Biomedical subjects

Y Hashida

Publications and source records attributed to Y Hashida.

39 records · Page 3Linked to original sources

PubMedDate not supplied

Histopathology of otitis media in infants with cleft and high-arched palates.

The middle ear and the bony and cartilaginous portions of the eustachian tube (ET) were studied histopathologically in 20 temporal bones from 19 infants, aged 45 minutes to 12 months. Otitis media (OM) was observed in 17 of 20 bones, and 16 bones with OM had an effusion. Otitis media was more severe in the ears of cleft palate infants compared to those with high-arched palates. Inflammation was present in the bony portion of the ET in 15 of 17 temporal bones with OM, but appeared to be less marked than that present in the middle ear. In addition, inflammation of the cartilaginous portion of the ET appeared to be less severe than in its bony portion. Inflammation of the middle ear and the ET appeared to be more pronounced in older infants, particularly in those with cleft palates.

Cleft Palate↗

PubMedDate not supplied

Electron microscopic demonstration of viral particles in sudden infant death syndrome.

Viral particles consistent with adenovirus were demonstrated in the intranuclear inclusion bodies of the intestinal epithelial cells in a 3 1/2-month-old girl who died of sudden infant death syndrome (SIDS). The particles were demonstrated by electron microscopy using a routine hematoxylin--eosin-stained section. Although viral infection is known to contribute to the pathogenesis of SIDS, this is the first case of SIDS in which viral inclusion bodies have been demonstrated in the intestinal epithelial cells by light and electron microscopy.

Adenoviridae Infections↗

PubMedDate not supplied

Pancreatic pathology in trisomy 13: specificity of the morphologic lesion.

Pancreases from 8 patients with trisomy 13 were studied. Ectopic splenic tissue was present in 6: 3 had accessory spleens and ectopic splenic tissue embedded in the pancreas, one had intrapancreatic splenic tissue without an accessory spleen, and one had an accessory spleen without intrapancreatic splenic tissue. The intrapancreatic splenic tissue was multiple, generally poorly or nonencapsulated, and contained pancreatic acini, islets of Langerhans, and ducts lined by tall columnar epithelium with goblet cells. The rest of the pancreas in these and other cases of trisomy 13 had microcyst formation and focal proliferations of small ducts similar to those seen in the splenic tissue. This constellation of features appears to be distinctive of trisomy 13.

Abnormalities, Multiple↗