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Biomedical subjects

Y Jiménez

Publications and source records attributed to Y Jiménez.

15 recordsLinked to original sources
PubMed2002

Lichen sclerosus et atrophicus manifesting with localized loss of periodontal attachment.

Lichen sclerosus et atrophicus (LSA) is a chronic mucocutaneous inflammatory disorder of uncertain aetiology that is clinically characterized by the appearance of well delimited white plaques or papules, preferentially affecting the skin and genitals, and more rarely the oral cavity. We present the case of a woman with LSA limited to the oral cavity in the form of a well delimited, flat whitish lesion affecting the vestibular gingiva of the right upper incisors and left central incisor, and extending towards the vestibular fundus and frenulum of the upper lip. Widening of the periodontal space was observed, with gingival recession and attachment loss limited to these teeth. Local corticosteroid injections caused the mucosal lesion but not the periodontal alterations to resolve. Emphasis is placed on the importance of knowledge of this condition in relation to establishing a diagnosis, and on its periodontal repercussions.

Adult↗
PubMed2002

Oral leishmaniasis in a HIV-positive patient. Report of a case involving the palate.

Leishmaniasis is a parasitic disease caused by a protozoon (Leishmania), with different clinical forms that are endemic in certain countries. The association of this disease in patients who are seropositive to human immunodeficiency virus (HIV) has recently been described. Leishmaniasis can develop in any stage of HIV infection, although the clinical manifestations - and hence the diagnosis - tend to coincide with the periods of maximum immune depression. We present the case of a HIV-positive, ex-intravenous drug abuser (in stage B2 of the CDC, 1992) with concomitant hepatitis C infection who presented with palatinal pain and bleeding for the past 2 months. Exploration revealed a vegetating tumoration of the hard palate. Hematoxylin-eosin and Giemsa staining of the biopsy confirmed the diagnosis of leishmaniasis. The definitive diagnosis was mucocutaneous leishmaniasis (MCL), for a bone marrow aspirate proved negative, and no further lesions could be established. The patient was treated with meglumine antimoniate (Glucantime), followed by improvement of the lesions.

AIDS-Related Opportunistic Infections↗
PubMed2001

[Intraoral non-Hodgkin's lymphoma. Presentation of 4 clinical cases].

The non-Hodgkin lymphomas (NHL) represent an heterogeneous group of malignancies of lymphoreticular histogenesis. In most cases, they initially arise within lymph nodes but so-called extranodal lymphomas are also found. The NHL has low incidence in the oral cavity. It may involve bone and/or soft tissues as a primary or secondary manifestation. We present a review of the literature and four clinical cases of intraoral NHL. The first couple of cases are primary forms, the third one is associated to HIV infection and the last one is an oral presentation as a component of more widely disseminated disease.

Adult↗
PubMed2001

Langerhans' cell histiocytosis restricted to the oral mucosa.

Langerhans' cell histiocytosis comprises a group of disorders with Langerhans' cell proliferation as a common feature. The clinical presentation might be highly varied. Typically, there is bone involvement and, less frequently, lesions might be found in other organs, particularly the lungs, liver, lymph nodes, skin, and mucosae. Lesions limited to the oral mucosa are rare. We describe two patients with unifocal eosinophilic granuloma exclusively limited to the oral mucosa. Triamcinolone acetonide infiltration of a palatal lesion yielded a good result in one patient. Six months later, a similar lesion developed in the mandibular gingival mucosa, but it responded to the same treatment. The lesion in the other patient responded to local radiotherapy.

Female↗
PubMed2001

A new method for continuous monitoring of series resonance frequency and simple determination of motional impedance parameters for loaded quartz-crystal resonators.

A new electronic design for continuous motional series resonant frequency monitoring of loaded quartz crystal resonators is presented. Using this circuit, a low-cost method for a simple determination of equivalent circuit parameters of quartz crystal resonators is described. Measurements made with the proposed system on typical AT cut quartz crystals are in good agreement with those of an Impedance Analyzer.

Letter↗
PubMed2001

An extended Butterworth-Van Dyke model for quartz crystal microbalance applications in viscoelastic fluid media.

An extended Butterworth-Van Dyke (EBVD) model with frequency-independent parameters for the characterization of a resonant compound formed by a quartz crystal in contact with a finite viscoelastic layer contacting a semi-infinite viscoelastic medium is extracted by analysis of the lumped element model. The formulation of the EBVD model is compared with the complete expression of the electrical admittance of the loaded quartz derived from the transmission line model (TLM). Relative deviations between them do not exceed 3% around 1% bandwidth near resonance. An extended Martin & Granstaff's model and an explicit expression for the frequency shift that supposes an extension of Kanazawa's model for viscoelastic media are obtained. An analysis of the errors associated with the extraction of shear parameters of the coating for different materials prove that, to obtain an error less than 5% in the shear parameters determination, the viscoelastic contribution, defined as the relative error in the thickness computed from the frequency shift by Sauerbrey equation, must be greater than a limit that depends on Q, which is defined as the ratio of the shear storage modulus (G') to shear loss modulus (G"). In the materials studied, polymers in the transition range or in the rubbery state with Q = 1 and 10, the viscoelastic contribution must be higher than 15% and 50%, respectively, for a 5% limit error in the shear parameters extraction. A criterion for a practical determination of the appropriate viscoelastic regimes is indicated.

