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Biomedical subjects

Y G Luo

Publications and source records attributed to Y G Luo.

5 recordsLinked to original sources
PubMed2001

[Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura].

OBJECTIVE: To explore the clinical effect of recombinant roasted licorice decoction (RRLD) combined with low-dose glucocorticoids (GC) in treating idiopathic thrombocytopenic purpura (ITP). METHODS: Forty-three patients were divided semi-randomly into the treated group (n = 21) and the control group (n = 22), the former was treated with RRLD plus low-dose GC, and the latter was treated mainly with normal dosage of GC. RESULTS: The total effective rate of the treated group was better than that of the control group, the difference between these two groups was significant (P < 0.05). After treatment the platelet count in the treated group arose from (36.29 +/- 9.70) x 10(9)/L to (95.14 +/- 18.26) x 10(9)/L, while in the control group from (37.31 +/- 9.29) x 10(9)/L to (77.73 +/- 21.96) x 10(9)/L, the RRLD was superior to nat of GC in raising platelet count, the difference between them was also significant (P < 0.01). The treated group was lower obviously than the control group in adverse reaction (P < 0.01). CONCLUSION: The efficacy of RRLD plus low-dose GC is reliable in treating ITP, with less adverse reaction.

Adolescent↗
PubMed1994

[Topography of intraabdominal supra and infra-hepatic IVC and its application in hepatectomy].

Topographic study of infra-diaphragmatic and supra-hepatic IVC (ISIVC) was made in 16 fresh adult cadavers. The diameter and length of ISIVC averaged 35.94 +/- 5.68 mm and 16.87 +/- 5.14 mm respectively, hence making band-blockade of the ISIVC is practical. In clinical application, 21 cases of liver cancer involving the second or third hepatic hilus underwent lobectomy or segmentectomy with temporary band-blocking of the ISIVC, the infrahepatic IVC and the first hepatic hilus to prevent or to treat massive bleeding. In 3 of the 21 cases, the middle hepatic vein was inadvertently torn and was successfully suture repaired with this way.

Adolescent↗
PubMed1993

Safety and immunogenicity of live attenuated hepatitis A virus vaccine (H2 strain) in humans.

A study was made in Neijiang City, Sichuan Province to observe the safety and immunogenicity of a live attenuated hepatitis A virus (HAV) vaccine (H2 strain). 3,031 children, aged 6 to 9 years, were injected subcutaneously with 10(6.0) TCID50, 10(5.5) TCID50, and 10(5.0) TCID50 of HAV vaccine; the seroconversion rate and antibody GMT were 97.52%-90.68%, GMT = 1:5.19 +/- 1.90-1:3.36 +/- 1.94; 84.75%-76.27%, GMT = 1:4.29 +/- 1.96-1:2.0 +/- 2.67; 53.23%-51.61%, GMT = 1:2.57 +/- 1.89-1:1.68 +/- 1.41 respectively after 4 weeks to 12 months of inoculation. Forty-eight children in the control group were anti-HAV negative at 4, 8, and 12 weeks; 21 children in the oral group were not antibody positive 4 and 8 weeks after oral administration of the vaccine. The stool specimens of 3 of the 14 vaccinated children were HAA positive. The results suggest that the live attenuated HAV vaccine (H2 strain) is of good immunogenicity and safety.

Alanine Transaminase↗
PubMed1990

Omental autotransplantation in treatment of thromboangiitis obliterans.

From 1981 to 1985, omental autotransplantation was performed for 28 patients with thromboangiitis obliterans on the left lower extremities in 16 patients, the right ones 11, and the right upper limb 1. The early results in all patients were satisfactory. In 19 patients followed up from 1 to 4 years, the results were encouraging, with the improvement of symptoms after operation. In 18 patients, digital ulcers healed within 2-4 weeks. Doppler and electrical impedance plethysmography examinations showed the blood circulation of affected extremities was markedly improved in the 18 patients except one who had the recurrence of digital ulcer 2 years later. In one of the 19 patients the disease recurred one month after the operation, and a lumbar sympathectomy was performed. The indications, the operative technique, and the mechanism of this operation are discussed.

Adult↗