PubMed Health⌕ Search

Biomedical subjects

Y Moride

Publications and source records attributed to Y Moride.

20 records · Page 2Linked to original sources

Interrater reliability of the modified Jadad quality scale for systematic reviews of Alzheimer's disease drug trials.

Drug therapies for Alzheimer's disease (AD) have been evaluated in clinical trials over the past 2 decades. Systematic reviews of AD drug trials can shed more light on the efficacy of pharmaceutical interventions. The modified Jadad scale can be used to assess the quality of trial reports that are candidates for inclusion in these systematic reviews. The interrater reliability of the modified Jadad scale was examined during such a review. Three blinded reviewers rated the quality of 42 AD drug trial reports: the intraclass correlation coefficient was 0.90. The modified Jadad scale appears to be a useful tool for AD research because of the very good interrater reliability. Also, it is composed of items that are well suited to the specific disease characteristics of AD. Further research should focus on the validity of this instrument.

Alzheimer Disease↗

Monitoring of drug utilization in public health surveillance activities: a conceptual framework.

The surveillance of individual and aggregate patterns of prescribed medication can potentially provide some very useful information to those involved in public health. At present however, this activity has attracted relatively little attention in Canada. This article will introduce a conceptual framework with which to examine the possibilities of prescription drug monitoring as a tool for public health surveillance. The sources of data available to undertake this activity as well as their limitations, will be presented along with some recent concrete applications.

Databases, Factual↗