Journal Article↗
PubMed1999

Renal hemodialysis patients: oral, salivary, dental and periodontal findings in 105 adult cases.

OBJECTIVES: A study of the dental, periodontal, oral mucosal and salivary condition of adult patients with chronic renal failure (CRF) receiving hemodialysis (HD). MATERIAL AND METHODS: A total of 105 patients on HD were studied, together with 53 healthy age and sex-matched controls. Indices employed included carious, absent and obturated teeth index (CAO index), plaque index, calculus index and loss of periodontal attachment. Whole and parotid salivary secretions were also measured. RESULTS: The CAO index was not significantly higher among HD patients than controls (14.9 +/- 8.7 vs 13.3 +/- 7.9, respectively; t = 1.1; P = 0.3). However, plaque and calculus indices were significantly higher in HD patients (2.1 +/- 0.8 and 2.3 +/- 0.6, respectively) than controls (1.3 +/- 0.8 and 1.6 +/- 0.9) (P < 0.001). Loss of periodontal attachment was similar in both groups (4.9 +/- 2.5 vs 4.2 +/- 2.5 in the HD patients and controls, respectively) (t = 1.8; P = 0.07). There was no more oral mucosal pathology in HD patients than in controls (chi-square = 5.8; P = 0.3). Stimulated salivary secretion was significantly higher in controls than HD patients for both whole (t = -5.2; P < 0.001) and parotid (t = -2.6; P = 0.01) salivas. CONCLUSIONS: The results show significantly higher plaque and calculus indices and lower salivary secretion among the HD patients than in healthy controls.

Adult↗
PubMed1998

Psychologic factors and oral lichen planus. A psychometric evaluation of 100 cases.

OBJECTIVE: The purpose of this study was to analyze the importance of psychologic factors in patients with oral lichen planus, and attempts were made to identify possible personality features characteristic of patients with oral lichen planus. STUDY DESIGN: The study involved 100 patients with oral lichen planus (group 1) and 50 control subjects (group 2). We applied the following psychometric tests to both groups: Spielberger State-Trait Anxiety Inventory, Cattell Personality Questionnaire 16PF, Hassanyeh Rating of Anxiety-Depression-Vulnerability, Beck Depression Inventory, Raskin Depression Screen, and Covi Anxiety Screen. RESULTS: The patients with oral lichen planus were found to exhibit greater anxiety, as reflected by statistically significant scores with the anxiety tests that were used (Spielberger State-Trait Anxiety Inventory, Cattell Personality Questionnaire 16PF, Hassanyeh Rating of Anxiety-Depression-Vulnerability, and Covi Anxiety Screen). The patients with oral lichen planus likewise exhibited greater depression than the controls in all 3 depression tests applied (Beck Depression Inventory, Hassanyeh Rating of Anxiety-Depression-Vulnerability, and Raskin Depression Screen) and were more vulnerable to psychic disorders on the basis of the PD subscales (vulnerability) of the Hassanyeh questionnaire. Three features (conformity to the group, astuteness, and rebelliousness) defined the personalities of our patients with oral lichen planus, according to the Cattell 16PF questionnaire. Finally, those patients with erosive lichen planus exhibited higher depression scores than patients with nonerosive lichen planus. CONCLUSIONS: Despite the higher anxiety scores observed in patients with oral lichen planus, it was not established that the observed psychologic alterations constitute a direct etiologic factor of oral lichen planus; nor was it established that such alterations are a consequence of oral lichen planus and its lesions.

Analysis of Variance↗
PubMed1998

Preliminary investigation of the association of oral lichen planus and hepatitis C.

