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Biomedical subjects

Y Kuru

Publications and source records attributed to Y Kuru.

16 recordsLinked to original sources

Pure memory loss with hippocampal lesions: a pneumoencephalographic study.

A case of pure memory loss occurred suddenly following inhalation anesthesia. Examination seven years after the onset of amnesia disclosed a profound and selective impairment of recent memory without concomitant deterioration of other higher functions or evidence of other neurologic abnormalities. Pneumoencephalotomography focused on the temporal horns showed severe atrophic changes confined to both hippocampi. This finding provides a radiologic counterpart of previously reported surgical and pathological observations of bilateral hippocampal lesions in cases with relatively pure loss of memory.

Amnesia

Basiparallel cut by pneumoencephalotomography and cerebellar atrophy.

The basiparallel cut is a nearly horizontal slice of the posterior fossa used in air study and the structures are observed on a plane parallel to the clivus. Total shrinkage of the cerebellum, with or without fourth ventricle dilatation, was found in cases of olivopontocerebellar atrophy, some intoxications, and a few senile subjects. Some atrophy of paleocerebellar portions was seen in Holmes-type degeneration. Another pattern was symmetric shrinkage of neocerebellar lobules and relatively specific for the cases of 'multiple system atrophy' such as progressive supranuclear palsy, striatonigral degeneration, Marie's ataxia, etc. Loss of the superior cerebellar peduncle was clearly demonstrated in this view.

Adult

Ammon's horn sclerosis on pneumoencephalotomography.

Fourteen cases with psychomotor seizure were examined by pneumoencephalotomographic technique. In all cases uni- or bilateral changes of the inferior horn were found: diverticular dilatation of subiculum, lowering and irregularity of the floor, reduction of width, and deformation of digitation. These findings correlated well with the autopsy reports. In most cases, EEG findings also correlated.

Adult

Computed tomography of brains of epileptic children.

1) Most of the intractable epileptic children showed abnormal EEG and abnormal CT findings. 2) The abnormal side of CT findings of focal epilepsy corresponded with the abnormal side of clinical manifestations and EEG findings. 3) CT findings of the brains of patients with infantile spasms exhibited cerebral cortical atrophy. 4) CT findings of the brains of the other epileptic types were not related to clinical manifestations or EEG findings.

Brain