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Biomedical subjects

Y Nosny

Publications and source records attributed to Y Nosny.

At least 19 recordsLinked to original sources

[32 cases of recurrent localized edema on return from the Tropics].

Thirty-two patients have been hospitalised in Marseilles since 1979 for recurrent oedema following their return from a tropical region. In spite of strong suspicion, the diagnosis of Loa loa was confirmed only five times. One patient was diagnosed with filariasis due to Mansonella perstans. The diagnosis of loiasis was usually presumptive and there were often wide variations in the laboratory findings. Two patients were thought to have an allergic reaction to diethylcarbamazine. Another patient was felt to have an allergy to streptococcal antigen. One patient who had lived in the Extreme Orient presented with an inflammatory fasciitis. Two patients presented with neurological manifestations: one with eosinophilic meningo-encephalitis, one with a neuropathy of the median nerve. In one case, the oedema was attributed to congenital lymphoedema.

Adolescent↗

[Association of sarcoidosis and primary biliary cirrhosis. Clinical and anatomopathologic study of a case followed for over 10 years].

A new case of primary biliary cirrhosis associated with sarcoidosis is reported in a 38 year-old woman. The diagnosis of sarcoidosis was based on the occurrence of cutaneous nodules, mediastinal lymph node enlargement, pulmonary reticular infiltrate, parotitis and diffuse arthritic pain, all disappearing after steroid therapy. Hepatic biopsy showed epithelioid-cell granuloma without necrosis. The diagnosis of primary biliary cirrhosis was made 6 years later as based on intrahepatic cholestasis associated with high titer of antimitochondrial antibodies and chronic destructive cholangitis. This association (5 other cases have already been reported) raises the problem of a possible link between the two diseases which could represent different patterns of a single immunological disorder.

Adult↗

[African trypanosomiasis of icterohemorrhagic form].

A case report of trypanosomiasis (T. rhodesiense), observed in a French tourist is described. The clinical picture associated a cytolytic hepatic jaundice, a thrombopenia with hemorrhagic manifestations, a renal insufficiency and secondarily a neutropenia with anemia. Moderate and transitory anomalies in the cerebrospinal fluid were noted. The cure was effectuated by administration of pentamidine.

Eflornithine↗

[Müllerian papillary adeno-fibromata and müllerian adenosarcomata. Mülleromas and mixed malignant müllerian growths contingent with benign epithelium (author's transl)].

The authors present 6 cases of müllerian papillary adeno-fibromata (or mixed mesodermal müllerian benign tumours) of which 4 are anatomo-clinical presentations and 2 are histological presentations, as well as 3 cases of müllerian adenosarcoma (mixed müllerian mesodermal tumour with stroma only sarcomatous). The study of these cases added on to those found in the literature leads to the following conclusions: The first group can be accepted. The second group will be of mild malignancy. All the same, 4 of which the sarcomatous nature is not in doubt at all (malignant from the start) recurred rapidly. Those in which the sarcomatous nature was attenuated or doubtful (15 cases) seemed to have a much longer evolution with some local recurrences. Only 3 patients have been followed up for more than 5 years. It is absolutely essential to carry out further observations before confirming for certain the prognosis of this new type of tumour.

Aged↗