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Biomedical subjects

Y Kiryu

Publications and source records attributed to Y Kiryu.

At least 37 records · Page 2Linked to original sources
PubMed1993

Urinary bladder carcinoma producing granulocyte colony stimulating factor (G-CSF): a case report with immunohistochemistry.

A rare case of urinary bladder carcinoma with granulocyte colony stimulating factor (G-CSF) production was reported. In an 83-year-old female, marked neutrophilia in the peripheral blood decreased from 132,500/mm3 to 3,300/mm3 after tumour resection. The tumour was a transitional cell carcinoma. The serum G-CSF level reduced from 238 pg/ml pre-operatively to normal (60 pg/ml) after the operation. Immunohistochemical investigation of the resected tumour with monoclonal antibody specific for G-CSF revealed positive staining in the carcinoma cells, confirming G-CSF secretion.

Aged↗
PubMed1993

A case of appendiceal mucocele showing massive mucous production with concomitant colonic cancer.

A 58-year-old male patient presented with abnormal discharge of 200 ml transparent fecal mucus. Irregular protuberance of the ascending colon into the adjacent ileocecal region was observed by colonofiberscopy, and a cystic lesion in the ileocecal region was suggested by computerized axial tomography. Pale yellowish semitransparent jellied substances were observed exudating from the site of ileocecal resection. The diagnosis established was moderately differentiated colonic adenocarcinoma and a mucocele of the appendix. The mucus discharge disappeared after resection. Biochemical analysis of the mucus suggested the mucocele as a source of the discharged mucus. We report an extremely rare case of mucocele of the appendix that may be related to the cause of mucous stool.

Adenocarcinoma↗
PubMed1993

[Changes in the hypnograms of subjects exposed to repeated truck-passing sounds of 45, 50 and 55 dB (A)].

The effects of traffic noise on sleep were evaluated in an experimental room using recorded truck-passing sounds. Peak sound levels were 45, 50, 55 dB (A) at a frequency of one per hour. The background noise of the exposure night was Leq 32.4 dB (A). The subjects were five male students 22 to 23 years old. The sleep stage of each epoch with a 20-second duration was judged visually based on the criteria of a standardized sleep EEG atlas. Data for 10 noise-exposed nights and the same number of control nights were analyzed excluding the first-night data. The sleep parameters used were total sleep time (TST), each sleep stage in minutes, % of sleep stage against TST, sleep efficiency, sleep latency, REM latency, REM cycle, REM duration, waking from sleep, number of stage shifts and subjective sleep as judged by the OSA sleep inventory. The Mann-Whitney test was used for statistical analysis. TST, each sleep stage in minutes, % of sleep stage against TST, sleep efficiency, sleep latency, REM latency, REM cycle, REM duration, waking from sleep and the number of stage shifts of the exposure night did not significantly change compared to those of the control night. However, the sleep latency of the noise-exposed night increased significantly. Subjective sleep measured by five-factor scores and 8 items out of 29 constructing the five-factor scores of the OSA sleep inventory were decreased significantly by noise exposure, indicating deterioration of sleep quality.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1992

Validity of electrode placement at Fpz to detect alpha wave.

The possibility on placing electrodes at Fpz-A2 instead of C3-A2 was investigated to obtain a more stable configuration avoiding obstruction by the hair. Our original system of alpha wave detection by a microcomputer was used, and a total of 22 all-night hypnograms of five healthy young students was recorded. Pearson's moment correlation coefficients of alpha wave % between the two positions were 0.780-0.948. Except for one subject, alpha wave % taken at Fpz-A2 tended to be 3-5% lower than that at C3-A2. The above analysis indicates that using EEG electrode position of Fpz-A2 is valid and useful as a stable electrode configuration for a long-time monitoring.

Adult↗
PubMed1992

[The effect of noise on sleep--changes in hypnograms of subjects exposed to repeated truck-passing sound].

The effect of traffic noise on sleep was evaluated in an experimental room using repeated recorded truck-passing sounds. The peak sound level was 55, 60 or 65 dB (A) with frequencies of three times per hour. The background noise of the exposure night was Leq 42 dB (A) and that of the control night was Leq 35 dB (A). The subjects were five students 23 to 24 years old. The sleep stage of each epoch with a 20-second duration was judged visually based on the criteria of Rechtschaffen & Kales and the data of the second night of noise-exposure and the control night were used. The sleep parameters used were total sleep time (TST), each sleep stage, % of sleep stage against TST, sleep efficiencies, sleep latency, REM latency, REM cycle, REM duration, waking from sleep, number of stage shifts, and subjective sleep judged by the OSA sleep inventory. A paired t test was used for the statistical analysis. TST, REM stage in minutes, and % of REM stage against TST of the exposure night were significantly decreased compared with those of the control night. Other objective and subjective parameters showed no changes during noise exposure. Dividing the all-night into halves, the amount and % of each sleep stage were compared between the exposure and control night. There was no change of sleep stage in the former half, but the % and amount of REM sleep in the latter half were significantly decreased as a result of the noise exposure. The decreases of REM sleep and % REM against TST, especially in the latter half of all-night sleep, were caused by the intermittent truck-passing sounds 20 to 30 times per night.

