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Biomedical subjects

Y Camille

Publications and source records attributed to Y Camille.

6 recordsLinked to original sources

Carbamazepine and hyponatremia in patients with affective disorder.

The authors assessed 20 carbamazepine-treated patients for the development of hyponatremia. None of the patients had readings below 135 meg/liter of sodium before carbamazepine therapy, but five (25%) did have such readings after carbamazepine therapy. Three of these patients developed frank symptoms of hyponatremia within 1-3 months of the start of therapy. In one patient, hyponatremia developed after rechallenge with carbamazepine. The authors suggest that caution be used in prescribing carbamazepine to patients with low or borderline low sodium values.

Adult↗

Lithium-induced thyroid disorders: a prevalence study.

A group of 116 lithium-treated patients (53 men, 63 women) with predominant diagnoses of affective disorders were systematically examined for the presence of thyroid disorders. Nine (7.8%) patients (2 men, 7 women) were found to suffer from hypothyroidism after a mean of 3.4 years of lithium therapy. An increase in thyroid-stimulating hormone without clinical hypothyroidism was noted in 2 (1.7%) patients (both men). Hyperthyroidism with a full-blown picture of thyrotoxic nodular goiter was noted in 1 woman, and temporary increases in thyroxine and triiodothyronine were noted in another woman. These findings are discussed in light of other studies.

Aged↗

Carbamazepine, diuretics, and hyponatremia: a possible interaction.

Although carbamazepine is known to cause hyponatremia, no previous reports have indicated an interaction between carbamazepine and a diuretic. Two patients are described who were treated with this combination and developed symptomatic hyponatremia, which cleared when both drugs were discontinued in one patient and when the diuretic was discontinued in the second patient. The possible mechanisms of action of carbamazepine-induced hyponatremia are discussed.

Aged↗

Tardive dyskinesia in the course of antidepressant therapy: a prevalence study and review of the literature.

The authors present a prevalence study of tardive dyskinesia (TD) in the course of antidepressant therapy. Of the 50 patients evaluated, three developed TD. TD developed rapidly and in a short period of time. Withdrawal of antidepressant improved TD in two patients. The literature on TD developing in the course of antidepressant therapy is reviewed, and the different etiological theories are examined.

Adult↗

Prevalence of bipolar disorder in a psychogeriatric population.

Bipolar affective disorder arising for the first time in old age (60 years and over) has not been extensively studied. The authors present a prevalence study of mania arising after age 60. Of 217 patients admitted to our unit in a 2-year period, 10 (4.7%) showed symptoms of mania, using the DSM-III criteria. This constitutes 9.3% of 108 affective disorder patients admitted during the same period. An important factor in the precipitation of these attacks was marital discord, leading, in several cases, to separation, even in this age group.

Aged↗

The prevalence of late-onset schizophrenia in a psychogeriatric population.

Of 288 patients admitted to our psychogeriatric unit during a 4-year study, seven patients were diagnosed as having symptoms of paranoid schizophrenia (2.4% of all admissions). All the patients were women. Their symptoms included bizarre delusions and auditory hallucinations. Negative symptoms were rare. Attempts to reduce the dosage of neuroleptic medication led to reappearance of the symptoms in six patients and readmission of the seventh.

Aged↗