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Biomedical subjects

Y Horowitz

Publications and source records attributed to Y Horowitz.

At least 19 recordsLinked to original sources

Urinary tract infection: is there a need for routine renal ultrasonography?

AIMS: To assess the yield of routine renal ultrasound (RUS) in the management of young children hospitalised with first uncomplicated febrile urinary tract infection (UTI). METHODS: All children aged 0-5 years who had been hospitalised over a two year period with first uncomplicated febrile UTI in a medium size institutional regional medical centre were included. Children with known urinary abnormalities and/or who had been treated with antibacterial agents within seven days before admission were excluded. All included children underwent renal ultrasonography during hospitalisation and voiding cystouretrography (VCUG) within 2-6 months. The yield of RUS was measured by its ability to detect renal abnormalities, its sensitivity, specificity, and positive and negative predictive values for detecting vesicoureteral reflux (VUR), and by its impact on UTI management. RESULTS: Of 255 children that were included in the study, 33 children had mild to moderate renal pelvis dilatation on RUS suggesting VUR, of whom only nine had VUR on VCUG. On the other hand, in 36 children with VUR on VCUG the RUS was normal. The sensitivity, specificity, positive predictive value, and negative predictive value of abnormal RUS for detecting VUR were 17.7%, 87.6%, 23.5%, and 83.2% respectively. In none of the patients with abnormal RUS was a change in the management at or following hospitalisation needed. CONCLUSION: Results show that the yield of RUS to the management of children with first uncomplicated UTI is questionable.

Bacterial Infections↗

Investigation of the emission spectra of LiF:Mg,Ti (TLD-100) during thermoluminescence.

The thermoluminescence (TL) of LiF:Mg,Ti has been studied using a high resolution CCD spectrophotometer, which simultaneously measures the emission intensity and the emission spectrum as a function of sample temperature. Computerised deconvolution was used to resolve the emission spectrum into individual Gaussian bands and the TL glow curve into glow peaks. Correction for spectral response and non-linear changes in dispersion were taken into account in the evaluation of the emission spectra. The emission spectra of all TL glow peaks following 200 Gy beta irradiation were found to consist of a common set of five emission bands at 2.49 eV, 2.64 eV, 2.84 eV, 3.1 eV and 3.59 eV, of which the 2.95 eV and 3.59 eV bands have not been previously observed at these dose levels. The band characteristics (E, deltaE) are not sample temperature or dose dependent indicating that the same LCs or the same single centre with several excited states are common to all the glow peaks. The relative intensities of the emission bands do. however, change as a function of readout temperature and dose, a behaviour that could be connected to a temperature and dose dependent perturbation between spatially coupled TCs and LCs.

Beta Particles↗

[Salmonella virchow sacroiliitis and bacteremia in a child].

A 2.5 years old girl was admitted because of high fever and limping that appeared two days after she had trauma to her right leg. Bone scan demonstrated increased uptake in the right sacroiliac joint, and CT demonstrated right sacroiliitis. Salmonella vircow was isolated from the blood culture. The patient recovered after a five weeks course of intravenous antibiotics. Salmonella sacroiliitis in children is rare, and only seven cases have been reported in the English literature in the last 40 years. We reviewed the literature dealing with pathophysiology diagnosis therapy and outcome of this infection.

Anti-Bacterial Agents↗

[Thrombocytopenic purpura as sole manifestation of brucellosis in children].

Thrombocytopenic purpura associated with brucellosis has rarely been described in children. The thrombocytopenic purpura is usually part of the array of manifestations of brucellosis, such as fever, malaise, arthralgia, arthritis, hepatosplenomegaly and lymphadenopathy. We describe a 4-year-old girl in whom severe thrombocytopenic purpura was the only manifestation of brucellosis and resolved after appropriate antibiotic therapy. We conclude that brucellosis should be included in the differential diagnosis of thrombocytopenic purpura in areas endemic for brucellosis, and when there is a history of exposure to infected food products.

Anti-Bacterial Agents↗

Hallway medicine: prevalence, characteristics and attitudes of hospital physicians.

BACKGROUND: Hallway medicine is an integral part of physicians' medical culture, but little is known about it. OBJECTIVE: To characterize the practice of hallway medicine among hospital physicians, both as providers and consumers. METHODS: We conducted a survey of 112 randomly chosen hospital physicians at the Soroka Medical Center in Beer Sheva, Israel between November 1997 and May 1998. A self-administered 39-item questionnaire was used that included sociodemographic data, the extent to which hallway medicine is practiced, and satisfaction from and attitudes to it. RESULTS: Of the 112 selected physicians, 111 responded (99.1%). Of these, 91 (82%) had been asked by their colleagues to provide hallway medicine. Most of them (91%) agreed because of "willingness to help," because "it's unpleasant to refuse," or "it's the acceptable thing to do." Most of the requests (72%) were unscheduled and time consuming (41% up to 10 minutes and 21% more than 20 minutes). Records were kept in only 36% of the cases and follow-up in 62%. Physicians who provided hallway medicine were also consumers of it (P < 0.001), based on personal acquaintance, time saved and easy accessibility. In general, the attitude to hallway medicine was negative (54%) or ambiguous (37%). Most requests for hallway medicine were made to Israeli-trained physicians, surgeons or gynecologists, and senior physicians. CONCLUSIONS: Hallway medicine is practiced frequently among hospital physicians. A formal organization of health care service within medical centers might provide physicians with better medical care and reduce potential ethical, medical, legal, psychosocial and economic problems.

Adult↗

[Gradenigo syndrome and cavernous sinus thrombosis in fusobacterial acute otitis media].

In this era of antimicrobial medication, intracranial complications following otitis media are rare. We present a 5-year-old boy who suffered from petrositis (Gradenigo syndrome) and cavernous sinus thrombosis as combined complications of acute otitis media caused by fusobacteria. The diagnosis was made using imaging methods suited to the various structures of the skull. Cure was achieved by prolonged conservative treatment with antibiotics, with gallium scan for evaluation of the bone inflammation.

Cavernous Sinus↗

Interstitial cell (Leydig) tumor in an eland (Taurotragus oryx).

We observed an interstitial cell tumor in an 18-mo-old captive eland bull (Taurotragus oryx) in Tel Aviv, Israel. The histological description of the tumor in the eland was similar to that described in cattle; however, the appearance of a moderate amount of lipid vacuoles in the cytoplasm of the neoplastic cells was uncharacteristic for bovine interstitial cell tumors. The eland also had clinical signs of gynecomastia.

Animals↗