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Biomedical subjects

Y Erk

Publications and source records attributed to Y Erk.

At least 19 recordsLinked to original sources
PubMed1999

Bartsocas-Papas syndrome with fusion of the lips and posterior fusion defects of the thoracic vertebrae.

Bartsocas-Papas syndrome is a rare popliteal pterygial syndrome with multiple anomalies including microcephaly, facial clefts, filiform bands, ankyloblepharon, syndactyly, and other ectodermal anomalies. Affected infants usually die perinatally. The authors present an 8-month-old female infant with manifestations of this syndrome and some additional traits including fusion of the lips, intraoral filiform bands, alopecia totalis, and posterior fusion failure of the vertebrae. The fused lips were opened by incising the fibrotic bands closing her mouth. Details of this patient and a brief review of the literature is presented.

Abnormalities, Multiple↗
PubMed1999

Phlebolithosis.

Explore the source record for details and available documents.

Adolescent↗
PubMed1997

Malignant melanoma in xeroderma pigmentosum patients: report of five cases.

Xeroderma pigmentosum is a rare genetic disease transmitted via a recessive gene with an altered reaction of the epidermis to light. Fifty per cent of patients develop a skin tumour by 8 years of age. The majority of patients may have multiple tumours, but metastasis is rare. In the last 25 years we have treated 24 xeroderma pigmentosum patients in our clinic. Only five patients had developed cutaneous malignant melanoma during their follow-up. Three of the patients were from the same family, melanoma occurring in three of five affected individuals. All xeroderma pigmentosum patients with malignant melanoma had received classical treatment modalities. Except one case of fulminant pattern, all four patients had long disease-free survival. Although early detection and treatment of these cutaneous malignancies will reduce morbidity and mortality, genetic counselling remains the most important protective measure for xeroderma pigmentosum.

Adult↗
PubMed1995

Repeated mandibular lengthening in Treacher Collins syndrome: a case report.

A patient with mandibular hypoplasia associated with Treacher Collins syndrome was treated by bilateral distraction osteogenesis. Since less than optimal length was provided by the first distraction, a second corticotomy was performed in the newly formed bone 6 months after the first distraction. Thus bone gained by distraction osteogenesis was subjected to distraction once again. New bone formation occurred after the second lengthening. This case illustrated that distraction osteogenesis may be applied to the mandible at the site of previous distraction.

Bone Lengthening↗
PubMed1994

Modified split-level lid resection for blepharoptosis.

Mustardé's split-level lid resection surgery was popular through the 1980s for the correction of blepharoptosis with 7 mm or more of levator function. Although the aesthetic results gained with this technique were good, last line deformity and eyelid margin irregularities, such as central peaking at forward and upward gaze, were experienced. A simple modification of the tarsal resection pattern of Mustardés operation has solved these complications. In the treatment of 24 ptotic eyelids (12 unilateral, 6 bilateral with a modified split-level lid resection procedure), symmetrical appearance and level eyelids were obtained without lid margin peaking at 5 years' follow-up. The only persistent complication was lid lag at down-gaze in 10 eyelids.

Adolescent↗
PubMed1993

Use of a subfascial pocket on the contralateral calf for salvage of an avulsed foot.

Cross-leg fasciocutaneous flaps have long been used for reconstruction of defects on the contralateral foot. This report describes the use of a cross-leg subfascial pocket for preservation of avulsed metacarpal and phalangeal bones and reconstruction of both plantar and dorsal aspects of the contralateral foot. The avulsed metacarpal bones and phalanges of the foot were embedded into a subfascial pocket prepared on the contralateral calf in the first operation. The gastrocnemius fasciocutaneous flap was then used for reconstruction of the contralateral foot. The avulsed structures were kept vital during the 20 days that elapsed between these two procedures.

Foot↗
PubMed1993

Unilateral absence of the soft palate: case report of reconstruction with a mucoperiosteal island flap.

Congenital absence of half of the soft palate is a rare deformity. There is little in the literature about its definition and management. This article presents a case with velopharyngeal insufficiency caused by unilateral absence of the soft palate. The patient was treated with a modification of the mucoperiosteal island flap, first designed by Millard, to provide nasal lining during pushback lengthening of a short cleft palate. The speech quality of the patient improved noticeably after the operation. Although island flap has limited use in primary cleft palate surgery, it may be effective in reconstruction of soft palate defects, when standard pushback procedures are not adequate for solving the problem.

