PubMed Health⌕ Search

Biomedical subjects

Y F Fong

Publications and source records attributed to Y F Fong.

25 records · Page 2Linked to original sources
PubMed1998

The role of prophylactic iron supplementation in pregnancy.

The prevalence, causes and role of iron prophylaxis in pregnant women was studied. All women delivered at the National University Hospital, Singapore in 1993 had their haemoglobin estimated. If it was less than 11 g/dl, blood was taken for serum iron, ferritin, transferrin, red cell zinc protoporphyrin, serum folate, vitamin B12 and thalassemia screen to establish cause of anaemia. Data was also collected with regards to their antenatal progress and iron prophylaxis. Logistic regression, Chi-square test, Fischer's exact test and Mantel-Haenszel tests were also used to assess the relationships between categorical variables. The prevalence of anaemia at first antenatal visit was 20.6% while the prevalence of anaemia at delivery was 15.3%. The commonest cause of the anaemia in pregnancy was due to iron deficiency (81.3%). In the non-anaemic group, 90.7% were on prophylactic iron supplements compared to 50.6% in the anaemic group (P < 0.001). Of the 752 women found to be anaemic at booking, 591 received prophylactic iron supplements while 161 women did not. A total of 166 (28.1%) of those with iron supplements were anaemic at delivery, whereas 140 (87.0%) of those who did not receive prophylactic iron remained anaemic at delivery (P < 0.001). Of the 2516 non-anaemic women who received prophylactic iron, 118 (4.7%) developed anaemia at delivery while 133 (34.1%) out of the 390 women who did not receive prophylactic iron were anaemic at delivery (P < 0.001). Multivariate logistic regression analysis revealed the odds of anaemia for a woman not on iron therapy was about 11 times that of her counterpart on prophylactic iron therapy (95% CI 8.76 to 14.13). A 55% reduction in odds of anaemia was estimated per 1 gm% increase in haemoglobin at booking. Prophylactic antenatal iron supplements not only prevent a fall but also improved haemoglobin levels during pregnancy. Those who were not on any iron supplements were 11 times more likely to develop anaemia in the present pregnancy.

Anemia↗
PubMed1997

Rubella seroprevalence in the Singapore Armed Forces (SAF) and the changing need of the SAF rubella immunisation programme.

A seroepidemiological study on the prevalence of rubella antibodies in a cohort of Singapore Armed Forces (SAF) recruits was conducted in 1994, twelve years after rubella immunisation was routinely given to primary 6 school boys in 1982. The results showed a high level of immunity (97.1% seropositive) in the study cohort. The implication of this finding is that it may no longer be necessary to routinely immunise recruits on entry into the SAF against rubella; the latter can be limited to those with no evidence of prior rubella immunisation.

Adult↗
PubMed1992

Acceptability of Norplant implants for fertility regulation in Singapore.

The continuation rate at the end of this five-year clinical study was 60% with no accidental pregnancy occurring throughout the five years. The post-removal conception rate in women desiring pregnancy was 92% at the end of two years. The majority of acceptors described the overall experience with the implants as favourable. In fact, 75% of the women planning to use contraception after removal of the implants were going to use implants again.

Adult↗
PubMed1992

Attitudes to AIDS and sexual behaviour among a cohort of medical students in Singapore.

A survey conducted in 1990 among final year medical students found that most respondents had a good knowledge about AIDS and its routes of transmission. Among the 13.7% of respondents that were sexually active, it was noted that only 35% had used the condom before and that only 20% had used it in the most recent occasion of sexual intercourse. It was noted that only 30% of the sexually active had intention using the condom when they next have sexual intercourse despite the fact that 40% of them were having sexual intercourse with causal partners. Despite having a high knowledge of AIDS, medical students at the National University of Singapore have a low use of condoms.

Acquired Immunodeficiency Syndrome↗
PubMed1991

A reversal of fertility trends in Singapore.

Free access to contraception and effective legislation measures, have resulted in a decline in fertility in Singapore. A new population policy of 'three children or more if you can afford it' was therefore introduced in 1986. This paper discusses the new population policies and measures their effect on fertility in Singapore.

Birth Rate↗
PubMedDate not supplied

Preparation of the cervix for surgical termination of pregnancy in the first trimester.

Worldwide, surgical vacuum aspiration is the method of choice of terminating first trimester unwanted pregnancy. Cervical priming prior to surgical evacuation reduces the risks of cervical injury by making the cervix softer and easier to dilate. Over the years, a number of effective methods of cervical priming have became available: osmotic dilators; antiprogesterone and prostaglandins. Of these, prostaglandins remain the most widely used method of cervical preparation. However many of the natural and synthetic analogues of prostaglandins are either expensive or associated with troublesome side-effects. More recently, misoprostol, a synthetic 15-deoxy-16 hydroxy 16-methyl analogue of naturally occurring prostaglandin E, used in the management of peptic ulcers, has established a lead for cervical priming in terms of availability, ease of administration, cost and effectiveness. In fact it appears that both oral and vaginal misoprostol given at dosages of 400 microg are effective for cervical priming when administered 3 h prior to surgical vacuum aspiration. Now that the use of misoprostol for cervical priming has been validated, its widespread use in gynaecological practice is expected.

Abortifacient Agents, Nonsteroidal↗