Biomedical subjects

Y Ibuchi

Publications and source records attributed to Y Ibuchi.

8 recordsLinked to original sources

PubMed2004

Human Kluver-Bucy syndrome following acute subdural haematoma.

We present a rare case of complete human Kluver-Bucy syndrome (KBS) following recovery from transtentorial herniation caused by acute subdural haematoma (ASDH). A 17-year-old right-handed high school boy got into stupor within five minutes after 3-rounds of sparing at boxing. Emergency computed tomographic (CT) scan showed right cerebral hemispheric ASDH, which was evacuated following intentional decompressive craniectomy. After recovery of consciousness, he developed emotional changes (placidity with loss of normal fear and anger), psychic blindness, aberrant sexual behaviour, excessive oral tendencies, increased appetite, and hypermetamorphosis in order of mention, which were observed with waxing and waning from 17th to 28th hospital day. Peri-operative CT scaning and magnetic resonance imaging showed lesions of the right temporal lobe and right-dominant orbitofrontal regions including bilateral rectal and medial orbital gyri, and the intact left temporal lobe. Two pathogeneses can be thought of and the whole picture of KBS following ASDH can arise even though one (left in this case) temporal lobe is preserved, 1) in which associated orbitofrontal lesions of the frontal lobes may correlate with occurrence of KBS, or 2) cerebral blood hypoperfusion of both temporal lobes due to increased intracranial pressure and/or compression of both posterior cerebral arteries at the edge of the tentorium cerebelli occurs.

Adolescent↗

PubMed2004

Ruptured de novo intracranial aneurysms.

OBJECTIVE: We describe the actual state of ruptured de novo intracranial aneurysms to contribute to a guideline of follow-up for the patients with treated intracranial aneurysm. METHODS: The authors retrospectively investigated 12 cases drawn from 483 consecutive cases of aneurysmal subarachnoid hemorrhage at our institute over a period of 22 years, in which a previously undemonstrated (hence "de novo") intracranial saccular aneurysm formed and ruptured after successful treatment of a prior aneurysm. FINDINGS: The 12 cases constitute 2.5% of the 483 patients who left our hospital alive. Eleven cases were females and one was a male with a mean age of 55.7 years (range 29-75) at the first subarachnoid haemorrhage (SAH) and an interval between the first and the second rupture of 10.7 years (range: 2.6-23.8, standard deviation: 6.86, 95% confidence interval: 6.39-15.1). Four cases did not have risk factors such as hypertension, family history, smoking, multiple aneurysms, and moyamoya disease. None of these ruptured de novo aneurysms was at the same location as the original lesion. One-third (4 cases) of the de novo lesions in our series were found on the opposite side to each prior lesion. INTERPRETATION: For not only young but also elder patients with a treated aneurysm (from the fifth decade to the sixth), especially for women, late angiography or alternative modalities of less-invasive examination should be considered. To detect de novo intracranial aneurysms before rupture, the search for a de novo aneurysm should be performed within 6.39 years after a previous examination that shows an aneurysm to be nonexistent, in view of the 95% confidence interval of the mean time to de novo aneurysmal rupture (6.39-15.1 years). If applied this survey, 75% (8 cases of 12 cases) of our de novo aneurysms would be detected before rupture.

Adult↗

PubMed1995

Cranioplasty with split-thickness calvarial bone.

Cranioplasty with autogenous split-thickness calvarial bone was performed in 10 patients. Follow-up for a mean of 19 months (range 2-43 mos) showed satisfactory protection of the brain and cosmetic reconstruction. No serious complication was seen except in one patient with postoperative epidural abscess. Split-thickness calvarial bone graft is recommended in patients with previous infection or high risk of infection, in poorly vascularized recipient sites resulting from multiple operations or irradiation, and in younger patients aged more than 7 years.

Adolescent↗

PubMed1993

[A case of distal aneurysms of bilateral posterior inferior cerebellar arteries].

A case of aneurysms of bilateral distal posterior inferior cerebellar arteries (PICAs) is reported. A 61-year-old man experienced a sudden onset of headache and nausea and was admitted to a hospital immediately. His neurological examination showed no abnormalities, but headache and nausea continued in spite of conservative treatment. The patient was referred to our hospital two days after the onset and the neurological examination revealed slight dysmetria of the right upper extremity. A computed tomography (CT) scan demonstrated a round and heterogeneous high density mass at the cerebellar vermis and some blood coagula at the fourth ventricle and vermis. Angiography showed two aneurysms of the bilateral distal PICAs: The right aneurysm was at the cortical segment and the left one was at the telovelotonsillar segment. The patient underwent a suboccipital craniectomy and both aneurysms were clipped successfully. Sleepiness and headache continued postoperatively due to hydrocephalus. After ventricular drainage he soon recovered without having V-P shunt and was discharged with no neurological deficits. Aneurysms of bilateral distal PICAs are very rare and only three cases have been reported in the literature. The etiology, clinical symptom, CT finding and prognosis in the literature reviewed were briefly discussed.

Cerebellar Diseases↗

PubMed1989

Formation of crystals of the insecticidal proteins of Bacillus thuringiensis subsp. aizawai IPL7 in Escherichia coli.

Escherichia coli JM103 cells harboring expression plasmid pTB1 or pKC6 synthesized the 130- and 135-kilodalton insecticidal proteins, respectively, of Bacillus thuringiensis subsp. aizawai IPL7, and both products accumulated as cytoplasmic inclusion bodies. Amorphous inclusions which contained contaminating proteins, together with the corresponding insecticidal proteins, were formed in cultures at 37 degrees C, but bipyramidal crystals practically free of contaminants were observed at 30 degrees C. Although 9.8% of the amino acids were substituted between these two proteins, both protein crystals had the same shape as those of the parental B. thuringiensis strain, which produced both proteins.

Bacillus thuringiensis↗

PubMed1989

[Progressive mental deterioration after radiotherapy in adult patients with brain tumors].

We report a study on changes of mental function in twenty five adult patients with cerebral low-grade gliomas after radiotherapy. None of them had shown mental deterioration before radiotherapy nor tumor recurrence after radiotherapy. Radiation was given at a dose of 48 to 78 Gy (mean: 54.2 Gy). Patients were assigned for mental functional levels according to Karnofsky performance scale (KPS) after radiotherapy. Ten patients (40%) were normal. Seven patients (28%) showed moderate disabilities and 8 (32%) severe disabilities. The median interval time from radiotherapy to the onset of mental deterioration was 2.5 years in the moderate group and 1.6 years in the severe group. CT findings in severe group demonstrated severe brain atrophy and diffuse low density in the white matter after radiotherapy. The risk factors responsible for progressive mental deterioration after radiotherapy may be radiation site and size (whole frontal lobe), total dose (over 60 Gy) and patients age at the time of radiotherapy (over 60 yrs).

Adult↗

PubMed1984

Two cases of dural arteriovenous malformation occurring after intracranial surgery.

The occurrence of post-operative dural arteriovenous malformation (AVM) has rarely been proved angiographically. The authors report two such cases: in one, a pure dural AVM was located in the region of the cavernous sinus and in another a mixed pial and dural AVM was found in the posterior fossa. The literature about pathogenesis is reviewed.

Brain Diseases↗

PubMed1981

Fenestration of the anterior cerebral artery.

Three cases of angiographically demonstrated fenestration of the anterior cerebral artery are reported. Fenestration occurred at the medial half of the horizontal segment of the anterior cerebral artery in all cases. Its embryology and clinical significance are briefly discussed, and the anatomical and radiological literature on fenestration of the anterior cerebral artery is reviewed.

Adult↗