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Y Imate

Publications and source records attributed to Y Imate.

At least 19 recordsLinked to original sources
PubMed2002

Prenatal diagnosis of congenital epulis: a case report.

Congenital epulis or congenital granular cell tumor, is a benign tumor that has rarely been diagnosed prenatally. We report a case of a large congenital epulis diagnosed at 26 weeks of gestation that increased in size during gestation. Color and power Doppler ultrasound examination showed marked blood flow in the tumor. The tumor could be resected completely following Cesarean section and histologically examined. We discuss the prenatal diagnosis and histogenesis of congenital epulis.

Adult↗
PubMed2001

Amplification of 3q26 approximately qter correlates with tumor progression in head and neck squamous cell carcinomas.

Biological characteristics of malignant tumors including head and neck squamous cell carcinoma (HNSCC) are greatly affected by genetic alterations. However, the relationship between chromosomal aberrations and pathologic tumor stage in HNSCC has not been elucidated. In 32 patients, DNA sequence copy number aberrations (DSCNA) were surveyed by comparative genomic hybridization (CGH) combined with a microdissection method. The average number of DSCNA was 15.3 per tumor and increased with tumor stage (P<.05). DNA copy number gain was detected at 3q26 approximately qter in 29 tumors (91%), and 13 of these tumors displayed marked DNA amplification. Tumor stage was linked with this amplification (P<.05). The increase in DSCNA and amplification of 3q26 approximately qter are likely to be useful markers for estimating tumor progression in HNSCC.

Adult↗
PubMed2000

Relationship between cytogenetic aberrations by CGH coupled with tissue microdissection and DNA ploidy by laser scanning cytometry in head and neck squamous cell carcinoma.

BACKGROUND: The relationship between DNA sequence copy number aberrations (DSCNAs) and DNA ploidy in head and neck squamous cell carcinomas (HNSCCs) is still controversial. Materials and Methods We analyzed DSCNAs by comparative genomic hybridization (CGH) combined with microdissection and DNA ploidy by laser scanning cytometry (LSC) in 18 surgically removed HNSCCs and compared the data. RESULTS: Copy number increases were most frequently observed on chromosomes 3q (16 cases), 8q (13 cases), and 12p (11 cases). Copy number decreases were observed on chromosome 3p (14 cases). LSC revealed DNA aneuploidy in 10 of the 18 cases. All DNA aneuploid tumors exhibited gain or amplification of DNA copy number at 12p11-12.1, whereas gain of DNA copy number was found in only 1 of 8 diploid tumors. DSCNAs were more frequent in DNA aneuploid tumors than in diploid tumors (P < 0.005). CONCLUSIONS: The present observations indicate a close relationship between DSCNAs and DNA ploidy in HNSCCs.

Aged↗
PubMed2000

[Second reconstructions after failure of free-tissue transfer in the head and neck region].

A retrospective study was performed on 74 patients seen in our hospital between 1990 and 1999 who underwent head and neck reconstructive surgery involving a free flap. Reconstructive surgery was unsuccessful in 5 cases (6.8%). A pedicled myocutaneus flap was used in two cases for the second reconstruction attempt, while a second free flap (jejunum) was used in two other patients. In these cases, a bilateral neck dissection was performed prior to the second free flap reconstruction and neck infection was found. The head and neck artery and vein were unsuitable as recipient vessels in the second operation. Instead, the cephalic vein was used as a source of vein grafts and as a recipient vein.

Adult↗
PubMed2000

[A case of synchronous cervical lymph node metastases from testicular and thyroid cancers showing mixed response to chemotherapy].

We report a case of synchronous presentation of thyroid cancer and testicular seminoma with lymph node metastasis. A 37-year-old man presented with right scrotal swelling and multiple lymph node swelling. We performed right radical orchiectomy, and histological examination revealed a seminoma of the testis. After systemic work-up for staging, we diagnosed the patient with multiple lymph node metastasis of the seminoma, and administered three cycles of bleomycin, etoposide, and cisplatin (BEP) therapy. Although the chemotherapy was very effective for the retroperitoneal and left cervical lymph node metastases, the right cervical tumor did not change. Retroperitoneal lymphadenectomy combined with right cervical lymph node dissection and hemi-thyroidectomy were performed on September 8, 1998. Pathological examination of the thyroid revealed papillary thyroid cancer and its right cervical lymph node metastasis. There was no evidence of viable cancer cells from either of the primary cancers in the retroperitoneal lymph node. Unresponsiveness to chemotherapy for metastatic lesions from testicular cancer might be a useful clue to detect primary tumors of other origins.

