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Biomedical subjects

Y Iyomasa

Publications and source records attributed to Y Iyomasa.

At least 19 recordsLinked to original sources

[A case of membranous obstruction of inferior vena cava at the hepatic associated with hepatocellular carcinoma and liver cirrhosis].

A case of inferior vena cava obstruction at the hepatic portion associated hepatocellular carcinoma with and liver cirrhosis is reported, which was treated with lateral segmentectomy of the liver after transcatheter angioplasty. A 36-year-old male, who had noticed venous dilatation in the abdominal wall and legs from his childhood, visited a doctor complaining of right upper quadrate pain and was diagnosed liver cirrhosis. One year later ultrasonography revealed a liver tumor, which was diagnosed as hepatocellular carcinoma by ultrasonically guided aspiration cytology. Inferior and superior vena cavography revealed complete membranous obstruction of inferior vena cava at the hepatic portion with marked collateral circulation through azygos, hemiazygos and phrenic veins. The caval pressure difference between above and below the obstruction was 16.5 cm H2O. The membranous obstruction was perforated and dilated by transluminal angioplasty using Dotter's balloon catheter. The obstructive segment of inferior vena cava changed into 8mm in diameter after the second angioplasty, and the caval pressure difference between above and below the stenosis decreased to 10 cm H2O. Lateral segmentectomy of the liver was performed. Histopathologic diagnosis was clear cell type hepatocellular carcinoma with liver cirrhosis. Marked postoperative liver damage was observed and transcatheter caval dilatation was performed again. The pressure of inferior vena cava below the stenosis decreased to 8 cm H2O. One year and 8 months after the operation, the patient is healthy without recurrence of cancer.

Adult↗

A study of sequential anastomoses in aortocoronary bypass surgery--internal configuration by the casting injection technique.

Presently, sequential aortocoronary bypass grafting is a widely used method for the revascularization of multiple coronary vessel disease. In this study, the internal configurations of the anastomosed portions were investigated by casting models and the following results were obtained: In crossed side-to-side anastomoses with longitudinal incisions, the anastomosed area for the incised length was larger than in the other anastomosis techniques. Interrupted sutures produced a larger anastomosed area for the incised length than other suture techniques. Crossed side-to-side anastomoses with one longitudinal and one transverse incision resulted in the most frequent reoccurrence of narrowings.

Animals↗

Modified hepatic portal enterostomy for biliary atresia.

Macroscopic and microscopic studies of the portal tract in liver specimens obtained at autopsy from 5 noncorrectable biliary atresia patients were performed. The studies disclosed that major intrahepatic bile ducts had disappeared for variable distances in noncorrectable biliary atresia patients. However, the topographic relationship between intrahepatic bile ducts and blood vessels was just the same as in normal livers. On the basis of these studies, we preformed more extensive portal exploration in order to get closer to the obstructed ends of major intrahepatic bile ducts. Hepatic portal enterostomy was also modified to avoid obstruction of the explored area by the jejunal wall to be anastomosed The results of 7 patients who received the new operation were encouraging with complete loss of jaundice in 6 of 7 patients.

Bile↗

Nonsurgical technique for removal of catheter fragments from the pulmonary artery.

In this report the authors describe a new technique for nonsurgical retrieval of an embolized catheter fragment without free ends in the pulmonary artery using a "forceps with three grasping prongs." This method is extremely promising for retrieval of catheter fragments in the pulmonary artery, especially when the free ends are not accessible.

Adult↗

Fourteen cases of left atrial myxoma with emphasis on related histology.

With the availability of diagnostic ultrasonic equipment, there is an increase in the number of diagnosed cases of left atrial myxoma. Fourteen such patients underwent surgical treatment. One major concern was the possible recurrence of the tumor. Histologic examination revealed that the tumor cells did not invade the muscular layer beyond the layer of elastic fiber adjacent to the endocardium, in all cases. We remove the stalk with the Fossa Ovale when the tumor grows on the Fossa Ovale. When the tumor is attached to the muscular septum or free wall, we remove the stalk with the endocardium and a part of the adjacent myocardial layer. The total resection of the muscular septum may not be necessary as far as the myxoma is concerned.

Adolescent↗

Autopsy study on operative procedure and indication for transposition of the great arteries.

The surgical correction of the transposition of the great arteries (TGA) is divided into three procedures by the methods of switching i.e., (1) intra-atrial, (2) intra-ventricular, and (3) via the great arteries. Arterial correction is considered as an ideal technique physiologically as well as anatomically. With the above in mind, twenty formalin-preserved hearts of TGA were used to carry out the following studies: (1) feasibility of coronary artery relocation, (2) feasibility of switching of the aorta and pulmonary trunk, (3) feasibility of the conduit procedure, and (4) effect of left ventricular hypoplasia. The Jatene operation in which coronary artery relocation was needed proved feasible in 20% of the cases. The Damus-Kaye-Stansel operation seemed feasible in 45% of the cases. Hypoplasia of the left ventricle was suspected in 3 of the cases that belonged to Group 1 according to Kidd's classification.

Female↗

[Case of double primary carcinoma of the lung and ureter].

A 73-year-old man visited our hospital complaining of chest distress in September 1979. A chest X-ray film showed a tumor shadow in the left lung and left inferior lobectomy was performed. The tumor measured 50 X 40 X 30 mm; it was diagnosed as large cell carcinoma. In November 1980 the patient suddenly noticed macroscopic hematuria although there had been no microscopic hematuria at his first visit. Ultrasound-guided percutaneous pyelography confirmed complete obstruction of the left ureter and he underwent left ureteronephrectomy. The papillary tumor, measuring 23 cm, was diagnosed as transitional cell carcinoma.

Aged↗

[Clinical study of diffusion of cefotiam into myocardial tissue].

In 11 patients undergoing open-heart operation, 1 g of cefotiam (CTM) was administered intravenously by bolus technique at the start of operation. Samples of serum were obtained at 30, 60 and 90 minutes following administration. Samples of right atrial appendage tissue and serum were obtained simultaneously at the time of heart cannulation. Antibiotic concentrations of all samples were determined by agar well method using P. mirabilis ATCC21100 as the test organism. The results were as follows: Serum levels of CTM after 30, 60 and 90 minutes were 53.1 +/- 17.6 micrograms/ml (Mean +/- S.D., n = 10), 26.1 +/- 10.4 micrograms/ml (n = 11) and 13.5 +/- 5.5 micrograms/ml (n = 7) respectively. Myocardial tissue levels of CTM after 60 and 90 minutes were 9.4 +/- 4.7 micrograms/g (n = 4) and 4.8 +/- 2.7 micrograms/g (n = 7) respectively. The concentration ratios of the myocardial tissue to serum were 0.36 +/- 0.10 (n = 4) after 60 minutes and 0.35 +/- 0.09 (n = 7) after 90 minutes. CTM can transmigrate from blood to myocardial tissue easily as compared with other cephalosporins. Therefore, CTM, a new broad spectrum cephalosporin, can be considered as one of the highly useful antibiotics for the prevention and treatment of infections following cardiac operation.

Adolescent↗