Child↗
PubMed1992

Reconstruction of postburn breast deformities.

Postburn breast deformity is a sequela of severe scar contraction of the burned chest. During the past 3 years, 24 female patients with such deformities required reconstruction, the surgery was performed in our department. These patients, the types of the deformities and the techniques used for reconstruction have been reviewed. For mild deformities (10 patients) reconstructions with skin grafts and local skin flaps were found to be satisfactory. For deformities which affected the mammary development (14 patients), mammary prostheses directly or under the soft tissue obtained by skin expansion or musculocutaneous flaps were used. In three of our patients, reduction mammaplasty or mastopexy was needed to symmetrize the breasts.

Adolescent↗
PubMed1983

Critical comparison of transcutaneous PO2 and tissue pH as indices of perfusion.

A critical laboratory evaluation of transcutaneous PO2 monitoring and tissue pH monitoring in lower abdominal island flaps based on the superficial inferior epigastric vessels in rabbits revealed that transcutaneous PO2 values correlate poorly with tissue survival under circumstances of decreased arterial inflow. The inability of the transcutaneous PO2 monitor to accurately predict viability of the flaps in this study is attributed to physiologic changes in the microcirculation and not to instrument error. Tissue pH was, in all instances, a reliable index of the perfusion status of the flaps.

Abdomen↗
PubMed1983

Vascular augmentation of skin and musculocutaneous flaps.

In a series of rats, pigs, and dogs, a method for ligating an expendable vessel and placing it under a skin flap or using the vessel to create a new pedicle (neovascular pedicle) for a musculocutaneous flap by the process of neovascularization is demonstrated. No ischemic stimulus is necessary to induce this process of transmural neovascularization.

Animals↗
PubMed1983

Tissue pH monitoring in microsurgery: a preliminary evaluation of continuous tissue pH monitoring as an indicator of perfusion disturbances in microvascular free flaps.

In an experiment using a continuous tissue pH monitoring system, selective occlusion of the vessels supplying lower abdominal island flaps in Sprague-Dawley rats resulted in predictable tissue pH changes. Arterial occlusion resulted in a rapid fall in pH. In all three experimental groups, the steepest rate of pH drop occurred during the first 30 minutes postocclusion. In a series of 9 patients who underwent microvascular free flap surgery the continuous pH monitor was employed postoperatively. Tissue pH was (and remained) normal in well-perfused free flaps. Tissue pH fell almost immediately with anastomotic failures. These findings demonstrate that pH measurement offers the microvascular surgeon a new, simple, and reliable approach to perfusion assessment in free flaps. Perhaps improved survival rates will result from earlier anastomotic exploration in compromised free flaps that exhibit falling pH values.

Adult↗
PubMed1983

A modified gluteus maximus musculocutaneous free flap based on the inferior gluteal vessels.

A single case is reported of a large posterior calf defect, involving skin, subcutaneous tissue, and underlying muscle, in which contour is restored employing an inferior half of the gluteus maximus musculature and overlying skin as a free flap. In this patient a bulk of tissue was moved using microvascular surgical techniques while maintaining minimal donor site deformity.

Buttocks↗
PubMed1983

Electric current arterial injury: a laboratory model.

A laboratory model capable of creating reproducible, nonlethal, fourth-degree type electrical extremity burns in rats was developed. Fifty-seven rats were studied immediately after burn to 90 days after burn with microdissections, light microscopy, microangiography, and flow studies. Progressive necrosis was not observed. Minimal major vessel arterial injury was demonstrated. This significant finding supports the concept of early debridement and reconstruction to include possible free tissue transfer.

Animals↗
PubMed1983

Dimethyl sulfoxide alteration of collagen.

In vitro incubation of human scar in our laboratory with 99% DMSO demonstrated, by electron microscopy, the disruption of the collagen fibers. This may prove to be a useful preparatory step for selective enzymatic assault upon exuberant or undesirable scar tissue in the clinical setting. Further study of this concept is planned.

Collagen↗
PubMed1982

Direct microvascular monitoring with implantable ultrasonic Doppler probes.

A method for constructing high-frequency pulsed Doppler ultrasonic microprobes is described. Such probes were constructed and implanted on the femoral arteries of 14 rats. All of the probes gave excellent signals during the early postoperative period and all probes were found to be functional when retrieved one month after implantation. We feel that high-frequency pulsed Doppler microprobes have important advantages for microvascular monitoring.

Animals↗