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Y Takahira

Publications and source records attributed to Y Takahira.

9 recordsLinked to original sources
PubMed1998

The clinical advantages of editable real-time volume rendering in a medical virtual environment: VolMed.

Segmentation for a medical virtual environment is a process of image diagnosis. It should be performed by clinical doctors, otherwise the data may be meaningless for using clinical purposes. At the National Cancer Center, in Japan, we have recently developed interactive, editable real-time volume rendering software (VolMed), based on Volren-6 software, with the ability to interactively edit the 3D images of a patient's virtual cancer and virtual organs, in a virtual environment. Doctors can see proposed solutions to clinical problems as 3D images, using real-time volume rendering. We conclude that interactive editing is very important for clinical use, and also decreases the time required to create the virtual cancer images used for surgical simulation, pre-surgical planning and 3D invasion diagnoses.

Algorithms↗
PubMed1975

[Therapeutic effect of sulfobenzyl-penicillin (SB-PC) on the concentration of SB-PC in human bile (author's transl)].

Sulfobenzyl-penicillin (SB-PC) is currently being investigated for use in man. The purpose of this study was to evaluate effect of SB-PC on Salmonella typhosa and biliary excretion of SB-PC in disease of the biliary tract. 1) Clinically, typhoid carriers without cholelithiasis were initiated with 4.0 g/day of SB-PC. Stool and bile became negative for Salmonella typhosa 14 days after initial treatment. 2) In typhoid carriers with cholelithiasis, Salmonella typhosa were not isolated from bile, wall of the gallbladder and surface of gallstone, but were isolated from nuclei of gallstones. The treatment of typhoid carriers with cholelithiasis may belong to a most difficult problem. 3) Biliary excretion of SB-PC in the patient given a single dose of 2.0 g/day im. was markedly dependent on characteristics of the patient, situation of external drainage and volume of bile excretion. High concentration in bile in some patient was 298 mug/ml at 3 hours after administration. 4) In intravenous administration of single dose of 6.0 g. maximum concentration in bile was about 2,000 mug/ml at 2 hours after administration and bactericidal concentration was obtained for resistant bacteria (Pseudomonas, Proteus, etc.) in biliary infection. 5) As side effects, pain and redness were infrequent after im. administration. Toxicity was not experienced in the patients injected intravenously.

Aged↗
PubMed1967

Studies on cholera carriers.

Cholera carrier studies in the Philippines in 1964-66 showed a prevalence rate of 21.7% among household contacts of cholera patients, and 8.4% in occupants of houses next door to one where a cholera patient lived, as opposed to 0.34% in the general population. The duration of the carrier state among 19 household carriers isolated for examination varied from 5 to 19 days. The vibrio concentration in the stool of contact carriers was 10(2)-15(5) per gram, as compared with 10(6)-19(9) per ml of rice-water stool in cholera cases.The agglutinin titre increased with time for carriers, as it does for patients. It declined to a very low level 8-12 weeks after recovery, with the exception of one proved long-term carrier.The strains isolated from carriers were identical in all respects, including virulence in infant rabbits, with strains isolated from patients-except that 3 carrier strains were rough.

Adolescent↗
PubMed1967

Observations on cholera treated orally and intravenously with antibiotics. With particular reference to the number of vibrios excreted in the stool.

In order to determine the effect of antibiotics on the course of cholera, precise observations of clinical symptoms and quantitative examination of vibrios in the stool were carried out on 17 patients with cholera El Tor from the Philippines. Seven patients were treated orally with kanamycin, tetracycline, chloramphenicol or erythromycin, 7 intravenously with chloramphenicol or tetracycline, and 3 were not given any antibiotic.Both the oral and the intravenous routes of administration of the antibiotics were suitable for shortening the period of diarrhoea and reducing the excretion of vibrios in the stool.The number of vibrios in 1 ml of watery stool during the first day of illness was about 10(8) in every case. There was marked reduction in the number within 1 hour, and complete disappearance of vibrios within 10 hours, of the start of treatment in most cases. However, vibrios reappeared later in some cases.Kanamycin, a non-absorbable antibiotic, was found to be less effective than adsorbable antibiotics such as chloramphenicol and tetracycline.

Adolescent↗