[Bilharzial invasion. Diagnosis and early treatment].
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Adult↗
Biomedical subjects
Y Mafart
Publications and source records attributed to Y Mafart.
[Recent aspects of tuberculous peritonitis (22 cases in the adult) (author's transl)].
The authors show in this work the principal features of 22 tuberculous peritonitis cases seen between 1967 and 1977 affecting 17 Black Africans, 2 West Indians and 3 French (metropolitan) Caucasians cirrhotic or alcoholic. The 9 ascitic forms are not in the majority but it is worthwhile to consider a laparoscopy with peritoneal and/or hépatic biopsy where there is abdominal pain or unexplained fever. In most cases there exists one or several other tuberculous sites particularly pleural, pulmonary, hepatic, or in the cases of the Africans mediastinal lymphadénopathy. The means of diagnosis are commented upon with stress on the importance of peritoneoscopy and biopsies. The prognosis is good provided that antituberculous treatment is employed over a period of one year, with or without the temporary conjunction of corticosteroids.
Adult↗
[Two cases of tuberculosis of the skull cap (author's transl)].
The authors report two cases of tuberculosis of the skull cap. The first in a Black African with heterozygous sickle cell disease also presenting with: tuberculosis of the cervical lymph nodes, subcutaneous frontal tumefactions bacteriologically confirmed to be of tuberculous origin, multiple lacunae of the vault from the same origin; the second case is an Asian woman having a multifocal tuberculous osteitis involving the skull, spine, pelvis and probably the same affection in the spleen. These cases are a reminder that the principal features of tuberculosis of the skull vault are very often associated with other tuberculous lesions, and to the problems of diagnosis it entails; the existence of a subcutaneous tumefaction of the vault or of any accessible site one can aspirate and/or perform biopsy constitutes a diagnostic aid.
Adult↗
[Calcified and suppurated epidermoid cyst of the spleen (author's transl)].
Reporting a case of epidermoid cyst of the spleen revealed on suppuration brings the authors to review the classification of epidermoid cyst. These are benign tumors in the main present clinically with left hypochondrium pain and the possibility to palpate a splenomegaly or mass in this hypochondrium. The diagnostic approach includes diverse investigations, in particular a series of radiological examinations; surgical intervention will confirm and avoid complications.
Adolescent↗
[One hundred and twenty-three cases of sickle-cell trait (author's transl)].
One hundred and twenty-three cases of sickle-cell trait (122 negro immigrants) are studied in a department of internal medicine. The frequencies of G6PD deficiency, anemia, splenomegaly and tuberculosis are neighbouring at the negro without hemoglobinopathy. The relationship between the sickle-cell trait and the reason of admission of the final diagnosis il likely in 2,4 % of the cases, doubtfully in 15,4 %, null in the other cases. The occasional (hemolytic, thrombotic, painful, visceral, osseous) manifestations of the sickle-cell trait (apart from the constant hyposthenuria) and their mechanism are summarized and discussed.
Africa↗
[Osseous manifestations and hemoglobinopathies C (author's transl)].
The authors report two cases of hemoglobin C trait and hemoglobin C disease with bone tuberculosis and, in the first case, bone infarction of one condyle two years after the tuberculosis of the other knee. This suggests the possibility of osseous manifestations in the course of hemoglobin C trait or hemoglobin C disease apart from hemoglobin SC disease.
Adult↗
[Osseous manifestations of treponematoses : six cases in immigrated black African (author's transl)].
The authors report the cases of six immigrated Black Africans with clinical and radiological (4 cases with condensing osteitis ; 2 cases with condensing forms and multiple lacunae) bone manifestations ; these manifestations, the serological tests and the osseous biopsy (three cases out of four) are consistent with the diagnosis of bone syphilis. These facts are discussed and ascribed to tertiary syphilis rather than to congenital or secondary syphilis, to yaws or endemic syphilis.
Adult↗
[152 cases of tuberculosis in African Negro immigrants in a Parisian service of internal medicine (author's transl)].
This study of 152 cases of tuberculosis in African Negro immigrants seen between 1972 and 1976 showed the predominance of especially pulmonary respiratory lesions and/or hilar ganglio-mediastinal lesions. The other lesions are frequent, i.e. the lesions of lymph nodes, bones, peritoneum, liver, pericardium ; the multiple lesions are likewise frequent. Smears and culture of sputum and/or biopsy of organs or tissues such as pleura, lymph node, liver and peritoneum are the diagnostic procedures. In spite of frequent resistance, treatment with isoniazid, rifampicin and ethambutol gave good results in high risk subjects, who are almost always allergic on arrival in France.
Adult↗
[Oltipraz in brief treatment of S. haematobium schistosomiasis. 3 doses per day or single dose].
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Drug Administration Schedule↗
[Diagnostic value of parasitologic examinations and of indirect immunofluorescence test in S. haematobium schistosomiasis (author's transl)].
A study has been carried out in 690 patients admitted in a Paris hospital and from Mali, Senegal and Mauretania origin, in order to compare the three available techniques for the diagnosis of infection with S. haematobium: urine centrifugation deposit control, biopsy of rectal mucosa and indirect immunofluorescence test. The prognostic value of each of these three techniques has been reevaluated. (Formula: see text), Living eggs have been detected in 55 p. 100 of the patients by direct examinations and a prevalence of 75 p. 100 has been computaned for S. haematobium.
Fluorescent Antibody Technique↗
[Oltipraz as brief treatment of schistosomiasis (comparison with niridazole) (author's transl)].
161 patients affected by schistosomiasis due in most cases to S. haematobium, and less frequently to S. mansoni, received one day treatment with 4,5 g a day of oltipraz in a first group and, later on, 3 g a day in another group. A control after one year was possible for patients having received 4,5 g one day dosis. Urin control, rectal mucosa biopsy (R.M.B.) and indirect immunofluorescence test (I.I.F.) were performed in patients who did not return to infested areas during that period of time; in almost all cases, the urin control was negative; in 52 p. 100 of the cases the R.M.B. shown no live egg and I.I.F. test was significantly decreased with individual variations. -- These results are compared to those of a previous and similar study on the effects of niridazole. -- Side-effects, mostly digestive or nervous, are frequent with a 4,5 g dose and less frequent with 3 g. They rarely compel to discard the treatment and they never persist after the morning following the treatment is stopped. There is no electrocardiographic change. -- Doses below 3 g in one-day intake are presently studied in order to fix the minimal acting dosis.
Adolescent↗
[A new case of Plasmodium falciparum malaria resistance to chloroquine in Africa (Rwanda) (author's transl)].
Report of a case of P. falciparum malaria observed in Rwanda. Relapse and positive blood thick smear has been observed 8 days after the beginning of the treatment of the previous fit of fever by chloroquine. Authors recall the resistance criteria fixed by O.M.S. for antimalarial drugs and question wether drug-resistant malaria is not spreading in East-Africa, considering some similar cases reported in the region.
Chloroquine↗
[Pulmonary complications of drepanocytemia: recent advances (author's transl)].
Pulmonary complications are non very frequent in drepanocytemia (3 to 7 p. 100) but they are often severe and sometimes dramatic. They happen in the homozygotic forms or in the double heterozygotic ones (SC and Sbeta Tahal). Infections, most often due to pneumococcus, are specially frequent in children, though infractions are generally observed in youth and grown-ups. All these patients suffer of an impairement of their respiratory function and of their immunological capacity.
Acute Disease↗