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Biomedical subjects

Y Oshiumi

Publications and source records attributed to Y Oshiumi.

At least 19 recordsLinked to original sources
PubMed1995

Pancreatic enlargement in obstructive jaundice. Effects of biliary stream diversion in humans.

To verify the influence of obstructive jaundice on pancreatic growth, the anteroposterior width of the pancreas was measured by computed tomography in 30 cholangiocarcinoma patients excluded patients with distal bile duct tumor (jaundice group) and 74 control subjects. Follow-up examinations were performed on 12 patients with and without internal biliary drainage to elucidate the temporal relationship between pancreatic enlargement and the diversion of the obstructed biliary stream. Histologic analysis on autopsy samples from 13 control and 10 jaundice cases also was performed. Mean pancreatic head and body widths in the jaundice group were 2.93 +/- 0.3 cm and 2.01 +/- 0.3 cm, respectively. These values were significantly greater than those of the controls (2.13 +/- 0.3 cm and 1.49 +/- 0.3 cm, P < 0.01). The glandular widths returned to their normal sizes following internal biliary drainage. No changes were seen in patients who underwent external drainage alone. Histologic examination revealed that enlargement of the acinar cells or of the islet of Langerhans was often seen in the jaundiced patients. Therefore obstructive jaundice is thought to cause pancreatic growth through a trophic effect by interrupting biliary circulation.

Aged↗
PubMed1991

Salivary SPECT and factor analysis in Sjögren's syndrome.

Salivary SPECT and factor analysis in Sjögren's syndrome were performed in 17 patients and 6 volunteers as controls. The ability of SPECT to detect small differences in the level of uptake can be used to separate glands from background even when uptake is reduced as in the patients with Sjögren's syndrome. In control and probable Sjögren's syndrome groups the uptake ratio of the submandibular gland to parotid gland on salivary SPECT (S/P ratio) was less than 1.0. However, in the definite Sjögren's syndrome group, the ratio was more than 1.0. Moreover, the ratio in all patients with sialectasia, which is characteristic of Sjögren's syndrome, was more than 1.0. Salivary factor analysis of normal parotid glands showed slowly increasing patterns of uptake and normal submandibular glands had rapidly increasing patterns of uptake. However, in the definite Sjögren's syndrome group, the factor analysis patterns were altered, with slowly increasing patterns dominating both in the parotid and submandibular glands. These results suggest that the S/P ratio in salivary SPECT and salivary factor analysis provide additional radiologic criteria in diagnosing Sjögren's syndrome.

Adult↗
PubMed1990

Treatment of symptomatic non-parasitic liver cysts--surgical treatment versus alcohol injection therapy.

Fourteen patients with benign symptomatic non-parasitic cysts of the liver were either surgically treated, had alcohol injected into the cysts, underwent deroofing of the cyst or in 5, a cystectomy was done. Alcohol was injected into 6 patients and there has been no recurrence for as long as 5 years and 8 months after the treatment. Liver dysfunction occurred in 3 patients given blood transfusion during the surgery and/or postoperative course, an elevated temperature (over 39 degrees C) occurred in one patient. Adverse effects of alcohol injections were minor and transient. Based on our experience, the injection of alcohol is an effective treatment for benign symptomatic cyst of the liver. When a malignancy is suspected on imaging and/or cytologic studies, or when alcohol administration is ineffective, then surgery is indicated.

Adult↗
PubMed1990

[Effect of biliary obstruction and cholangitis on serum SPan-1 level].

We investigated the effect of biliary obstruction and cholangitis on serum SPan-1 level in 14 patients (5 patients with pancreatic cancer and 9 patients with biliary tract cancer) who were performed PTCD for biliary obstruction. 1 out of 5 cases with pancreatic cancer and 8 out of 9 cases with biliary tract cancer showed a decrease of SPan-1 level with improvement of jaundice. It suggested that the effect of biliary obstruction and cholangitis on serum SPan-1 level was much more in biliary tract cancer than in pancreatic cancer. There was no significant difference in changes of between serum SPan-1 level and serum CA 19-9 level after PTCD. We conclude that the effect of biliary obstruction and cholangitis on serum SPan-1 level is almost same on serum CA 19-9 level.

Antigens, Neoplasm↗
PubMed1982

67Ga scanning and upper gastrointestinal series for gastric lymphomas.

67Ga scanning and upper gastrointestinal (UGI) series were performed in 13 patients with gastric lymphomas before any treatment was initiated. Seven of these patients also underwent both examinations after completing chemotherapy and/or radiation therapy. Prior to treatment, all 13 patients had abnormalities on the UGI examination, and 12 of them had abnormalities on the 67Ga scans. In 6 patients, more extensive gastric abnormalities were demonstrated by 67Ga scanning than by UGI examination. Although persistent 67Ga uptake after treatment was indicative of relatively poor therapeutic response, lack of uptake did not always indicate a good response to treatment.

Aged↗
PubMed1982

[67Ga-emission computed tomography in bronchogenic carcinoma--a comparative study with conventional scintigraphy--].

Both conventional 67Ga scintigraphy and 67Ga emission computed tomography (ECT) were performed in 36 patients with bronchogenic carcinoma to evaluate clinical significance of 67Ga-ECT as an adjunctive method. Each patient received 111 approximately 185 MBq (3 approximately 5 mCi) of 67Ga-citrate intravenously. A rotation gamma camera (Shimadzu LFOV-E) was used for ECT study, and a gamma camera (Searle LFOV) was used for conventional scintigraphy. The detectability of 67Ga scintigraphy with ECT in primary tumors and regional lymph node metastases was compared retrospectively with that of conventional 67Ga scintigraphy alone. There was little improvement in detection of primary and metastatic lesions by adding 67Ga-ECT. Only 3 primary tumors were demonstrated more distinctly by 67Ga-ECT. However, there was no lesion which was detected only by 67Ga-ECT. Our data indicate that inclusion of 67Ga-ECT in the routine examination is unnecessary in cases with bronchogenic carcinoma.

Aged↗