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Biomedical subjects

Y Y Shiau

Publications and source records attributed to Y Y Shiau.

At least 19 recordsLinked to original sources

Natural frequency assessment of stability of root keeper magnetic devices.

The aim of the study was to evaluate the potential for using natural frequency (NF) as an indicator for assessing the stability of a magnetic keeper device used in prosthodontic treatment. A three-dimensional finite element (FE) model of a root keeper-cement-dentine system was established for NF analysis. The model was first validated against a series of in vitro experiments. Then, NF values of the first vibrational mode of the FE model with various boundary conditions were calculated. The in vitro results showed that the measured NF values of the root keeper-incisor units decreased significantly (p<0.01) from 9.07 +/- 0.37 to 5.73 +/- 0.10 kHz when the units were embedded in simulated bony tissue. Results obtained from FE simulations demonstrated that the root keeper would fully loosen when the constant values of the spring elements were lower than 10(4) N-m(-1). Furthermore, a linear increase in the NF values of the model was observed from 6.16 to 15.52 kHz, when the constant was increased from 10(4) to 10(7) N-m(-1), and the values then reached a plateau. The results indicate that the NF value of a root keeper has the potential to be used for monitoring the stability of such a device.

Biomechanical Phenomena↗

The effects of masseter muscle pain on biting performance.

The present study applied a standardized test food of known hardness to evaluate the biting performance of 20 female patients who had pain mainly in the masseter muscle during palpation. Another 20 women of a similar age group who were pain-free during examination served as controls. Electromyograms (EMG) of the masseter and sternocleidomastoid (SCM) muscles and the jaw position were recorded and measured when the subjects were biting through two types of test foods with known hardness (hard type, 20 kg hardness and extra-hard type, 60 kg hardness). Pressure-pain-threshold (PPT) values of both the patients and the normal subjects were obtained with an algometer. It was found that the PPT of the patients with pain was significantly lower and that the extra-hard food took more masseter muscle activity and more working side jaw movement in both the pain and the normal groups. During both hard and extra-hard food biting, a significantly longer duration of masseter muscle activity was found in pain patients while the total muscle activity was not significantly stronger. Strong correlation existed between SCM and masseter muscle activity during both hard and extra-hard food biting in the patient group, while such correlation was very weak in the normal group. In conclusion, painful masseter muscles required longer masseter and SCM muscle contraction time for breaking through a hard food of 20 kg and more, and co-activation of SCM and masseter muscles existed and was more evident when the food was harder or the pain was more severe.

Adult↗

Structural influence of hanatoxin binding on the carboxyl terminus of S3 segment in voltage-gated K(+)-channel Kv2.1.

The voltage-sensing domains of voltage-gated potassium channels Kv2.1 (drk1) contain four transmembrane segments in each subunit, termed S1 to S4. While S4 is known as the voltage sensor, the carboxyl terminus of S3 (S3C) bears a gradually broader interest concerning the site for gating modifier toxins like hanatoxin and thus the secondary structure arrangement as well as its surrounding environment. To further examine the putative three-dimensional (3-D) structure of S3C and to illustrate the residues required for hanatoxin binding (which may, in turn, show the influence on the S4 in terms of changes in channel gating), molecular simulations and dockings were performed. These were based on the solution structure of hanatoxin and the structural information from lysine-scanning results for S3C fragment. Our data suggest that several basic and acidic residues of hanatoxin are electrostatically and stereochemically mapped onto their partner residues on S3C helix, whereas some aromatic or hydrophobic residues located on the same helical fragment interact with the hydrophobic patch of the toxin upon binding. Therefore, a slight distortion of the S3C helix, in a direction toward the N-terminus of S4, may exist. Such conformational change of S3C upon toxin binding is presented as a possible explanation for the observed shift in hanatoxin binding-induced gating.

Animals↗

Fabrication of conventional complete dentures for a left segmental mandibulectomy patient: a clinical report.

Without preprosthetic reconstructive surgery, denture fabrication for mandibulectomy patients becomes extremely difficult. Implant-assisted overdentures may improve denture retention and stability, but some patients cannot afford this treatment. For the segmental mandibulectomy patient described in this report, properly fabricated conventional complete dentures provided comfort and sufficient function.

Aged↗

Measurement of the size and orientation of human masseter and medial pterygoid muscles.

To gain a better understanding of biting and chewing performance, the size and orientation of the masseter and medial pterygoid muscles in living humans were studied. Twenty-seven young males having complete dentition, class I dental occlusion and normal muscle and jaw function were examined using magnetic resonance images of the head between the zygomatic arch and hyoid bone. The sections were parallel to the palatal plane, and the thickness was 3 mm without a gap. A computer software program (Medical Dental Image, MDI) was developed to identify and calculate the area of each cross section of the muscle, and the volume of the muscle was then estimated. The axis of the muscle was determined by connecting the centroids of the sections in the lower and upper 1/3 of the whole muscle. The effective muscle cross section area was then calculated by resectioning the muscle perpendicularly to the muscle axis. It was found that the mean masseter muscle volume was around 31 cm3, and that the mean medial pterygoid muscle volume was 11 cm3. Their mean effective cross section areas were around 6.2 cm2 and 3.5 cm2, respectively. The axis of the masseter muscle was more perpendicular to the palatal plane and parallel to the sagittal plane than was the medial pterygoid muscle. The results suggest that the use of magnetic resonance images (MRI) is an effective noninvasive measurement technique for determining the size and orientation of masseter and medial pterygoid muscles. This technique can be employed in future studies on human bite force evaluation and masticatory function.

