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Biomedical subjects

Y R Bai

Publications and source records attributed to Y R Bai.

4 recordsLinked to original sources
PubMed1994

[Hemodynamic study on nitroglycerin compared with Salvia miltiorrhiza].

UNLABELLED: This report investigated the hemodynamic changes of both nitroglycerin and Salvia miltiorrhiza (Co.) concerning pulmonary capillary-wedge (PCW), mean pulmonary artery pressure (MPAP), cardiac output (CO), cardiac index (CI), systemic mean pressure (SMP), and heart rate (HR). In 20 patients with heart diseases of normal cardiac function, nitroglycerin were compared with Salvia miltiorrhiza (Co.) using Swan-Ganz Catheter, which were self-compared. RESULT: (1) Both drugs had the similar vaso-dilating effects, reduced the filling pressure of left ventricle and increased the cardiac output but different in the time of appearance and duration, particularly concerning CO and CI. (2) The effect of Salvia miltiorrhiza (Co.) was markedly superior to the nitroglycerin. The action of former was more persistent and the improvement of cardiac function was better than that of latter.

Adult↗
PubMed1989

[Therapeutic effects of nifedipine in pulmonary hypertension secondary to congenital heart disease].

The hemodynamic effects of nifedipine in 15 patients with pulmonary hypertension (PH) secondary to congenital heart disease (CHD) were evaluated. The basal hemodynamic parameters were obtained before medication. The parameters were also obtained 60 minutes and 2 months after taking nifedipine. After treatment, PAPs were decreased 18% and 15% (P less than 0.01), PAPd 21% and 24% (P less than 0.01), PAPm both 19% (P less than 0.01), respectively. TPR were reduced 33% and 30% (P less than 0.01). SAP decreased slightly after 60 minutes. HR, CO and CI remained unchanged. Of the 10 patients suffering from hyperkinetic PH, 8 patients underwent closure of defects after treatment of nifedipine. The above results suggest that nifedipine is effective for patients with PH secondary to CHD. It acted as an antihypertensive agent in patients with CDH associated with hyperkinetic PH before operation.

Adolescent↗