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Biomedical subjects

Y Kozono

Publications and source records attributed to Y Kozono.

35 records · Page 2Linked to original sources
PubMed1994

Combined testosterone treatment in pubertal and adult periods induces male-specific acetohexamide reductase activity in liver microsomes of female rats.

The influence of testosterone treatment on acetohexamide reductase activities in liver microsomes and cytosol of female rats was examined. Acetohexamide reductase activity in liver microsomes was much lower in female rats than in male rats. Combined testosterone treatment in pubertal and adult periods induced male-specific acetohexamide reductase activity in liver microsomes of female rats. However, testosterone treatment only during puberty or during adulthood was without effect. Testosterone secreted from the testes during puberty appeared to have a significant effect similar to neonatal imprinting in the induction of acetohexamide reductase activity in liver microsomes of female rats. The combined testosterone treatment, or testosterone treatment only during puberty or during adulthood had no effect on acetohexamide reductase activity in liver cytosol of female rats.

Aging↗
PubMed1991

YACs and the C. elegans genome.

During the past decade, it has become apparent that it is within our grasp to understand fully the development and functioning of complex organisms. It is widely accepted that this undertaking must include the elucidation of the genetic blueprint - the genome sequence - of a number of model organisms. As a prelude to the determination of these sequences, clone-based physical maps of the genomes of a number of multicellular animals and plants are being constructed. Yeast artificial chromosome (YAC) vectors, by virtue of their relatively unbiased cloning capabilities and capacity to carry large inserts, have come to play a central role in the construction of these maps. The application of YACs to the physical map of the Caenorhabditis elegans genome has enabled cosmid clone 'islands' to be linked together in an efficient manner. The long-range continuity has improved the linkage between the genetic and physical maps, greatly increasing its utility. Since the genome can be represented by a relatively small number of YACs, it has been possible to make replica filters of genomically ordered YACs available to the community at large.

Animals↗
PubMed1989

Analysis of abutment tooth movement utilizing mandibular kinesiography (MKG). Part 2. Effects of clasp design in unilateral free-end denture.

The three-dimensional dynamic movement of the abutment tooth was successfully analyzed on a simulation model utilizing the mandibular kinesiography. When the unilateral free-end denture retained by the RPA, RPI or Aker's clasp was subjected to various directions of loads, the abutment tooth was inclined mainly by the sliding displacement of the denture over the alveolar ridge and the lever action around the denture. The Aker's clasp assembly induced the largest tooth movement. The RPA clasp generally exhibited similar tendencies to the Aker's clasp, showing a larger tooth inclination in the disto-buccal direction. The RPI clasp seemed to be preferable for protecting the periodontal tissues from damage associated with unfavorable tooth movements since it induced less distal tooth inclination.

Dental Abutments↗
PubMed1989

[Changes in retention strength of luting cements by repeated loading].

The retention of crowns cemented on abutment tooth model was examined for three types of luting cements when compressive loads of 2.5 to 10.0 kg were repeatedly applied to the occlusal plane. The chamfer type Ni-Cr alloy crown and abutment tooth model were prepared, and their surfaces to be cemented were sandblasted with glass beads. Loads were applied 7,200 times a day for 1, 3, or 7-day period after cementing. The polycarboxylate and zinc phosphate cements showed higher crown retentions than glass ionomer cements. Although retention strength of glass ionomer cements was significantly increased by storing the cemented specimen in water for 7 days, repeated loading tended to decrease retention. In polycarboxylate cements and one brand of zinc phosphate cement employed, retention strengths were decreased when stored in water over 3 days. However, their highest levels were maintained or even positively impacted by repeated loading for 7 days.

Crowns↗
PubMed1988

Reproducibility of the vertical dimension of occlusion with an improved measuring gauge.

An improved gauge using an eyeglass frame, the TOM gauge, was devised. The reproducibility of the record of vertical dimension with this gauge was evaluated through repeated measurements on subjects having a definite centric stop with the natural dentition. Because of the stabilization provided by the frame and the reference point on the apex nasi, the TOM gauge showed excellent reproducibility of the record compared with the conventional gauges. The TOM gauge can be expected to significantly reduce the risk of errors in measuring the vertical dimension of occlusion especially in complete denture fabrication.

Chin↗
PubMed1982

Dissolution of amalgam in saline solution.

This experiment was designed to investigate the in vitro corrosion of several modern dental amalgams in saline solution over a six-month period by measuring changes in the soluble corrosion products. Based on the change of the electrical conductivity of the solution, the dissolution rate seemed to decrease gradually for the first three to four months. Then a rapid increase was observed, indicating a reactivated corrosion process. Larger dissolutions of copper and mercury were observed, especially for the high copper alloys, in these later stages. Zinc and indium, if present, were preferentially released at the earlier stages. Silver and tin could not be detected. Evidence exists that the corrosion of tin results in insoluble deposits of corrosion products.

Copper↗