Biomedical subjects

Y Q Ye

Publications and source records attributed to Y Q Ye.

At least 19 recordsLinked to original sources

PubMed1994

[Relative DNA content and cycle distribution of cells in pleural effusions studied by flow-cytometry].

Pleural effusions from 28 patients were studied by cytology, chromosome and flow-cytometry. Relative cellular DNA content was measured. An estimate of ploidy as well as cycle distribution has been given. Eighteen patients suffered from malignant effusions while the rest had TB effusions. 83.3% of malignant effusion had aneuploid. The relative cellular DNA content and the cell cycle distribution can provide valuable and decisive information. The study of chromosome also help the diagnosis in addition to cytological results.

Adult↗

PubMed1994

[Changes in contents of aluminium, calcium and phosphorus contents of local bone after implantation of alumina endoprosthesis].

Thirty rabbits were divided equally into 5 groups randomly. A hole, 6mm in diameter and 2mm deep, was bored on both ilia of the thirty animals. Two cubes of alumina were implanted into the hole on one side of each animal, while the hole on the opposite side served as control. Six rabbits each were sacrificed on 10, 20, 40, 60 and 90 days after operation. Calcium, phosphorus and aluminium contents of bone tissues in and around both holes were determined by Inductively Coupled Plasma-Atomic Emission Spectrometry. The results show that the aluminium content of the bone tissues on the implanted side in each group was higher than that of the control with statistically significant difference in the 10-, 40- and 60-day groups (P < 0.05). This means that the implantation definitely releases aluminium into the bone tissues. On the contrary, calcium and phosphorus contents were significantly lower in the bone tissues on the implanted side than in the control side in the 10- and 20-day groups (P < 0.05-0.001). It implies that the aluminium released from the implant in the early stage can interfere with the metabolism of calcium and phosphorus and thus delay the mineralization of the bone tissues.

Aluminum↗

PubMed1993

[Effects of different dosage of PGE1 in pulmonary arterial hypertension].

The effects of different dosage of PGE1 on hemodynamics, oxygen delivery (DO2), oxygen consumption (VO2) and hemorheology in patients with pulmonary arterial hypertension (PAH) were investigated. In group 1, 10 cases were treated with PGE1 at a dosage of 20ng/kg.min-1, It was found that pulmonary arterial pressure (mPAP) and pulmonary vascular resistance (PVR) decreased by 23.3% and 38.7% respectively, CI and DO2 increased significantly; blood viscosity decreased significantly, but mean arterial pressure (MAP) and PaO2 were not affected. The side effects at such a dosage included flush of skin, headache and malaise. In group 2, 8 of the 10 cases were treated with PGE1 at a dosage of 40ng/kg.min-1. It was found that mPAP and PVR decreased by 22% and 40.4% respectively, CI increased significantly, MAP, systemic vascular resistance (SVR) and PaO2 decreased significantly while DO2 and VO2 changed slightly. The side effects at this dosage consisted of those occurring at the dosage of 20ng/kg.min-1 as well as hypotension and tachycardia. These results showed that PGE1 at a dosage of 20ng/kg.min-1 is effective, well-tolerated and yields less side effects.

Aged↗

PubMed1992

Local changes in aluminium, calcium and phosphorus content of bone caused by alumina implant.

Thirty rabbits were divided equally into 5 groups randomly. A hole, 6 mm in diameter and 2 mm deep, was bored on each iliac crest. Two pieces of alumina were implanted into the hole of one side, while the opposite side served as control. These rabbits were killed on 10, 20, 40, 60 and 90 days after operation. Calcium, phosphorus and aluminium contents of iliac bone on both sides were determined by Inductively Coupled Plasma--Atomic Emission Spectrometry. The results showed that the aluminium content of the implanted side in each group was higher than that of the control and difference was significant in 10, 40 and 60 day groups (P < 0.05). This shows that the implant releases aluminium into the bone. Moreover, the calcium and phosphorus contents were significantly lower on the implanted side than on the control side in 10 and 20 day groups (P < 0.05-0.001). Apparently, the aluminium released from the implant in the early stage can interfere with the local calcium and phosphorus metabolism and delay the mineralization of the bone.

Aluminum↗

PubMed1989

[Effects of ipratropium bromide (IPB) and its combination with salbutamol sulfate (SAS) in acute asthmatic attack].

34 patients with acute asthmatic attack were studied in double-blind, randomized and crossover manner. Each of them was treated with following two protocols during two sequential days: 0.5 mg of ipratropium bromide (IPB), followed by 5 mg of salbutamol sulfate (SAS) 75 minutes later; or 5 mg of SAS, followed by another dose 35 minutes late. The drugs were delivered via a jet nebulizer. The effects and side-effects of the treatment were evaluated immediately before the first inhalation and at peak of bronchodilatation (60-75 minutes after IPB or 20-35 minutes after SAS). Compared with inhaled SAS, IPB produced considerable improvement in central airway parameters such as forced expiratory volume in one second (FEV1) peak expiratory flow (PEF) and respiratory resistance (Rrs) (P greater than 0.05), but less improvement in peripheral airway parameters such as forced vital capacity (FVC) and maximal mid-expiratory flow (MMEF) (P less than 0.01). The sequential inhaled SAS after IPB improved all five parameters (P less than 0.01), but the repeated dose of SAS increased only MMEF (P less than 0.01). Compared with double-dose SAS, the sequential treatment with IPB and SAS 1 ed to considerable improvement in FVC and MMEF (P greater than 0.05), but greater improvement in FEV1, PEF and Rrs (P less than 0.01). Heart (rate and tremor scores after two doses of SAS increased significantly (P less than 0.01). It is concluded that IPB alone is less effective than beta-adrenoceptor agonist, but its combination with SAS would be an effective and safe treatment in acute asthmatic attack.

Adult↗

PubMed1988

Rapid detection of pneumococcal antigens in sputa in patients with community-acquired pneumonia by coagglutination.

This paper introduces the clinical use of coagglutination as a method for the rapid detection of pneumococcal antigens in patients with community-acquired pneumonia and compares it with the sputum Gram stain and culture methods. Among 105 patients, 50 (48%) were diagnosed as having pneumococcal pneumonia by at least one of the three methods. Of 95 sputa tested, 44 (46%) were found to be positive by the coagulation test, 26 (27%) by Gram staining and only 16 (17%) by the bacterial culture method. The rate of detection of pneumococcal antigens was thus greater with coagulation than with either of the other two methods. The differences were very significant (both P less than 0.01). Our study indicates that the advantages of coagglutination over the traditional bacteriological methods are its speed, sensitivity, convenience and also its relative independence of antibiotic therapy. It thus provides a new dimension in the aetiological diagnosis of pneumococcal pneumonia.

Adult↗

PubMed1987