Studies on the metabolism of hexosamine. A kinase activity for D-glucosamine without inhibition by glucose in rat liver and its possible identity with glucokinase.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to Y Miyatake.
Explore the source record for details and available documents.
D-Glucosamine was found to be phosphorylated by a rat liver extract in the presence of a high concentration of glucose, which was formerly believed to be a strong competitive inhibitor of this reaction. Results suggested that glucosamine may be phosphorylated by high Km hexokinase, i.e. glucokinase [EC 2.7.1.2]. The enzyme involved was separated from specific N-acetyl-D-glucosamine kinase [EC 2.7.1.59]. The phosphorylation was not inhibited by a physiological level of glucose or glucose 6-phosphate, which strongly inhibited low Km hexokinase. The apparent Km of glucokinase for glucosamine was estimated as 8 mM, which is ten times that of low Km hexokinase.
We present a rare case of benign intraosseous desmoplastic fibroma, occurring in the tibial bone of a 48-year-old woman. The plain film features consist of a lytic, expansile lesion, in the metaphysis and epiphysis of the bone. We present a case involving the long bone in which the correct diagnosis was suggested by CT and MRI. The appearance of the lesion on CT and MR is described.
UNLABELLED: The purpose of this descriptive study was to identify the decision-making style among the dialysis patients. Subjects were a Convenience sample of hemodialysis patients who agreed to participate this study. The data was collected through semi-structured interviews. The interviews were recorded on the tape and transcribed. Decision-making episodes were picked and interpreted by searchers. Data was analyzed based on the Inductive Theory Approach. RESULT: Subject were 21 patients from 4 hospitals. The mean age was 51.1 and the mean duration after they started the hemodialysis was 9.1 years. The 16 decision-making styles were identified: accept, unvacillate, resignation, compromise, perseverance, challenge, self-activation, groupie, crisis-avoidance, withdrawal, prudent, reserve, escape, refusal, dogmatic, and entrust. These 16 decision-making styles were characterized by the reality oriented perception, the constructive regimes, the higher quality of social support. On the other hand, the passive decision-making styles were characterized by the distorted perception, the passive regimes, and the poor social support. DISCUSSION: The reality orientation, energy, openness, values system were discussed as key factors which determined the decision-making style among hemodialysis patients. The nursing approach supporting the patients to make their decision were discussed.