OBJECTIVE: The aim of this investigation was to determine if an association exists between hepatitis C virus and oral lichen planus. STUDY DESIGN: Three groups of subjects were selected: 505 patients with hepatitis C virus infection (group 1), 100 patients with oral lichen planus (group 2), and a randomly selected control group (age- and gender-matched) of 100 healthy subjects (group 3). The prevalence of oral lichen planus was determined in groups 1 and 3, and the prevalence of hepatitis C virus infection was established in groups 2 and 3. RESULTS: The prevalence of oral lichen planus was 3.36% (n = 17) in group 1 and 1% (n = 1) in the control group; the prevalence of hepatitis C virus infection was 23% (n = 23) in group 2, and 5% (n = 5) in the control group. No significant differences were observed in the incidence of oral lichen planus in group 1 between those patients who received interferon and those who did not. The 17 patients in group 1 who manifested oral lichen planus and hepatitis C virus infection simultaneously exhibited a marked tendency to have only reticular lesions (70.6%), with involvement of the buccal mucosa in 88.2% of these patients, the tongue in 29.4%, and the gingiva in 11.8%. Analyzing a randomized subgroup of 143 patients from group 1 (subgroup 1) that was matched by age and gender with groups 2 and 3, we found that the incidence of oral lichen planus in patients with hepatitis C virus infection (subgroup 1) was greater than in the control group (5.59% vs 1%), though this was not statistically significant (chi2 = 0.119; p = 0.06). In contrast, group 2 exhibited a statistically significant higher incidence of hepatitis C virus infection (23%) than the controls (5%; chi2 = 0.259, p = 0.0002). CONCLUSIONS: The prevalence of hepatitis C virus infection in patients with oral lichen planus was greater than in the control series. In our opinion this observation warrants the investigation of potential concomitant hepatitis C virus infection in patients with oral lichen planus.

Candidiasis, Oral↗
PubMed1996

Candida biotypes in patients with oral leukoplakia and lichen planus. Candida biotypes in leukoplakia and lichen planus.

Prevalence of yeasts in 35 leukoplakia and 34 oral lichen planus patients was compared with that observed in persons without oral diseases. Serotype and morphotype were determined on Candida albicans isolates. Yeasts were isolated from the oral cavity specimens of 43.7% of the patients. C. albicans (serotype A) was the predominant species (76% in leukoplakia, 88.2% in lichen planus and 60.8% in healthy persons). Sixteen morphotypes were encountered on malt extract agar, being 732, 733, 734, 753 and 754 the most frequently found. Morphotypes SP1N and SP1Y were the most common on Sabouraud-trypheniltetrazolium agar (68.4% of the isolates from leukoplakia and 73.3% from lichen planus, but only 46.6% of the isolates from healthy oral mucosa showed SP1N morphotype). Presence of oral lesions was associated with a marked reduction in the yeast species and C. albicans biotypes, suggesting that C. albicans and particularly some of its biotypes, show a high potential of adaptation to the changes associated with the development of oral leukoplakia and lichen planus.

Adult↗
PubMed1992

A clinical study of 205 patients with oral lichen planus.

Two hundred and five patients with oral lichen planus were divided into two groups: those with only reticular lesions (group 1) and those with atrophic-erosive lesions with or without concomitant reticular lesions (group 2). A comparative study of the two groups showed that the most commonly affected oral location in both was the buccal mucosa. Lesions of the tongue, gingiva, lip, and palate predominated in group 2. Likewise, chronic liver disease and diabetes were more common in the second group, as was extension of the oral lesions (P less than .001).

Aged↗
PubMedDate not supplied

[Angiocentric lymphoma of the palate].

Angiocentric lymphomas are very infrequent neoplasms in our geographical setting. They tend to develop in the oronasal region in the form of necrotic lesions--specifically in the midfacial zone--with a rapid course and poor prognosis. Immunohistochemically, the malignant cells have been shown to correspond to T lymphocytes. In addition, recent research supports the possible role of Epstein-Barr virus as a possible etiological factor. We present the case of a 67 year old man with an ulcerated palatinal lesion of recent appearance that was diagnosed as angiocentric lymphoma by histopathological and immunohistochemical study. Following diagnosis, treatment was provided in the form of 3 cycles of CHOP type chemotherapy and radiotherapy.

Aged↗
PubMedDate not supplied

Pleomorphic adenoma of the palate.

An 82-year-old female with a history of high blood pressure and anorexia. She was referred for a long-evolving, asymptomatic large tumor (3x3 cm) on the right side of the palate (fig 1). The patient was wearing total dentures. Intraoral examination revealed a pediculate tumor of the same color as the adjacent mucosa and presenting a firm consistency. An MRI study (fig 2-3) and biopsy were carried out (fig 4-6).

Adenoma, Pleomorphic↗
PubMedDate not supplied

Dental findings in patients with liver cirrhosis. A study of 100 cases.

A study was made of the dental findings in 100 patients with liver cirrhosis (LC) by examining the number of carious, missing and filled teeth. A significantly greater number of carious and missing teeth were observed in the patients with cirrhosis than in a control group of 50 healthy individuals. In the LC group, caries were found to affect more teeth in those patients with alcohol-induced LC than in those with liver disease of other causes. Finally, no relationship was observed between the number of carious, missing or filled teeth and certain determinations including serum glutamate pyruvate transaminase (SGPT), serum glutamate oxalacetate transaminase (SGOT), alkaline phosphate, platelet number, hepatitis B and C positivity markers, or antinuclear (ANA), antimitochondrial (AMA) or anti-smooth muscle autoantibodies (ASm).

DMF Index↗