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Y Hiss

Publications and source records attributed to Y Hiss.

33 records · Page 2Linked to original sources
PubMed1986

Sarcoidosis of the penis: report of a case.

We report a case of sarcoidosis identified histologically as the cause of chronic painful erythematous induration of the penis with several subcutaneous nodules and cutaneous ulceration. The lesions improved in response to topically applied corticosteroids but they reappeared later and persisted despite treatment. We suggest that sarcoidosis, although rare, should be considered in the differential diagnosis of any chronic lesion involving the penis in adults.

Humans↗
PubMed1986

Does prolonged use of diphenylhydantoin predispose to pulmonary sarcoidosis?

We describe 3 patients with epilepsy who developed sarcoidosis, stage I, while being treated with diphenylhydantoin for prolonged periods. We are unaware of such an association in the literature. However, in the light of the current knowledge about the adverse immunologic reactions that may be caused by diphenylhydantoin and the altered immunological state described in sarcoidosis, we recommend physicians to look for and report on similar cases in order to assess possible cause and effect relationships between the two.

Adult↗
PubMed1985

Sarcoidosis and Hashimoto's thyroiditis--a chance occurrence?

We present a case of pulmonary sarcoidosis associated with Hashimoto's thyroiditis. This association has been reported previously and may be purely coincidental. However, in light of current knowledge about the immunoregulatory defects postulated for sarcoidosis and for Hashimoto's thyroiditis, three other possibilities that may explain this association in our patient, are discussed.

Aged↗
PubMed1985

Hemoptysis in sarcoidosis.

We describe 4 previously healthy patients with non-cavitated pulmonary sarcoidosis, whose presenting symptom was hemoptysis. Despite the presence of pulmonary involvement in about 90% of patients with sarcoidosis, hemoptysis as the presenting symptom is very rare and was described previously, to our knowledge, in only 5 patients.

Adult↗
PubMed1985

Pulmonary sarcoidosis presenting with unusual roentgenographic manifestations.

Chest roentgenograms of 85 Jewish patients with biopsy-proven pulmonary sarcoidosis were reviewed. In 25 cases (29%), the initial chest roentgenogram showed one of the following unusual manifestations: large pulmonary nodules in 11, an acinar pattern in 10, right hilar lymphadenopathy in 3 and a large pericardial effusion in one patient. Diagnostic biopsy specimens were obtained by an open lung biopsy in 13 patients, by anterior mediastinoscopy in 4, by transbronchial lung biopsy in 3, by skin biopsy in 3 and by liver and splenic tissue examination in 2 patients. Complete roentgenographic resolution occurred only in 4 out of 20 patients who were followed for more than two years (20%), but the majority of them (83% - 15 out of 18 symptomatic patients), improved clinically irrespective of corticosteroid administration. One patient died in the course of follow-up from a cause attributed to sarcoidosis (5% - one out of the 20 patients who were followed for more than two years).

Adrenal Cortex Hormones↗
PubMed1978

Corpora amylacea in mesothelioma of the atrioventricular node.

Rounded or polyhedral, acellular, dense lamellated structures were seen within gland-like spaces in a case of atrioventricular mesothelioma. These structures exhibited many of the histochemical characteristics of amyloid, viz., pink colour with green birefringence and bright red fluorescence with alkaline Congo red; ortochromasia and red birefringence with standardised toluidine blue; positive DMAB-nitrite and diazotisation coupling reactions and spontaneous autofluorescence. It is suggested that these bodies are derived from spontaneous assembly or polymerisation of microfibrils of desquamated cells lining the cystic spaces of the tumour as occurs in prostatic corpora amylacea. The peculiar intramyofibre proliferation of tumour cells in the peripheral part of the tumour suggests that viable tumour cells can penetrate, survive and proliferate within atrial or nodal myofibres leaving an intact sarcolemmal sheath. The slow tumour cell growth and the successive degeneration of central tumour cells may explain the tubular and/or glandular pattern constantly seen in this tumour.

Aged↗
PubMed1978

"Pseudomelanoma" in a keloid.

A pigmented lesion resembling a superficial spreading malignant melanoma appeared in keloidal scarring resulting from partial excision of three closely set intradermal and compound nevi. Complete excision of nevi when feasible is recommended as the wisest course to obviate future uncertainty.

Adult↗
PubMedDate not supplied

Frequent apoptosis in human kidneys after acute renal hypoperfusion.

BACKGROUND/AIMS: Apoptosis, a form of cell death characterized by DNA fragmentation and minimal inflammation, is induced by intrarenal hypoxia in rats. The objective of this study was to test whether apoptosis participates in human acute renal injury. METHODS: We examined kidneys obtained from autopsies of 40 patients following hemodynamic compromise and from 9 controls following sudden death. Nuclear DNA fragmentation was assayed by in situ 3' end labeling (TUNEL stain) and compared to histological findings. RESULTS: DNA fragmentation along renal tubular cells was observed in 23 (57%) of the study patients but in none of the controls (p < 0.005). Acute tubular necrosis was seen by formal histology in 27% of the patients and correlated with clinical acute renal dysfunction, while DNA fragmentation did not. CONCLUSION: DNA fragmentation often occurs after renal hypoperfusion and does not imply renal failure. Apoptosis may participate in the adaptive response of the kidney to hypoxia.

Acute Kidney Injury↗