PubMed Health⌕ Search

Biomedical subjects

Y Kitayama

Publications and source records attributed to Y Kitayama.

48 records · Page 3Linked to original sources
PubMed1994

Metastases from gastric adenocarcinoma presenting as multiple colonic polyps: report of a case.

A 53-year-old woman presented with symptoms of weight loss, diarrhea, and melena. A barium enema with endoscopy revealed multiple colonic polyps which were shown histologically to be metastatic deposits of poorly differentiated adenocarcinoma. The primary tumor, a poorly differentiated gastric adenocarcinoma, had been resected 11 years earlier. This appears to be only the second published report of polypoid colonic metastases from gastric adenocarcinoma.

Adenocarcinoma↗
PubMed1994

Alteration of immunoreactivity by hydrated autoclaving, microwave treatment, and simple heating of paraffin-embedded tissue sections.

The effects of treatment in a hydrated autoclave (121 degrees C, 2 atm for 20 min), microwave oven (in water), and simple heating (60 degrees C overnight in distilled water or 90 degrees C for 10 min in ZnSO4) on the stainability of 56 antigens by commercially available antibodies in formalin-fixed paraffin-embedded tissue sections were evaluated. The detectability of nuclear antigens, glycoprotein, lymphocytic surface markers, and chromogranin A was significantly and reproducibly improved by these treatments, whereas the detectability of viral antigens and peptide hormones was attenuated or unchanged. This enhancement includes not only the distinctiveness of the positive staining, but also the number of positive cells, as revealed by comparing serial sections. Among these four heating procedures, microwave heating and autoclaving were more effective than the others on p53, c-erbB-2, and CA125, whereas simple heating was best for smooth-muscle actin (HHF35 and CGA7). Generally the effects of the heating procedures for these antigens were consistent among the cases, but the effects on GFAP varied with the case. The alterations we observed could significantly influence the interpretation of immunohistochemical staining of currently popular tumor markers such as p53 in terms of their prevalence (28% vs 64% in gastric cancer; 36% vs 82% in metastatic liver cancer) and other diagnostically important markers.

Antigen-Antibody Reactions↗
PubMed1985

Malonyl-CoA: acetyl-CoA cycling. A new micromethod for determination of acyl-CoAs with malonate decarboxylase.

A new micromethod for determination of acetyl-CoA and malonyl-CoA using malonate decarboxylase is described. This enzyme catalyzes decarboxylation of malonate in a cyclic manner and produces acetate in proportion to the amount of a given acyl-CoA, such as acetyl-CoA, malonyl-CoA or propionyl-CoA. The acetate generated is converted to acetylphosphate by acetate kinase (EC 2.7.2.1) added at the same time and is determined spectrophotometrically as acetohydroxamate. The sensitivity of this method is high enough to detect 10(-12) mol of acetyl-CoA or malonyl-CoA. The simplicity of the method allows more than 30 samples to be analyzed at the same time without any prior extraction step. Although this method does not distinguish between acetyl-CoA and malonyl-CoA, malonyl-CoA alone can be measured by elimination of acetyl-CoA with citrate synthetase (EC 4.1.3.7).

Acetate Kinase↗
PubMed1985

Rudimentary polydactyly: report of five cases.

Rudimentary polydactyly was found in five patients. Surgical exploration of the papules revealed findings that have not been previously published. A cord-like structure arises from the bottom of the papule, with its proximal portion joining the neurovascular bundle of the digit. Histologic examination of the cord showed strong similarity to the neurovascular bundle of a finger. From these findings, we assume that rudimentary polydactyly may represent the amputation stump of pedunculated fingers.

Child↗
PubMed1985

High division of the median nerve: unusual anatomical variation.

An unusually high division of the median nerve in the forearm is reported. Recognition of this anatomical variation can help plastic surgeons make the proper diagnosis when encountering an incomprehensible clinical sign in the vicinity of the median nerve.

Child↗
PubMed1983

Congenital onychodysplasia. Report of 11 cases.

We have seen 11 cases of congenital onychodysplasia over the past six years. Associated anomalies were present in six patients, most of whom had an anomaly of the hand. Roentgenograms of the affected fingers showed hypoplasia, narrowing at the distal third of the distal phalanx, and bifurcation of the distal phalanx. The etiology of this condition is unknown, but clinical study suggested that ischemia of the finger at a certain period of embryonic life might play an important part in its pathogenesis.

Adult↗
PubMed1983

Patterns of arterial distribution in the duplicated thumb.

The arterial blood supply of the duplicated thumb was studied in 42 hands using the angiography technique. The developing factor of the duplicated thumb also may hinder the developing process of the limb artery, especially in the early stage when the median artery develops. In 73.8 percent of duplicated thumbs, two digital arteries were present, and 96.8 percent of them had one digital artery in each member. Simple ablation of the supernumerary digit leaves the thumb with a single end-arterial blood supply. The developmental mechanism of the duplicated thumb may depend not on duplication of the limb bud, but on splitting of the limb mesenchyme. The group of type VII of Wassel's classification was different from the other types in terms of origin of the digital artery distributing blood to the duplicated thumb.

Angiography↗
PubMed1981

Free vascularized fibular graft for replacement of the radius after excision of giant cell tumor: case report.

A case is reported in which a giant cell tumor of the distal end of the radius was treated by massive resection and reconstruction with a free vascularized bone graft taken from the fibula. The postoperative course was uneventful. Angiograms made eight weeks after surgery showed patent anastomoses. One year after surgery there was no evidence of recurrence of the tumor, and roentgenograms showed no degenerative changes and bony union with hypertrophy at the junction of the radius and the graft. An excellent clinical result was obtained, and the patient was able to return to his original occupation as an illustrator.

Bone Neoplasms↗
PubMedDate not supplied

Bilateral diaphragmatic hernia followed by fetal ultrasonography. A report of two cases.

Two cases of bilateral congenital diaphragmatic hernia (CDH) followed by fetal ultrasonography were described. Although many cases of CDH are diagnosed by fetal ultrasonography, it is difficult to diagnose bilateral CDH in utero, which is a relatively rare and fatal condition. Two fetuses were diagnosed as having left CDH associated with severe anomalies. However, a retrospective review of fetal ultrasonography indicated elevation of the liver in the right posterior chest. Both patients died shortly after surgical repair for left CDH despite the use of extracorporeal membrane oxygenation. Diagnosis of bilateral CDH by fetal ultrasonography and the evaluation of its prognosis were discussed.

Fatal Outcome↗
PubMedDate not supplied

Effects of sevoflurane anaesthesia on renal function.

The effects of sevoflurane on renal function were investigated in 34 patients anaesthetized with sevoflurane. Based on preoperative serum creatinine levels, patients were classified into three groups: Group 1 (n = 25) had normal renal function (serum creatinine < 1.0 mg/dl); Group 2 (n = 5) had slight renal dysfunction (1.0 < or = serum creatinine < 1.5 mg/dl); Group 3 (n = 4) had moderate renal dysfunction (serum creatinine > or = 1.5 mg/dl]. Serum creatinine, blood urea nitrogen and urine volume were measured preoperatively, and at Days 0, 1, 2, 7 and 28 after operation. Serum creatinine and blood urea nitrogen showed no significant postoperative differences (P < 0.05) in each group, whereas urine volume showed a significant increase until Day 2, with no further changes thereafter. Our results suggest that sevoflurane anaesthesia causes no significant renal damage in patients with normal and insufficient renal function under normal-duration anaesthesia within 3-4 h.

Adult↗