Adolescent↗

Three-dimensional modelling of the catalytic domain of Streptococcus mutans glucosyltransferase GtfB.

Glucosyltransferases (GtfB/C/D) of Streptococcus mutans, a pathogen for human dental caries, synthesize water-insoluble glucan through the hydrolysis of sucrose. Genetic and biochemical approaches have identified several active sites of these enzymes, but no three-dimensional (3D) structural evidence is yet available to elucidate the subdomain arrangement and molecular mechanism of catalysis. Based on a combined sequence and secondary structure alignment against known crystal structures of segments from closely related proteins, we propose here the 3D model of an N-terminal domain essential for the sucrose binding and splitting in GtfB. A Tim-barrel of (alpha/beta)(8) structural characteristics is revealed and the structural correlation for two peptides is described.

Amino Acid Sequence↗

Evaluation of biting performance with standardized test-foods.

Human masseter muscle is the main power source used for crushing or grinding the foods. Its size is regarded as an determining factor of chewing force and function. A system of measuring the masseter muscle volume from MR images was developed in this study. For a better understanding of the masseter muscle function, a standardized test-food developed in our laboratory was used. Twelve male subjects having complete dentition and healthy masticatory function were used to chew the test-foods. The EMG muscle activity of the masseter muscle during breaking and chewing the test-foods was observed. It was found that the muscle volume was positively related to the body size. The increase of the muscle activity during breaking and chewing was almost parallel to the increase of the test-food hardness, and the increase was mostly in the duration of muscle contraction. It was concluded that the measurement of masseter muscle volume is possible, and our test-foods can be used for chewing function examination with high reliability. Within a certain level of hardness, harder food requires longer muscle contraction time instead of stronger muscle force to break and chew the food.

Adult↗

Dentistry in Taiwan, Republic of China: national health insurance reforms, illegal dentistry and plans for peer review quality control.

The dental health care system in Taiwan, Republic of China is described in terms of demographics, structure, context of treatment and historical development of the dental health care payment system. A notable characteristic of the system is the existence of trade dentists, who operate without licensure. Their popularity and price advantage has maintained a political base that affects policy decisions. Health care reforms of March, 1995 with a comprehensive national health insurance, as well as ambitious plans for systematic peer review quality control of dentists' work are unique health care developments worthy of the attention of health care policy makers in other countries who are studying health care reform processes.

Adolescent↗

The importance of determination of jaw position in orthodontic diagnosis and treatment planning for adult patients.

The basic data needed for orthodontic diagnosis and treatment planning include color prints of soft tissue facial profile, intraoral dental arches, and occlusion; cephalometric and panoramic radiographs; and dental casts. Hand-wrist and TMJ radiographs are also necessary in some circumstances. If orthodontic diagnosis and treatment plans are made only from the dental alignments and occlusion from the static or hand-assembled dental casts, the diagnosis and treatment planning made may be wrong in some cases. Clinically, it is necessary to find the centric relation of the lower jaw and to transfer the jaw relationship to the articulator. Correct diagnosis and orthodontic treatment planning may then be made from the findings of the occlusal relationship from the articulator accompanied with the information on skeletal age and craniofacial characteristics from the hand-wrist and cephalometric radiographs. Four clinical cases have been presented to demonstrate the importance of determination of jaw position in orthodontic diagnosis and treatment planning in adult patients.

Adult↗

Vertical distortion in distal extension ridges and palatal area of casts made by different techniques.

A coordinate measurement machine with laser probe was used to measure the vertical distortion of the casts produced by use of three types of impression materials (irreversible hydrocolloid, condensation silicone, and addition silicone) and two types of trays (stock and custom trays). Results indicated that all impression groups showed positive vertical distortion (ranging from 0.00566 to 0.30299 mm) at the edentulous ridges and palatal area. The amount of the vertical distortion was greatest at the palatal area and was followed by the high edentulous ridge and the low edentulous ridge. Addition silicone, with either custom tray or stock tray, was the most accurate impression material. Condensation silicone was more accurate than irreversible hydrocolloid in custom tray impression. However, in stock tray impression the irreversible hydrocolloid was more accurate than the condensation silicone. The results suggest that, with careful manipulation, irreversible hydrocolloid with stock tray impression may provide a satisfactory cast for fabricating the framework of a distal extension removable partial denture.

Alginates↗

Observation of bolus position with standardized test foods and fluoroscopic technique.

