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Biomedical subjects

Y Kitazoe

Publications and source records attributed to Y Kitazoe.

8 recordsLinked to original sources

Development of a diagnostic and therapeutic simulation system based on patient data and specialist's knowledge. I. Simulation of diagnostic process.

A new simulation system of diagnostic and therapeutic processes is developed. The aim is to train medical students for the practical use of their knowledge, utilizing patient data in a total hospital information system. The knowledge in the system is presented by the specialists for every case. In medical school there are many specialists in various fields. With their cooperation the system can grow up to a comprehensive CAI system for clinical education. The system is designed to work on the mainframe for easiness of development, maintenance and extensions of the system. The present framework has been applied to the simulation of diagnostic process. The usefulness of the present system has been confirmed by specialists and students.

Computer-Assisted Instruction

New control chart for multivariate data with missing values.

A new multivariate statistical quality control method has been developed. It is an extension of the method developed by Kume, which is able to find abnormal values in multivariate biochemical data of a clinical laboratory. The present method makes use of the difference between two sets of data measured from the samples of the same patient obtained on different days. The Mahalanobis' distance between two samples can be calculated from the difference of their observations. If the Mahalanobis' distance of the two data is larger than the critical value decided in advance, the reliability of the measurement is doubtful. The characteristic of the present method is that it can apply to data with missing values by estimating them from measured data. Some numerical examples are shown to demonstrate the availability of the method.

Algorithms

Use of a computer in analysis of heart rate and blood pressure response to the Valsalva maneuver.

The relationship between systolic blood pressure (SBP) and R-R interval (RR) in phase II of the Valsalva maneuver was analyzed with the use of a nonlinear relation. The nonlinear relation introduced here includes time derivatives of SBP and RR, and is a natural extension from the linear one which defines the linear baroreflex sensitivity index (BRSI). The model equations of SBP and RR derived from the nonlinear relation predicted well the observed changes of SBP and RR in 11 normotensive subjects and 16 hypertensive patients. Two of the parameters of the relation were related to the activity of the compensatory mechanism, and discriminated well the hypertensives from the normotensives. For this analysis an interactive system of regression analysis has been developed to reduce the difficulties in the case of nonlinear regression curve fitting. The regression curves can be monitored on a graphic terminal during every regression step. The values of nonlinear parameters can be obtained easily and systematically with use of the system.

Adult

Analysis of the online order entry process in an integrated hospital information system.

In Kochi Medical School Hospital, many online order systems have been developed as a part of the integrated hospital information system named IMIS KOCHI. The prescription, laboratory and radiology orders are used frequently and entered into the system by physicians. The distribution of entry duration of these orders by physicians was analyzed and it was found that the order entry is a completely random event and the entry process consists of the two Poisson processes; the quick process and the slow process. The two Poisson processes were observed even in the do-prescription order without correction by trained physicians. It is speculated that the quick process depends on availability in the order entry system and the slow process depends on peculiarities in clinics, and the mental condition of physicians.

Drug Prescriptions

Efficacy of a computerized system applied to central operating theatre for medical records collection.

A computer system operation is introduced, which has been in use since October 1981 at Kochi medical school as one of the integral sub-systems of the total hospital information system called IMIS. The system was designed from the beginning with the main purposes of obtaining better management of operations, and detailed medical records are included for before, during and after operations. It is shown that almost all operations except emergencies were managed using the computer system rather than the paper system. After presenting some of the results of the accumulated records we will discuss the reason for this high frequency of use of the computer system.

Computer Systems

Online support functions of prescription order system and prescription audit in an integrated hospital information system.

The role of the online prescription support functions of a prescription order entry system was analysed and the results of the prescription audit by pharmacists were examined. In the Kochi Medical School Hospital, an online prescription order system has been developed as part of an integrated hospital information system named IMIS (the Integrated Medical Information System), in which all the physicians enter their prescription orders into online display terminals. The prescription order entry system is provided with prescription support functions, which check the entered prescription data, issue warnings, and offer information about drugs or patients. The prescription order system reduces the incidence of simple prescription mistakes and greatly decreases the cases of inquiries by pharmacists. However, results of the analysis show that such functions as warnings of double order and repeated prescription of a drug do not work as well as expected. The system would thus require some kind of intelligence like that of the auditing pharmacists or that of the physicians with accurate knowledge of clinical pharmacology.

Drug Prescriptions