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Biomedical subjects

Y Gilboa

Publications and source records attributed to Y Gilboa.

At least 19 recordsLinked to original sources
PubMed1991

Transient postpartum diabetes insipidus.

Diabetes insipidus may first present before, during, or immediately after pregnancy. The characteristics of two unusual cases of transient postpartum diabetes insipidus are described and discussed.

Adult↗
PubMed1990

[Treatment of prolactin-secreting pituitary tumors with bromocriptine].

9 women and 6 men with prolactin-secreting pituitary tumors--prolactinomas (mean age 41 years, range 28-57), were treated conservatively with bromocriptine. The women usually presented with galactorrhea, menstrual disorders and headaches, and the men with headaches, decreased libido or impotence, and visual abnormalities. The symptoms had lasted from several months to 20 years, but were not correlated with tumor size. Between 77-100% of symptoms improved during bromocriptine. Prolactin levels, which correlated with the size of the tumor, averaged 1241 ng/ml before treatment and became normal in 80% of the patients. Tumor size decreased in 58% of those with macroprolactinomas. Lesions of decreased density were found in another 17% of the patients. Side-effects of bromocriptine were minor and disappeared despite continuation of therapy. The results of this series, as well as those of others, indicate that bromocriptine is the treatment of choice for micro- and macroprolactinomas.

Adult↗
PubMed1990

Prevalence of thyroid disorders among the elderly in Israel.

The prevalence of thyroid disorders was investigated in 698 elderly people (443 women and 255 men), registered in special family health clinics of the Israel Ministry of Health and in two homes for the aged. The first screening was done by serum thyroxine (total T4) examination, and those with values greater than 150 nmol/l or less than 64 nomol/l underwent further laboratory and clinical evaluation in our endocrinological service. Hypothyroidism was diagnosed in 12 women and 5 men (2.5% of the cohort) and hyperthyroidism in 10 women and 1 man (1.5% of the cohort); thus the prevalence of thyroid disorders among the elderly was 4% in this population.

Aged↗
PubMed1989

Secondary amenorrhea in two sisters with hypogonadotropic hypogonadism and progressive cerebellar ataxia.

The association of familial hypogonadism with progressive cerebellar ataxia is only rarely encountered. Both primary hypergonadotropic and secondary hypogonadotropic hypogonadism may appear with cerebellar ataxia. However, many of these patients suffer from a variety of neurological and/or somatic malformations. Females, which are relatively rarely affected, display primary amenorrhea. In this report, two sisters presented with secondary amenorrhea prior to the appearance of progressive cerebellar ataxia and were found to have hypogonadotropic hypogonadism. This unique family displays clinical evidence for the presence of a possible common mechanism responsible for progressive hypothalamic and cerebellar impairment of late onset.

Adult↗
PubMed1989

Spontaneous pneumopericardium: case report and review of the literature.

An 84-year-old man presented with acute dyspnea and chest pain attributed to his long medical history of cardiorespiratory problems. Admission chest roentgenogram revealed a moderate pneumopericardium and a cavitary lesion in the base of the right lung. The lesion was found to be a bronchogenic carcinoma perforating through the upper pericardium to form a bronchopericardial fistula, confirmed by autopsy. A review of the literature concerning the various causes of pneumopericardium, the clinical features and the principles of treatment is included.

Aged↗
PubMed1988

Prevalence of mitral valve prolapse in chronic lymphocytic thyroiditis and nongoitrous hypothyroidism.

An increased prevalence of mitral valve prolapse has been found in Graves' disease and a common autoimmune etiology has been suggested for both disorders. We investigated the prevalence of mitral valve prolapse in 87 patients with autoimmune chronic lymphocytic thyroiditis, 50 patients with nongoitrous hypothyroidism and 111 healthy control subjects. Mitral valve prolapse was found in 16.09% of patients with chronic lymphocytic thyroiditis compared to 6 and 5.4% in nongoitrous hypothyroidism and normal controls, respectively. The result is statistically significant, p less than 0.02, and confirms that the prevalence of mitral valve prolapse is significantly increased in patients with autoimmune disorders of the thyroid gland, when compared to normals and nonautoimmune conditions.

Adult↗
PubMed1987

Acute tumour lysis syndrome with extreme metabolic abnormalities.

Tumour lysis syndrome, manifested by various metabolic derangements, is a known complication after treatment of some lymphoid malignancies. A patient is reported with acute lymphocytic leukaemia who developed a tumour lysis syndrome following intensive chemotherapy. All the known complications of the syndrome were present in the most severe form--hyperuricaemia of 1.44 mmol/l, hyperphosphataemia of 7.7 mmol/l with acute oliguric renal failure and extreme hyperkalaemia of 9.8 mmol/l with electrocardiographic changes. This life-threatening condition did not respond to conservative measures and the patient recovered only after haemodialysis.

Adult↗
PubMed1987

Recurrent pulmonary atelectasis as a manifestation of familial Mediterranean fever.

Recurrent attacks of pulmonary atelectasis were the leading sign of familial Mediterranean fever in a young man of Jewish-Georgian extraction. His mother suffered from the more common manifestations of the disease. Treatment with colchicine caused a complete disappearance of his attacks. However, when challenged by discontinuing colchicine therapy for eight days, another, documented attack of pulmonary atelectasis occurred. To our knowledge, this is the first case of familial Mediterranean fever presenting with recurrent pulmonary atelectasis.

Adult↗
PubMed1985

Mitral valve prolapse in hyperthyroidism of two different origins.

The prevalence of mitral valve prolapse was investigated in 126 patients with hyperthyroidism due to Graves' disease or toxic nodular goitre and that of hyperthyroidism in 64 patients with mitral valve prolapse. One hundred and eleven asymptomatic healthy subjects comprised a control group. The patients with hyperthyroidism were divided into those with Graves' disease and those with toxic nodular goitre. Of the group as whole, 12 (9.5%) patients had mitral valve prolapse compared with six (5.4%) in the control group, but the difference was not statistically significant. The prevalence of mitral valve prolapse in the patients with toxic goitre was also not significantly different from that in the controls. When the prevalence in the group with Graves' disease was compared with that in the control group (16.3% vs 5.4%) the difference was significant. Only one patient with mitral valve prolapse had hyperthyroidism.

Adult↗
PubMed1985

Primary fibroxanthosarcoma of the kidney presenting as fever of unknown origin.

Fibroxanthosarcoma is a tumor of soft tissues, mainly effecting the extremities, mediastinum and retroperitoneum. Primary fibroxanthosarcoma of the kidney is extremely rare and has been described in only 4 cases in the past. We present an additional patient, presenting with continuous spiking fever, with rapid deterioration of her condition due to widespread metastases and death within 4 months.

Female↗
PubMed1984

Coumadin-induced skin necrosis.

Two women developed coumadin-induced skin necrosis. A 16-year-old woman sustained necrosis on the leg after a single dose of the drug, and a 59-year-old woman developed gangrene of most of her left breast.

Adolescent↗