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Y Joyeux

Publications and source records attributed to Y Joyeux.

10 recordsLinked to original sources
PubMed1988

[Influence of different types of experimental obesity on resistance of the mouse to infection by Salmonella typhimurium and Klebsiella pneumoniae].

Resistance to infections inducing two types of immune response, humoral and cell-mediated, has been measured in mice after Salmonella typhimurium and Klebsiella pneumoniae inoculation; the animals exhibited different kinds of obesity: genetic, ob/ob and db/db mutants, induced by fat diet or gold thioglucose (aurothioglucose) injection (determining obesity of central origin). Klebsiella infection was aggravated in all types of obesity. Salmonella infection was aggravated in genetically diabetic and dietary-obese mice. The two kinds of genetically obese mice show an important functional decrease in splenic lymphocytes. In contrast, aurothioglucose-obese mice were more resistant than controls.

Animals↗
PubMed1977

Comparative study of macrophage migration in different strains of mice: absence of migration in C3H mice.

In the course of studying the susceptibility of mice to Salmonella infection, we discovered that C3H/HeJ mice differ from other strains in both their susceptibility to infection and their response to prior vaccination. Others have noted the absence of the usual B cell stimulation by LPS in these mice. To investigate the status of delayed hypersensitivity in C3H/HeJ mice, we tried to use the technique of macrophage migration. Under conditions of normal migration for other strains, C3H/HeJ peritoneal and splenic macrophages failed to migrate, thus establishing another differentiating immunological trait for this strain.

Animals↗
PubMedDate not supplied

[Study of X antigen of Salmonella typhi responsible for the production of protective antibody towards chick embryo].

Laboratory animals are not sensitive to human S. typhi strain (O+ Vi+). But the chick embryo is very susceptible to infection by this strain. This property can be used to test protective activity of immuno sera. Several antigenic fractions have been prepared from Ty6S strain (0- Vi+) by washing methods. The " outer layer " of the bacteria is easily removed by NaCl 0,5 M. Injected in rabbits this preparation produces the synthesis of protective antibodies. The active antigen X is spun down with the Vi antigen. The relation of X antigen to Vi antigen is being studied.

Animals↗