Adult↗
PubMed1995

Central disorders in vestibular neuronitis.

Between 1972 and 1993 equilibrium and audiological examinations were made on 73 patients who had been diagnosed to suffer from vestibular neuronitis. In 23 of these patients, central nervous disorders (CND) were suspected from the result of tests of positional and positioning nystagmus, smooth pursuit, optokinetic nystagmus or auditory brainstem response. In this group of patients the frequency of associated disorders and vertiginous symptoms (dizziness) was statistically higher than in the remainder 50 patients who did not have CND. In the CND group the time interval between the onset and improvement or disappearance of all vertiginous symptoms, nystagmus and canal paresis was longer than in the non-CND group.

Adolescent↗
PubMed1995

Enhanced MRI in patients with vestibular neuronitis.

Recent advances in magnetic resonance imaging (MRI) have demonstrated facial nerve enhancement in facial nerve palsy and cochlea enhancement in sudden deafness. However, no report has described the findings of enhanced MRI in vestibular neuronitis. Eight cases of vestibular neuronitis were studied with enhanced MRI. We did not detect any enhanced lesions of the vestibular nerve or ganglion. So far, as the present conditions of MRI are concerned, it is difficult to detect any enhancement in the vestibular nerve and ganglion. Further study will be required to evaluate the suitability of MRI for vestibular neuronitis.

Adult↗
PubMed1993

Vestibular neuronitis: epidemiological survey by questionnaire in Japan.

An epidemiological survey on vestibular neuronitis in Japan was conducted by means of a questionnaire filled in by major neuro-otology clinics (otolaryngologists) during 1988-1990 (3 years). The diagnostic criteria of vestibular neuronitis settled on in 1986 by the Standardization Committee of the Japan Society of Equilibrium Research were applied. Gross analysis of questionnaire answers showed that i) there was no sexual difference, ii) the peak of age distribution was between 40-50 years, iii) about 30% of all cases had had common colds prior to the disease, the rate being highest among children below 10 years, iv) disappearance of positional and positioning nystagmus appeared in about 60% of all cases within 3 months, and that v) caloric CP was observed in about half of the cases at the follow-up test. Progress was not as favorable when compared to previous studies.

Adolescent↗
PubMed1993

Vestibular compensation in vestibular neuronitis: evaluation of positional nystagmus and caloric nystagmus.

We evaluated the vestibular functions, especially for positional nystagmus and caloric nystagmus, in 43 cases of vestibular neuronitis for long periods after its onset. It is shown that in the cases of vestibular neuronitis that were studied more than 10 years after the onset of the disease, the completed vestibular compensation changed or the vestibular compensation was still incomplete.

Caloric Tests↗
PubMed1993

Vestibular neuronitis in children.

Seventeen cases of vestibular neuronitis in children, including 11 cases from the questionnaires of an epidemiological survey in Japan and 6 patients in our clinic, were examined. Sex and age distribution was 11 males and 6 females, ranging in age from 3 to 15 years. Bilateral and recurrent cases were not encountered. Fifty-three percent of children had had a preceding episode of an upper respiratory tract infection and this ratio was higher than that in adults. The etiology of vestibular neuronitis is probably many-faceted, but it is thought that upper respiratory tract infections play an important role especially in children. Vertiginous symptoms had almost subsided among children at the last visit. However, among adults, 24% of patients felt persisting unsteadiness. The disappearance of positional and positioning nystagmus was observed in 71% of children at the last visit. Caloric CP failed to recover in only 14% of all cases who were re-examined. As shown in this study, the prognosis in children is better than in adults for nystagmus and caloric response. The results of this study thus indicate that not only central compensation but also recovery of the peripheral vestibular function is more effective for bringing recovery from the vestibular disorder in children than in adults.

Adolescent↗
PubMed1993

Vestibular neuronitis in aged patients: results from an epidemiological survey by questionnaire in Japan.

