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Biomedical subjects

Y Pourcelot

Publications and source records attributed to Y Pourcelot.

3 recordsLinked to original sources

Study of morphology of reactive dissolution interface using fractal geometry.

The determination of reactive fractal dimension was carried out using two forms of the Noyes-Whitney equation, -dQ/dt = K(Q/Q0)DR/3 and -dQ/dt = K'RDR-3 using the Richardson plot on the basis of previous data obtained by dissolution of an orthoboric acid powder. The correlation of the results provided by the two ways of calculation allows proposal of the hypothesis that dissolution begins on a specific population of reactive sites and probably promotes the formation of microporous volumes or cracks.

Microscopy, Electron, Scanning

[Particle state: divided solids and functionality].

Physical and physico-mechanical properties of powder particles, in the field of pharmacy, as drugs, excipients, microparticles and so on... are one of the main element in quality of dosage forms. The aim of this work is to insist on the importance of packing and rheological properties of divided solids and on his influence on compacting behaviour in drug development and industrial process, to avoid difficulties due to the variability of physical properties batch to batch. But as the physical quality of material raw is induced up to the crystallization operation, it is necessary to know, before, what use it will be done.

Elementary Particles