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Biomedical subjects

Y Kornizky

Publications and source records attributed to Y Kornizky.

3 recordsLinked to original sources

The value of stress thallium-201 single photon emission CT imaging as a predictor of outcome and long-term prognosis after CABG.

This study examined the capability of rest-redistribution 201Tl single photon emission CT imaging (TSPECT) done shortly after coronary artery bypass grafting (CABG) to predict outcome and long- term prognosis. Results of TSPECT at 5.5+/-0.7 (range 4 - 8) months postoperatively were correlated during a 4-year follow-up period wit mortality, major surgical and nonsurgical cardiac events and cardiac event-free survival in 170 patients who underwent CABG. Ten (5.8%) patients died during follow-up: 4 had a documented cardiac death (all of them with large or moderate reversible filling defects). In the survivors, there were 10 nonfatal myocardial infarctions and 11 revascularization interventions. Patients who eventually required and underwent revascularization procedures demonstrated large or moderate reversible filing defects, in contrast with those who had no need for an additional procedure (15.7% versus 2.5%, p < 0.001). Postoperative TSPECT carried out soon after CABG had definite prognostic value and should be performed routinely to help decide treatment protocol.

Adult↗

Dysphagia with multiple autoimmune disease.

Myasthenia gravis (MG) and polymyositis (PM) are organ-specific autoimmune diseases. Occasional reports describe patients with clinical and pathologic features of both. Achalasia is idiopathic in nature, but autoimmune and inflammatory mechanisms have been proposed for this disorder as well. We describe a patient with dysphagia who was diagnosed at different points in time with all these three rare conditions. Despite at least putatively having immune mechanisms in common, an association between the three has not been previously described.

Aged↗

Specific IgE antibodies to aeroallergens and food among Israelis.

BACKGROUND: There are no data about specific IgE antibodies to food and aeroallergens in the Israeli population. OBJECTIVE: We sought to determine the relationship between selected demographic parameters and rate of sensitivity to various allergens throughout all ages. METHODS: Analysis was carried out on 776 positive specific IgE from 655 patients (347 to food, 429 to aeroallergens, and 121 to both). The studied parameters were age and gender. RESULTS: Age-related analysis showed the highest positivity to food (eggs, legumes, and milk) and the lowest to pollens during infancy. High sensitivity to house mites prevailed at all ages. Sensitivity to pollens and epidermals increased with age while sensitivity to eggs, legumes, and milk decreased. Above the age of 30 years, the rate of sensitivity to all tested aeroallergens and food was similar and close to the average value. Our data showed a significant cross-sensitivity between various foods and aeroallergens and also confirmed cross-sensitivity results reported earlier. CONCLUSIONS: (1) Age is a dominant factor affecting type I hypersensitivity. House mite is the most common allergen throughout life. (2) The age distribution and nature of sensitivity to allergens in Israel has some similarities to Spain but differ from other countries. (3) Cross-sensitivity between food and aeroallergens was found.

Adolescent↗