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Y Navelet

Publications and source records attributed to Y Navelet.

At least 37 records · Page 2Linked to original sources

[Disorders in sleep organization in pediatric diseases].

Interactions between sleep and general pathology in pediatrics are numerous and little known. Sleep organization evolves with age and stages of development. The most important physiological sleep changes occur during the first year of life. The main symptom of sleep disorders is excessive daytime sleepiness associated with dyssomnia, behavioral and learning disorders. Sleep disorders in childhood are often difficult to evidence, sleep investigations being still heavy and expensive.

Age Factors↗

[Serious acute hepatocellular insufficiency in children: EEG prognostic features].

Fulminant Hepatic Failure (FHF) in children leads to 60 to 90% of mortality without age influence, depending on the studies. Twenty-two children with this disease had daily EEG, 15 died, seven survived. The neurological electroclinical study evidenced a stereotyped evolution of the EEG anomalies which were not age-related, but correlated to clinical stages of coma and to severe coagulation disorders; 5/22 children with clinical and/or EEG convulsive disorders died. One child exhibited triphasic slow waves and died from paracetamol intoxication. A prospective study of a larger population could help to recognize factors of decision for hepatic transplantation.

Adolescent↗

[The child insomniac].

The most frequent of sleep disorders in children are repeated and prolonged wakeful periods. One month old infants are normally awake during one-third of the nocturnal sleeping time. Gradually, sleep moves into night and wakefulness into daytime. At 3 years, 25 to 38% of children wake up during the night, but after 5 years this proportion becomes negligible. Apart from acute or chronic diseases which may produce sleep disorders, most of these are due to environmental factors. Two syndrome are worthy of special mention: deficiency of slow wave and deep sleep in psychosocial dwarfism, and insomnia due to intolerance to cow's milk. Treatment of insomniac children rests on behavioural techniques: parents must be helped to understand and observe the sleep-wake rhythm of their children and teach them to acquire regular sleeping habits.

Age Factors↗

Short- and long-term prognostic value of the electroencephalogram in children with severe head injury.

To determine the prognostic value of the EEG in severely head-injured children, 24 patients were studied for 8-36 months. During coma, 4 EEG patterns were found: borderline, sleep-like, changeable and slow monotonous (SM). For the short-term prognosis, we conclude that the SM pattern (12/24 patients) indicates a bad prognosis because it was associated with a longer coma and awakening period than that of other EEG patterns and because it was observed in the 3 patients who died from brain injury. In contrast, we describe a 'prewake' pattern (11/22 survivors) which, when it occurs, always announces the onset of a complete awakening. For the long-term prognosis, only 50% of the survivors who had an SM pattern during coma have as good an intellectual and motor outcome as the survivors who displayed other EEG patterns. No other EEG features recorded during coma have short- or long-term prognostic significance.

Child↗

Seizures presenting as apnoea.

Between the ages of 3 and 6 months a baby boy presented with repeated, non-specific episodes of cyanosis, apnoea, bradycardia, and abnormal movements of the limbs. The episodes were severe and required resuscitation and several admissions to hospital. Initial investigations showed only signs of oesophagitis. Despite treatment of the oesophagitis the symptoms recurred, and electroencephalography and polygraphy eventually showed evidence of minor seizures. Severe epilepsy with tonic-clonic seizures developed when he was 6 months old.

Apnea↗

[Prognostic factors in cerebral hypoxic-ischemias in infants less than a year old].

In order to establish criteria for early cerebral prognosis after acute cerebral hypoxic ischemic insult, we studied 31 cases of patients presenting, during their first year of life, cardio-respiratory arrests due to SIDS (21 cases), anesthesia (4 cases), other causes (6 cases). A favourable evolution was observed in 5 cases where coma lasted less than 8 hours. Conversely unfavorable evolution was seen in the 26 patients (21 deaths, 5 sequellae) where coma lasted more than 8 hours. Among 12 patients of this group surviving after the 4th day, 9 expressed seizures or status epilepticus. The poor evolution was correlated with hyperproteinorachia during the first 24 hours and with cortico-subcortical hypodensity on CT scan. Early EEG and transfontanellar echography seemed less useful to establish a prognosis, specifically to discriminate children surviving with and without sequelae.

Brain Ischemia↗

[A spectacular and benign syndrome of neonatal convulsions: deep sleep myoclonus].

Four case reports concerning neonates presenting, without any predisposing factors, severe and lasting myoclonus, occurring exclusively during sleep. These began between 1 and 4 days of age and stopped between 3 weeks and 5 months. Electro-encephalogram was normal, even during episodes of clonus which occurred during deep sleep. A predisposing genetic factor is likely. A better knowledge of this syndrome should avoid hospitalizations and misuse of anticonvulsive treatments.

Electroencephalography↗

Nocturnal sleep organization in infants "at risk" for sudden infant death syndrome.

