No-boundary wave function for a simplicial anisotropic universe.
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Biomedical subjects
Publications and source records attributed to Y Furihata.
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A 19 year-old girl with an unusual type of coarctation of the aorta terminating in complete obstruction is presented. At the age of 5 years, she was diagnosed by aortography to have coarctation of the aorta of type IV C according to Edward's classification. No surgical treatment was performed at that time because her growth was good and she didn't have hypertension. During the follow-up period, marked hypertension developed, and she was readmitted. The aortogram revealed a bicuspid aortic valve and total obstruction of the descending thoracic aorta at the site where coarctation was noticed previously. The abdominal aorta distal from the obstruction site was filled through rich collateral circulation. As these angiographic interval changes are very rare, we discussed the genesis of obstruction and operative indication by reviewing the literature.
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An extremely unusual case of myocardial infarction associated with infective endocarditis (IE) is described. A 38-year old male with a high fever was transferred to our hospital for further treatment of IE. Two-dimensional echocardiogram showed a large mycotic aneurysm of the sinus of Valsalva in contact with neighbouring structures. The patient had a rapid recovery within several days after administration of antibiotic agents. However, he then developed abrupt onset of severe precordial pain. From the echocardiogram images and biochemical evaluation he was diagnosed as having an acute subendocardial infarction. Serial echocardiograms revealed expansion of the aneurysm, extending from the myocardium of the anterolateral free wall to the lower margin of the proximal left coronary artery. The cause of acute myocardial infarction was thought to be incomplete occlusion of the coronary artery through compression by the enlarging mycotic aneurysm of the sinus of Valsalva. Urgent surgery confirmed compression of the left coronary artery by the large mycotic aneurysm as the cause of acute myocardial infarction.
A case of Romano-Ward syndrome effectively treated by both propranolol and atrial pacing is reported. A 33 year-old female, who had experienced syncopal episodes since she was 20 years old, had a family history showing her son with QTc 0.46. Her QT-U interval and QTc were both 0.6 second when propranolol was not administered. It shortened to 0.28 second and 0.39 respectively under exercise stress testing, and also shortened to 0.41 second and 0.43 respectively when left satellite ganglion block was used. Electrophysiologic study demonstrated that both sinus and atrioventricular nodal functions were normal, but the refractory periods of right and left ventricle differed significantly, and nonsustained ventricular tachycardia was induced. Her QT-U and QTc intervals shortened to 0.37 seconds and 0.43 respectively through both the treatment of 80 bpm atrial pacing, and the administration of 80mg propranolol. She has never experienced a syncopal episode.
We describe two cases of left atrial myxoma, demonstrating an unusual tumor vascularity as revealed by coronary angiograms. Both cases had suffered typical episodes of transient ischemic attack (TIA). Coronary angiography revealed tumor blood supply from coronary arteries in both cases, and also a leakage of contrast medium from the surface of the tumor blood vessels to the left atrium in one case. In the medical literature available in English reviewed so far, no report of such a leakage has been reported. Selective coronary arteriography can be a useful diagnostic method of delineating left atrial myxoma and its blood supply.
In order to document the localized prevalence of early atherosclerosis in the major coronary arteries, a study using 50 coronary arteriographies was made from Feb. 1984 to Sep. 1985 in Shinshu University Hospital. Early atherosclerotic stenosis had a spatial distribution with strong incidence on the LAD bifurcations which contained the first diagonal branch, RCA which contained RV branches and LCX which contained the OM branch. Upstream of the bifurcations, the stenotic changes were observed to be concentric with the vessel axes. Downstream of the flowdivider, the lesions were gathered proximally and quickly disappeared distally. Lesions tended to occur eccentrically at the lateral walls of the entrance of the smaller branch. The proximal portions of both the RCA and LCA were almost free of disease. We also tried to investigate the relationship between the bifurcation angle branching off the parent vessels and early sclerotic lesions. We found that the angle between the branches and the plane in contact with the surface of the heart is especially important.
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