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Biomedical subjects

Y S Lim

Publications and source records attributed to Y S Lim.

66 records · Page 4Linked to original sources
PubMed1982

Enzyme-linked immunosorbent assay for the diagnosis of recent rubella infection.

This paper presents further evidence of the sensitivity and reproducibility of ELISA for the detection of rubella antibody. This test can also be extended to include the diagnosis of recent rubella infections once the index of significance has been computed based on the estimated ELISA ratio of absorbance between the acute and convalescent serum samples. There is a greater than 90% agreement when compared to the results obtained by the haemagglutination-inhibition test. It should be further evaluated for rubella using purified rubella antigen to increase sensitivity and reproducibility.

Antibodies, Viral↗
PubMed1982

Enterotoxin production by Staphylococcus aureus strains isolated from humans, foods and animals in Malaysia.

Enterotoxin production by strains of Staphylococcus aureus isolated from human, food and animal sources was investigated. Of the 130 isolates studied, 27 (20.8%) were found to be enterotoxigenic. The most common enterotoxin detected from human sources was enterotoxin C whereas enterotoxin B occurred more frequently in staphylococcal strains of food origin. The 2 enterotoxigenic strains, from animals isolated from a dog and a goat, produced enterotoxins A and C, respectively. Enterotoxin E was not detected alone from any of the enterotoxigenic strains studied, but occurred together with other enterotoxins. The need to detect enterotoxin in staphylococcal strains and in suspected foods for the confirmation of staphylococcal food poisoning is discussed.

Animals↗
PubMed1982

Antibiotic resistance and R plasmids in coliforms isolated from some Malaysian cooked foods.

Forty samples of Malaysian cooked foods were examined for the presence of antibiotic-resistant coliforms and R plasmids. Twenty seven (68%) of the foods had antibiotic-resistant coliforms and 5 (13%) had R plasmids. Nineteen samples (48%) had total bacterial counts over 10(6) per gm and in 5 samples, no coliforms were detected. Our findings show that cooked food may be one possible way by which R plasmids are spread. The control of the spread of R plasmids is discussed.

Anti-Bacterial Agents↗
PubMedDate not supplied

Nicardipine versus nitroprusside infusion as antihypertensive therapy in hypertensive emergencies.

This prospective study compared the efficacy of nicardipine and nitroprusside for treating hypertensive emergencies by measuring haemodynamic indices and serum catecholamine levels. Patients admitted to the emergency department with a hypertensive crisis and acute pulmonary oedema received intravenous infusions of nitroprusside (starting dose 1 microgram/kg per min, n = 20) or nicardipine (starting dose 3 micrograms/kg per min, n = 20). Both groups experienced significant declines in systolic and diastolic blood pressure after treatment, but there were no significant time-dependent differences between the groups. Heart rate decreased in the nicardipine group and increased in the nitroprusside group, but neither change was significant. Respiration rate decreased and capillary oxygen saturation rate increased after treatment in both groups. Adrenaline and noradrenaline levels decreased significantly after treatment in both groups; noradrenaline levels were significantly decreased in the nicardipine-treated group compared with the nitroprusside-treated group. Injectable nicardipine is easy to use and as effective as nitroprusside for treating hypertensive crisis with acute pulmonary oedema.

Aged↗