Nocturnal sleep organization was compared in normal infants and those "at risk" for sudden infant death syndrome (SIDS) (siblings and near-miss infants). Before 12 weeks of age, sleep modifications were observed in "at risk" infants. During their sleep they had a smaller percentage of intervening wakefulness with a higher amount of active sleep. Quiet and active sleep episodes had longer durations resulting in a longer sleep cycle. After 12 weeks, sleep organization tended to normalize. This fact is discussed as a possible factor for a SIDS event: a higher arousal threshold could play a critical role if homeostasy is disturbed during sleep, mainly at an age when the homeostatic control is not fully established.

Age Factors↗

Nocturnal sleep organization during the first months of life.

42 healthy infants (18 boys and 24 girls) aged 4-30 weeks had polygraphic whole night recordings. Four sleep stages were identified, using standard sleep scoring parameters: intervening wakefulness (W), quiet sleep (QS), active sleep (AS) and transitional sleep (TS). Our results show, first, an important decrease of the intervening wakefulness between 4-5 weeks and 6-7 weeks, then a modification of the distribution of this intervening wakefulness after 21-22 weeks. QS increases significantly from 4-5 weeks to 27-30 weeks with a linear distribution throughout the night. The QS modifications seem related to the appearance of sleep spindles between 6 and 11 weeks. Intervening wakefulness and quiet sleep changes appear simultaneously with the emergence of the circadian rhythm. Active sleep and transitional sleep remain stable from 4-5 weeks to 30 weeks. Furthermore, no change in the internal organization is observed for active sleep during this period.

Age Factors↗

Fifth day fits.

Explore the source record for details and available documents.

Humans↗

[EEG appearance during waking and falling asleep in children aged 1-4 years (without serious pathology)(author's transl)].

The authors have studied the EEG characteristics of 188 children aged 1-4, without serious pathology, during waking and falling asleep spontaneously in the afternoon. The children were divided into 3 groups: aged 12-23 months, 24-35 months and 36-47 months. On falling asleep the EEG appearances varied, but hypersynchrony was most marked in the youngest children and in the older group theta activity was commonest. Only 3 of the 188 children had runs of paroxysmal activity on falling asleep. The waking study again showed appearances governed by the patients' age with respect to 7 c/sec activity on provoked waking, but the appearances were more diverse on spontaneous waking and anterior theta activity only occurred in the oldest children. In general, a relation appeared to exist between the EEG appearance on falling asleep and on waking, in the respect that children falling asleep without hypersynchrony never wake up with it.

Age Factors↗

[What's new about the fifth day seizures syndrome? (author's transl)].

This paper concerns 37 newborns who suffered clinical seizures from their 24th h till their 10th day of life, excluding post-anoxic seizures or convulsions leading to death. Continuous or repeated EEG recordings were performed for all babies: 25 infants had electro-clinical recorded seizures, 12 children did not have another convulsion after admission. This work allows us again to isolate a group of 18 newborns who presented the clinical and EEG features described as the 5th day seizures syndrome: term babies, appearance of first seizures between the 4th and 5th day, very frequent status epilepticus, almost constant inter-ictal 'sharp alternating theta' tracing, immediate spontaneously favourable evolution. A long-term follow-up was done on this group (18 children) and on the initially described group of 20 children: only 2 children had seizure recurrences, essentially febrile seizures, in spite of lack of long-lasting anticonvulsive therapy.

Brain↗

[Respiratory pauses in nocturnal sleep of infants].

In order to study the respiratory abnormalities during sleep that could select children with a high risk of sudden infant death syndrome (SIDS), 3 groups of children were studied: Group T: 18 control infants; Group G: 22 infants related to children who died from SIDS and group NM: 32 infants with near miss SIDS. A classic polygraphic EEG recording was performed during sleep. Apneas of 5 or more seconds and periodic respiration were analysed. Half of the infants in groups G and NM did not differ from those in group T. However, the groups G and NM differ from group T by a higher mean index of apneas during sleep and by the presence of a periodic respiration outside REM sleep in some of them. On the contrary, the mean duration of apneas and the number of apneas of more than 10 seconds did not seem to differ significantly in the 3 groups.

Female↗

[The diagnostic value of the EEG in peri- and intraventricular haemorrhage in the newborn (author's transl)].

EEGs were performed in 39 newborns with intraventricular haemorrhage (IVH) who subsequently died and compared with a series of 37 neonates who did not have an IVH. Abnormalities were more common in the IVHgroup. The most significant findings were the presence of electrical storms and that it was not possible to assess the gestational age. Positive rolandic spikes were not significantly more frequent in the IVH group. None of the EEG changes seem to be specific for IVH, but the presence of any of these in a premature infant makes an IVH highly probable.

Cerebral Hemorrhage↗

[Convulsions in the fifth day of life: a new syndrome?].

Among a series of 98 newborns who experienced neonatal seizures, 20 of them were individualized for they illustrated a "new syndrome": "the seizures of the fifth day of life". These patients were born at term, their maternal and natal history was unremarkable. Seizures always began around the fifth day and most often constituted a real electro-clinical état de mal. EEG reveals alternating sharpened theta waves, a pattern which seems to be characteristic. Some 6 days later, children recovered completely. Further evolution appeared to be always favorable. Although etiological enquiry remained negative, many facts suggested a viral etiology. This syndrome is probably frequent as it was also observed in other neonatal units.

Electroencephalography↗