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Biomedical subjects

Y Elad

Publications and source records attributed to Y Elad.

6 recordsLinked to original sources

Mycorrhiza-induced changes in disease severity and PR protein expression in tobacco leaves

The development of leaf disease symptoms and the accumulation of pathogenesis-related (PR) proteins were monitored in leaves of tobacco (Nicotiana tabacum cv. Xanthinc) plants colonized by the arbuscular mycorrhizal fungus Glomus intraradices. Leaves of mycorrhizal plants infected with the leaf pathogens Botrytis cinerea or tobacco mosaic virus showed a higher incidence and severity of necrotic lesions than those of nonmycorrhizal controls. Similar plant responses were obtained at both low (0.1 mM) and high (1.0 mM) nutritional P levels and with mutant plants (NahG) that are unable to accumulate salicylic acid. Application of PR-protein activators induced PR-1 and PR-3 expression in leaves of both nonmycorrhizal and mycorrhizal plants; however, accumulation and mRNA steady-site levels of these proteins were lower, and their appearance delayed, in leaves of the mycorrhizal plants. Application of 0.3 mM phosphate to the plants did not mimic the delay in PR expression observed in the mycorrhizal tobacco. Together, these data strongly support the existence of regulatory processes, initiated in the roots of mycorrhizal plants, that modify disease-symptom development and gene expression in their leaves.

Journal Article↗

Effects of inhaled humidified warm air on nasal patency and nasal symptoms in allergic rhinitis.

The effects of inhaled warm air on nasal patency and on allergic rhinitic symptoms were studied in 102 patients. Treatment consisted of two consecutive 30-minute sessions, during which the patient inhaled saturated, hot (42-44 degrees C) air through the nose. The treatment was repeated 1 week later. During the week following each treatment, every patient recorded his or her subjective response on a daily symptom score card. Nasal patency was determined before and after each treatment by measuring peak nasal inspiratory and expiratory air flow and by measuring the area covered with vapor formed by the exhaled air on a plate. Highly reproducible results were obtained by using these three objective methods. Inhalation of humidified warm air resulted in amelioration of allergic rhinitis symptoms and in increased nasal patency in a high proportion of patients. There were no adverse side effects. This form of therapy seemed effective in the 2-week period in which it was used and would be an additional form of therapy available for those suffering discomfort from allergic rhinitis.

Adolescent↗

Possible role of lectins in mycoparasitism.

Lectin activity in a host-mycoparasite relationship was demonstrated with Rhizoctonia solani and Trichoderma harzianum. Attachment of O but not A and B erythrocytes to hyphae occurred on R. solani but not on its mycoparasite. This phenomenon, which was Ca2+ and Mn2+ dependent, was prevented by galactose, present in T. harzianum cell walls, and by fucose.

ABO Blood-Group System↗

Effects of steam inhalation on nasal patency and nasal symptoms in patients with the common cold.

The effects of steam inhalation on nasal patency and on nasal symptoms were studied in 62 patients with the common cold by a double-blind, randomized, placebo-controlled clinical trial. Treatment consisted of two 20-minute sessions, during which the patient inhaled saturated, hot (42 degrees to 44 degrees C) air through the nose. The subjective response was recorded by each patient during the week following treatment on a daily symptom score card. Nasal patency was determined before treatment, the following day, and 1 week later by measuring peak nasal expiratory and inspiratory air flow. Highly reproducible results were obtained by using these objective methods. Steam inhalation resulted in alleviation of cold symptoms and increased nasal patency in a significantly higher percentage of patients in the actively treated group than in the placebo-treated group. Possible explanations for the effectiveness of treatment are discussed.

Adolescent↗

Effects of elevated intranasal temperature on subjective and objective findings in perennial rhinitis.

The effects of elevated intranasal temperature on symptoms and signs of perennial rhinitis were studied in 78 patients by a double-blind, randomized, placebo-controlled clinical trial. Patients were subjected to two treatments separated by a 1-week interval. Each treatment consisted of three 30-minute sessions, during which the patient's intranasal temperature was raised by inhalation of saturated hot air (42 degrees C to 44 degrees C). Subjective response was recorded on a daily symptom score card during the week following treatment. Nasal patency was determined before and after treatment by measuring maximal nasal expiratory and inspiratory airflow and by measuring the area covered with vapor formed by the exhaled air on a plate. Highly reproducible results were obtained by using these three objective methods. Elevation of intranasal temperature resulted in amelioration of rhinitis symptoms and in objective evidence of increased nasal patency in a significant percentage of patients compared to the placebo-treated group.

Adult↗