evaluation, amniography and ultrasound placentography suggest the diagnosis of hydrops fetalis. The reduction of fetal movements until cessation in the presence of an audible fetal heart point to a severely distressed fetus and impending death, thus providing additional data confirming the diagnosis of hydrops fetalis. The importance of diagnosed hydrops fetalis lies in the fact that most authors agree that in these cases treatment of the fetus should not be attempted.

Adult↗

Autologous blood transfusions and pregnancy.

The application of autologous and frozen red blood cell (RBC) programs is described for 3 pregnant women with antibodies to high-incidence blood group antigens (anti-Lutheranb, anti-Cellano, anti-Vel). The cases illustrate how readily available supplies or rare blood types can be maintained throughout pregnancy using autologous and frozen RBC techniques, including selective predeposit, "family-sharing," and intensive phlebotomy with fluid replacement. The RBC phenotypes described in this paper are exceedingly rare since they occur in only 0.1-0.001% of random donors. However, the principles of autologous blood transfusions are universal and they can be applied to the general problems of blood group incompatibility in pregnancy.

Adult↗

Small marker chromosome mosaicism confirmed in two cases ascertained prenatally.

Two cases of chromosomal mosaicism were prenatally diagnosed and confirmed in tissues cultured from subsequently aborted fetuses. In both cases a small marker chromosome was observed which proved de novo in origin, since parental chromosomes were normal. The implications and interpretation of such findings in counselling families undergoing amniocenteses is discussed. Mosaicism for small marker chromosomes may be more frequent than hitherto suggested.

Adult↗

Potentially deleterious effect of cornstarch glove powder in tubal reconstructive surgery.

Even with the most painstaking techniques, cornstarch granules used as surgical glove powder are deposited in the abdominal cavity during laparotomy. In tubal reconstructive surgery, aimed at the elimination of fibrous adhesions, this deposition may have undesirable consequences. After a successful operation, starch particles introduced in the abdominal cavity may result in the formation of new adhesions. It is therefore desirable to develop an alternative, completely nonreactive, glove powder.

Fallopian Tubes↗

Prenatal diagnosis of mucolipidosis IV by electron microscopy.

Mucolipidosis IV, a recently recognized metabolic storage disease, is characterized clinically by corneal opacity in infancy, full facial features, and psychomotor retardation. Electron microscopy of cells from a 2-year-old affected girl revealed multiple cytoplasmic storage bodies. Cultured amniotic fluid cells, in two subsequent pregnancies, demonstrated similar abnormal storage bodies. Electron microscopic examination of various uncultured tissues from one abortus demonstrated abnormal inclusions in the cells of the brain, cornea, conjunctiva, and other epithelial tissues, thus confirming the prenatal diagnosis. This suggests that mucolipidosis IV is an autosomal recessive trait and demonstrates the efficacy of electron microscopy in the prenatal diagnosis of metabolic storage diseases whose biochemical defect is yet unknown.

Amniotic Fluid↗

Prenatal diagnosis and gonadal findings in X/XXX mosaicism.

Prenatal diagnosis of a case of X/XXX mosaicism is presented. In spite of the fact that over 50% of the cells cultured from both ovaries were trisomic for the X chromosome, fetal öocytes were rarely found. This case illustrates that the presence of a triple-X cell line, even in a relatively high percentage of ovarian cells, does not necessarily protect the ovary from 'aöogenesis'. This observation might prove useful in the counselling of future cases involving the prenatal detection of sex chromosome mosaicism.

Adult↗

Amniogenic bands associated with facial dysplasia and paresis.

A case of the amniogenic band syndrome is described with typical digital constriction bands amputations and syndactyly. The amniotic bands were demonstrated macroscopically and histologically, thus establishing the diagnosis. Facial dysplasia and unilateral facial paresis were attributed to undefined mechanical effects following amniotic rupture. In addition, there was evidence of partial umbilical cord compression which did not appear to have affected fetal well-being.

Abnormalities, Multiple↗