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Biomedical subjects

Y Diraison

Publications and source records attributed to Y Diraison.

At least 19 recordsLinked to original sources
PubMed2001

[BIS monitoring may allow the detection of severe cerebral ischemia].

PURPOSE: To show that the bispectral index (BIS) is not only a monitor of the depth of anesthesia but that acute decreases of the index may be related to severe cerebral ischemia. CLINICAL FEATURES: Several clinical observations suggest that an unexplained fall of the BIS may be the result of cerebral ischemia. Somatosensory evoked potentials decreased in parallel to the decrease in BIS during carotid clamping in a 58-yr-old patient undergoing carotid endarterectomy. In a 62-yr-old patient undergoing resection of an aortic aneurysm, the BIS decreased from 40-50% to 8% as the cardiac index and central venous O(2) saturation decreased. The BIS returned to normal values when the low cardiac output was corrected pharmacologically. CONCLUSION: While the BIS is a well accepted monitor of the depth of anesthesia, several factors, unrelated to anesthesia, can modify the index. Thus, to adjust the level of anesthesia based solely on the BIS could be inappropriate. While the sensitivity and specificity of the BIS for this indication have not been determined, we suggest that the BIS may be useful to detect severe cerebral ischemia.

Brain Ischemia↗
PubMed1993

[Continuous infusion of vancomycin in post-neurosurgical staphylococcal meningitis in adults].

Eight adult patients with post-surgery meningitis caused by methicillin-resistant staphylococci were treated with continuous intravenous infusion of vancomycin in mean doses of 50 mg/kg/day. This treatment, which lasted 3 to 6 weeks, was well tolerated by the kidneys and resulted in cure in all cases; its effect on the ear was not evaluated. Stable concentrations of 4 to 7 mg/l in cerebrospinal fluid were obtained after the 48th hour of treatment.

Adult↗
PubMed1992

[The value and limitations of autotransfusion in traumatology].

29 autotransfusions were realised in severe cases of trauma (20% of a sample of 143 traumatic emergencies). The recovery of haemothorax blood as well as the peroperative collection by a Cell Saver allowed the retransfusion of 1989 +/- 1,838 ml (225-7070 ml) of autologous blood, amounting to 56% of the average blood loss. A total of 69% of the patients received homologous blood. Eight patients (where the haemorrhage amounted to 143% of the blood volume) showed some coagulation troubles. Autotransfusion assures the immediate availability of blood while reducing the immunological and viral transfusion risks. Therefore haemothorax autotransfusion should be used systematically. Peroperative recollection by a cell-separator works well but is technically more tedious.

Adult↗