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Biomedical subjects

Y Lynfield

Publications and source records attributed to Y Lynfield.

15 recordsLinked to original sources
PubMed1992

Scurvy.

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Ascorbic Acid↗
PubMed1990

Dialysis acne.

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Acne Vulgaris↗
PubMed1989

Sulconazole nitrate 1% cream in the treatment of chronic moccasin-type tinea pedis caused by Trichophyton rubrum.

Sulconazole nitrate 1% cream applied twice daily was compared with its vehicle in the treatment of 229 patients with chronic moccasin-type tinea pedis confirmed by positive results of a potassium hydroxide preparation. At admission in this randomized, double-blind, parallel multicenter trial, 131 patients had positive dermatophyte cultures; Trichophyton rubrum was identified in 121 (92%). After 4 weeks of treatment, patients were examined and, if necessary, were treated for an additional 2 weeks. Sulconazole cream was significantly more effective than the vehicle in the treatment of chronic T. rubrum tinea pedis; 57% of patients were cured by sulconazole, compared with 13% cured with the vehicle. Relapse rates, assessed 2 weeks after the end of treatment, were significantly lower in patients treated with sulconazole than in those receiving vehicle (27% vs 71%). The 103 patients with moccasin-type tinea pedis whose cultures were not positive for T. rubrum achieved similar results.

Adolescent↗
PubMed1979

Insulin allergy. Report of a case with delayed local reaction.

A diabetic patient had delayed local cutaneous allergic reactions to insulin. We describe his lesion, biopsy findings, and treatment. Allergic reactions to insulin may be immediate local or systemic, which are lgE-mediated. Recommended management of local reactions is to use a single-peak pork insulin of the insulin zinc suspension series. Progressive immediate local reactions may herald the onset of systemic reactions. Hospitalization and desensitization to insulin may be required for systemic allergic reactions to insulin.

Aged↗
PubMed1976

Psoriasis: topical corticosteroid therapy.

Fifty-nine patients with bilateral psoriatic lesions were subjects in a double-blind paired comparison of halcinonide cream and fluocinonide cream. They applied the corticosteroid creams twice a day for 14 days without occlusive dressings. Objective and subjective assessment of response to therapy was made four or five days, one week, and two weeks after starting treatment. The results were analyzed by statistical methods. At the second visit (day 4 or 5), there was little difference between the two compounds, but at visits three and four, reduction of inflammation was significantly better with halcinonide than with fluocinonide.

Adult↗