Biomedical subjects

Y Naversten

Publications and source records attributed to Y Naversten.

14 recordsLinked to original sources

PubMed1984

Clinical comparison of bone scintigraphy with 99Tcm-DPD, 99Tcm-HDP and 99Tcm-MDP.

The bone-imaging agents MDP, DPD and HDP were compared radiochemically (only minor differences were found) in 12 patients with prostatic and 12 patients with breast carcinoma. Each patient received both MDP and either DPD or HDP. The scintigraphic examinations were compared visually and quantitatively. The uptake ratio normal bone/soft tissue was higher for DPD and HDP than for MDP. The ratio pathologic bone/normal bone was highest for MDP, particularly for prostatic carcinoma. The differences in this ratio for breast carcinoma were in general non-significant. The observed differences were minor and of little practical importance.

Aged↗

PubMed1983

Scintimetric evaluation of posttraumatic and postoperative growth disturbance using 99Tcm MDP.

Scintimetry with 99Tcm MDP was performed in 32 growth regions in 8 children with localized growth disturbances after surgery or injury. The results were compared with the simultaneously performed growth rate analysis using roentgen stereophotogrammetry. A quantitative and qualitative analysis of the nuclide bone images of the anterior view was performed. Numeric ratios, obtained by comparing count rate levels of injured or operated growth region with the corresponding contralateral region, are presented and a satisfactory correlation with the roentgen stereophotogrammetric growth rate analysis was found. Nuclide bone-imaging of growth regions at the knee and ankle provides valuable and significant information about growth and was found to be a clinically useful method when combined with standard radiographic techniques to evaluate growth conditions.

Adolescent↗

PubMed1983

Preoperative scintigraphy with correlation to cytology and histopathology in carcinoma of the thyroid.

At preoperative scintigraphy of 83 consecutive histopathologically confirmed thyroid carcinomas a solitary reduced uptake was observed in 70 per cent. The minimum detectable size was 10 mm for differential carcinomas showing this image, but in the 'screening group' of hereditary medullary carcinoma several scintigrams were considered normal despite a tumour size of 10 to 15 mm. In the imaging of the undifferentiated carcinoma a solitary reduced uptake with disappearance of the entire affected lobe was often demonstrated. Multifocal areas in the dot scintigram representing tumours were often missed at fine needle aspiration biopsy. Computer-processed scintigrams were superior in showing multifocal lesions.

Adenocarcinoma↗

PubMed1983

Total body potassium determination using a whole-body counter.

A scanning bed whole-body counter with two NaI(Tl) scintillation detectors was used for total body potassium determination with 40K for clinical application. For the calibration an in vivo dilution technique with 42K was used. The present counting method effectively minimised effects of redistribution and body build. For routine use the (W/H)1/2 calibration curve is suggested instead of the more complicated individual 42K calibration.

Body Composition↗

PubMed1976

Effect of splenectomy on anemia in patients on regular dialysis treatment.

Splenectomy was performed in 7 patients on regular hemodialysis treatment who had disabling anemia. All patients had a short 51Cr red cell survival time and an increased splenic uptake of red cells verified by external counting and computer-aided scintigraphy. The need for blood-transfusions was eliminated in all except one. In all patients the hemoglobin concentration rose after splenectomy. This was probably an effect of a reduced plasma volume and the removal of a large pool of non-circulating red cells. No consistent changes in the red blood cell survival time or the red cell volume were observed. The white cell and the platelet counts in the blood rose to twice the preoperative value. No adverse effect of the splenectomy was observed.

Adolescent↗

PubMed1974