An epidemiological survey of vestibular neuronitis in Japan was done using a questionnaire. Answer sheets were obtained from 619 patients with vestibular neuronitis. In order to evaluate data from aged patients, 74 cases were singled out. The following results were obtained: i) There was no sexual difference and no laterality of affected side; ii) There was no case of bilateral vestibular neuronitis; iii) Ten cases were reported as recurrent. Aged patients had a relatively high rate of recurrence; iv) About 10% of 74 cases had had an upper respiratory tract infection, and this rate was lower than that for patients under 65 years of age; v) Thirty-five cases had complications. Hypertension was the most common complication; vi) The caloric test was re-used in 28 cases. The continued existence of caloric CP was observed in 23 cases upon re-examination.

Aged↗
PubMed1993

Vestibular compensation in vestibular neuronitis. Long-term follow-up evaluation.

We evaluated vestibular function, especially for positional, head shaking and caloric nystagmus, in 43 patients with vestibular neuronitis, for long periods from the onset. The results suggested that in these cases of vestibular neuronitis, which were studied for more than 10 years after onset of the disease, the disease may still be in the uncompensated stage or may have worsened in the partially compensated stage.

Adolescent↗
PubMed1991

Analysis of the fast phase of per-rotatory nystagmus.

We studied the relationship between the fast phase velocity and amplitude of per-rotatory nystagmus resulting from constant angular acceleration and deceleration stimulation. The relationship was nonlinear and was best fit to the exponential equation. We established the uppermost point of the data distribution along the resolution curve. In normal subjects the angular rotatory stimulation using a computer-controlled rotatory chair (ROKOS-6) with 5 degrees/s2 rotation was the best among three kinds of angular rotatory stimulation (1.2 and 5 degrees/s2). Compared to peripheral vestibular disorder the uppermost point of nystagmus had a tendency to be larger in amplitude in some cases with central vestibular disorder. In many cases with sudden deafness the same tendency was seen.

Acceleration↗
PubMed1991

[Localized amyloidosis of larynx. A case report and immunohistochemical study].

A case of the localized laryngeal amyloidosis was reported. The patient was a 51-year-old female who complained of hoarseness for about a year. Pathological study on the biopsy specimen taken from both the subglottic area under laryngeal microsurgery showed the deposit of amyloid. Laryngeal microsurgery showed the deposit of amyloid at bilateral subglottic area. Electron microscopic study disclosed a typical amyloid fibrillar structure. Amyloid protein, in this case, was confirmed as protein A lambda appeared through the potassium permanganate treatment and immunoperoxidase technique (ABC method).

Amyloid↗
PubMed1989

Vestibular neuronitis. Pathogenesis in the view of virological study of CSF.

Cerebrospinal fluid (CSF) samples from 15 patients with vestibular neuronitis were virologically examined and analyzed, and compared to those from 16 patients with Hunt's syndrome. The results were as follows: The CSF protein in vestibular neuronitis showed an increase, beginning about two weeks after the onset of vertigo, while the cell count remained normal. The CSF protein in Hunt's syndrome rose, but its progress was different from that in vestibular neuronitis. In both diseases, the increase in CSF protein seemed to be due to protein originating in the blood; the increase was probably caused by a disorder of the blood-CSF barrier. There was no direct evidence of an increase in IgG nor viral antibody titers in the CSF in vestibular neuronitis. In cases of Hunt's syndrome with CSF pleocytosis, intrathecal IgG synthesis was detected. It might be possible that HSV or EBV infection can be confirmed serologically in some cases of vestibular neuronitis and that, in those cases, pathogenesis of vestibular neuronitis is similar to that of Hunt's syndrome.

Adolescent↗
PubMedDate not supplied

Epithelial-myoepithelial carcinoma of the nasopharynx.

We present a patient with a rare epithelial-myoepithelial carcinoma of the nasopharynx with a typical biphasic histopathologic pattern. Immunohistochemical findings support the concept that the inner cells differentiate to ductal epithelium and the outer cells to myoepithelium. In this patient complete excision of the tumor and reconstruction with a pedicled sternocleidomastoid myocutaneous flap were performed. A DNA diploid pattern from flow cytometric study indicates a favorable prognosis. There was no recurrence nor metastasis for 55 months.

Aged↗