Adult↗
PubMed1992

Effect of the continuity and sampling rate of polygraphy data on sleep stage by a computerized scoring system--a reliability study.

The percentage of each sleep stage determined by visual judgment was compared with computerized judgment using continuous and three intermittent sampling data. Comparison of stage agreements of four types of computerized judgments with visual judgment were also conducted. Hypnograms of six healthy young male students were recorded on each of five nights. Data of each subject were compiled individually, and the six data were analyzed. Agreement rate of the sleep stage by computerized judgment using continuous (method A), one-third (method B), one-ninth (method C), and one-fifteenth (method D) data with that of visual judgment were compared. The agreement rate of visual and computerized judgment using method A showed no difference from that between visual and computerized judgment using method B. There was a significant loss of agreement between visual and computerized judgment using method C or D compared with that between visual and computerized judgment using method A. Paired t-tests were conducted for each stage percentage against total sleep time of visual judgment and those of computerized judgments using method A, B, C, or D. There were no significant changes in any sleep stage percentages between visual judgment and computerized judgments using method A, B, C, or D. From sleep stage agreement and the degree of difference from visual judgment, the acceptable limitation of the sampling period was concluded to be one-third of continuous data.

Adult↗
PubMed1988

[2 surgically treated cases of adrenocortical carcinoma producing steroid hormones without endocrinological symptoms--case report and a review of cases in the Japanese literature].

We have experienced two male cases of an adrenocortical carcinoma that have produced steroid hormones without endocrinological symptoms. Both men were admitted to hospital because of an abdominal pain and left hypochondral tumors. In each case, an abdominal CT, an ultrasonogram and an angiogram demonstrated a left adrenal tumor, and levels of blood dehydroepiandrosterone sulfate, etiocholanolone, pregnenolone sulfate and urine 17 KS were elevated. The tumors were resected and the histology revealed that they were adrenocortical carcinomas. Postoperatively, the levels of their urine hormones returned to normal values, though in one man recurrence occurred a year later. Only 8 cases of an adrenocortical carcinoma that has produced steroids without specific endocrinological symptoms have been reported in Japan, and we also report on two cases herein.

17-Ketosteroids↗
PubMed1986

[von Recklinghausen's disease associated with pheochromocytoma--an autopsy case report and review of 24 cases in the Japanese literature].

A 56-year-old woman was admitted because of vomiting and right hypochondralgia. Since she was 25 years old, she had been sick with neurofibromatosis. Systemic neurofibromatosis with café-au-lait spots, blood hypertension and tenderness on the right hypochondrium were found. Ultrasonic examination revealed a right adrenal mass. Levels of serum catecholamines were elevated. She developed ileus and died of shock from the release of adrenal catecholamines. Postmortem examination showed right adrenal pheochromocytoma. The tumor measured 11.5 X 8 cm and weighed 25 gm. Von Recklinghausen's disease associated with pheochromocytoma is very rare, and only 24 cases have been reported in Japan. We present our case here with a review of the literature.

Adrenal Gland Neoplasms↗
PubMed1985

[Clinicopathological studies on disseminated carcinomatosis of the bone marrow occurring through metastasis of gastric carcinoma].

Five cases of gastric carcinoma (one woman) were investigated. The average age of the patients was 44 and the clinical manifestation were lumbago, melena and fatigue. Two cases were Borrmann III, and other were Borrmann IV, IIc and IIc advanced, respectively. Three were signet-ring cell carcinoma and the other two were moderately differentiated and well-differentiated adenocarcinoma, respectively. All patients showed leukoerythroblastosis. Bone marrow specimens revealed myelofibrosis in three cases, while adenocarcinoma cells were also found in three. MHA or DIC was found in three patients, all of whom died of bleeding tendency. Mean survival time was 2.6 months. Thus, bone marrow carcinomatosis proved to be very severe.

Adenocarcinoma↗
PubMed1985

[A case of primary adenosquamous carcinoma of the stomach preoperatively diagnosed by endoscopic biopsy].

A 53-year-old complained of upper abdominal pain. A diagnosis of Borrmann III type gastric cancer in the posterior part of the corpus region was made by X-ray and endoscopy, and primary adenosquamous carcinoma was preoperatively diagnosed by endoscopic biopsy. Subtotal gastrectomy was performed. The part of the adenocarcinoma adjacent to squamous-cell carcinoma was poorly differentiated. Adenosquamous carcinoma of the stomach is rare. Furthermore, preoperative diagnosis by endoscopic biopsy is extremely unusual, having been reported in 7 cases in Japan including ours. And in 5 cases out of 6, region of the adenocarcinoma was the poorly differentiated type.

Adenocarcinoma↗