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Biomedical subjects

Y Fonck-Cussac

Publications and source records attributed to Y Fonck-Cussac.

At least 19 recordsLinked to original sources
PubMed1983

[Bronchiolar cells of the human fetal lung from 15 to 26 weeks of gestation].

The authors report an ultrastructural study about the human fetal bronchiole from seven human fetus which gestational age extend from fifteen to twenty-six weeks. It follows a precedent report concerning the pulmonary acinus. It is thus possible to definite the happening date of the different cellular populations of the bronchiolar layer, their morphology, their distribution, and their differentiation modalities. All those cells have the same endodermal origin from the undifferentiated columnar cell. From the fifteenth week, the three main cellular patterns with a full differentiated aspect are present: ciliated cell, Clara cell, and neurosecretory cell and as a fourth type: the intermediary aspect cell; but the undifferentiated columnar cell is still predominant. From the nineteenth week, those four cellular patterns are predominant. At last, the connection between alveolar and bronchiolar layers is studied at the bronchiolo-alveolar junction. From those data and the literature, the authors consider the bronchiolo-alveolar renewal, in which they think that the Clara cell and/ or an immediate precursor could take a leading part.

Female↗
PubMed1983

[Electron microscopy study of the development of the pulmonary alveolus in the human fetus].

An ultrastructural study of distal human fetal lung between the fifteenth and nineteenth weeks of gestation is performed. All the cells of the epithelial lining layer have an endodermal origin and are provided by one cellular pattern: the columnar undifferentiated cell. From nineteenth week of gestation a differentiation into alveolar et bronchiolar ways is observed. Inside cells which are in type II pneumonocyte differentiation, cytoplasmic modifications has been observed. These modifications can agree with lamellar inclusion bodies precursors. Otherwise, respective part of type II pneumonocytes and Clara cells, in surfactant synthesis is discussed, as well as the chronological link connecting between them the precursors of the lamellar inclusions bodies, and the mode of renewal of alveolar cells.

Cell Differentiation↗
PubMed1981

Eosinophilic fasciitis. Ultrastructural study of an early biopsied case.

A 55-year-old women with eosinophilic fasciitis was biopsied 8 weeks after the onset of her illness. Under the electron microscope the changes were almost exclusively located in the fascia with many active fibroblasts, accumulation of protocollagen fibrils (10-50 A diameter), elastic fibre remodelling and numerous degranulating mast cells. The inflammatory infiltrate was dense and mostly composed of lymphocytes and plasma cells, with 16% eosinophils. The connective tissue changes may be part of a healing process following microinjury of the fascia. However, large numbers of lymphocytes and plasma cells are unusual in the healing process and are more common in the cellular reaction of morphea. Nevertheless, the absence of macrophages in subcutaneous fat, together with large number of eosinophils in the fascia may be considered to be distinctive features of eosinophilic fasciitis.

Biopsy↗
PubMed1979

[The reaction of the insect excretory tissue to a heavy metal: uranyl nitrate (author's transl)].

The present paper describes the modifications induced in Malpighian tubules of Locusta migratoria by uranyl nitrate. These modifications are observed only if doses injected are approximately a hundred times higher than those which affect the renal epithelium of Vertebrates. The elimination of the uranyl salts seem to occur by apical excretion of dense metallo-proteic granules. When strong doses are used, metallic particles are seen on the basal membrane and in the extracellular spaces. Such intracytoplasmic particles are rarely observed.

Animals↗