Biomedical subjects
Publications and source records attributed to Y R de Miguel.
A new polymer-supported chromium porphyrin has been prepared and fully characterised; its catalytic activity and recyclability were investigated for the ring-opening copolymerisation of 1,2-cyclohexene oxide (CHO) and carbon dioxide (CO2).
Efficient methods for the preparation of combinatorial libraries of receptors have been reported recently and, in most cases, these have led to the identification of host-like molecules that bind a particular substrate selectively. Dynamic libraries of macrocycles have also been synthesised that could open the way to a new selection approach to receptors and catalysts.
There are many new analytical techniques for the characterization of resin-bound substrates and solid-phase reaction monitoring. The aim of this review is to focus on applications of the different IR techniques used in solid-phase synthesis highlighting some of the recent advances in the field that allow us to obtain more than just the usual qualitative information. Many examples will be discussed where these new IR techniques have been used for mechanistic and kinetic studies of solid-phase reactions.