Sugar and agar balls containing barium were made for the fluoroscopic observation of the bolus position during habitual side chewing in 13 adult males (aged from 20 to 28 years) who had a complete dentition and healthy masticatory system. The test foods had constant size, shape, weight and known hardness, i.e. type 1, 20 kg; type 2, 40 kg; type 3, 1.0 kg and type 4, 0.5 kg. These four types of test foods were chewed randomly in a fluoroscopic room. The jaw separation distance and the bolus position during first bite and crushing bite were observed. The influence of the chewing order of four types of test foods on the bolus position was also recorded. It was found that both hard and soft test foods were most often crushed at the first molar area, and the separation distance during the crushing bite was only slightly wider than the diameter of the food. The first bite jaw separation distance for hard food chewing was significantly wider than soft food chewing and the later in the chewing order the wider the separation distance. The effect of chewing order was not significant on the position and jaw separation distance of the crushing bite.

Adult↗

Fear of injections and report of negative dentist behavior among Caucasian American and Taiwanese adults from dental school clinics.

Fear of injections and reports of negative dentist behavior and associations with dental anxiety and avoidance of treatment were explored among 951 adults from dental school clinics in Iowa City, Iowa and Taipei, Taiwan. Use and fear of anesthetic injections and negative dentist behavior were assessed by written questionnaire to test associations with demographics, overall dental anxiety (Dental Anxiety Scale or "DAS") and utilization behaviors. Frequency and logistic regression analyses showed that use of dental anesthetics for routine treatment was much greater overall among caucasian Americans than Taiwanese, as was fear of injections. Taiwanese and Americans with high dental anxiety (DAS 12) had similar high fear of injections, but inspite of similar fears about dental drilling, high anxiety Taiwanese reported using much less local anesthesia for routine treatments than did high anxiety Americans. Report of condescending remarks to patients ("put downs") by dentists was mainly an American phenomenon associated with high dental anxiety. Avoidance of appointment making was high for persons afraid of injections and for Americans reporting negative dentist behavior. Avoidance was highest in subjects with high dental anxiety. That predominant characteristics or etiologies of dental anxiety can differ by cultural differences in dental health care systems, dentist beliefs and/or expectations of patients within those systems was discussed in relation to the literature.

Adolescent↗

Effect of working side interferences on mandibular movement in bruxers and non-bruxers.

The effect of working interference on 13 bruxers and 14 non-bruxers was studied by applying a metal overlay on the buccal cusps of the adjacent upper premolar and molar. The pattern and velocity of cyclic movement during gum chewing before and after overlay insertion were observed. EMG of the temporalis and masseter muscles were recorded bilaterally during the chewing movement. It was found that after insertion, one of the non-bruxers complained of pain in the muscles, while such a complaint was not found in bruxers. Bruxing habit was reported to be less or eliminated in 44% of the bruxers, but no non-bruxers became bruxers. The closing velocity was more often decreased immediately after overlay insertion, and the closing path near the occlusal phase was significantly narrower, with patterns of over-extension and avoidance before reaching the occlusal phase. The delayed effects were a more vertically oriented chewing cycle without over-extended closing movement, and an unretarded chewing velocity. It was concluded that within the experimental period a working side interference was tolerable in most of the subjects studied with or without a bruxing habit.

Adolescent↗

The effects of dental condition on hand strength and maximum bite force.

Piezoelectric force transducer and hand dynamometer were used for measuring the maximum bite force and hand grasp force on 2034 primary, middle, and high school students. Dental condition and body weight and height were also observed to relate to the force measurements. It was discovered that both forces increased relative to the increase of age, body weight, and body height. Boys had stronger bite force than girls at all age groups, while the grasp force of boys became significantly stronger only after the age of 13. Students who had dentition with decay and missing teeth tended to have weaker bite force, while hand force was not influenced. Bite force does not seem parallel to hand strength and is, instead, related to dental condition.

Adolescent↗

An epidemiological study of temporomandibular disorders in university students of Taiwan.

A total of 2033 university students were surveyed for the prevalence of TMD in Taiwan. It was found that 42.9% of the students had one or more signs related to TMD, and females were slightly more frequently found. Clicking of the joint was the most common sign. Occlusal factors such as balancing contact, dental restoration, molar guidance in eccentric movement, etc., were more often found in the TMD group. Scores on stress, general anxiety, emotion and anger were higher in the TMD group while tension, ambition, depression, competition and test anxiety were not as significant. Although the prevalence of TMD in this population is high, the severity and treatment demands are low.

Adolescent↗

Effects of working side interference on nocturnal bruxers.

The present study aimed to test the effects of experimentally placed working side interference on nocturnal bruxers with regard to the health and chewing motor behaviors of the masticatory system. Thirteen asymptomatic nocturnal bruxers, nine males and four females, aged 18-31 years old, were selected according to the including criteria. A metal overlay was fabricated and bonded on the tips and lingual inclines of buccal cusps of the upper second premolar and first molar of the habitual chewing side. It discluded the eccentric contacts without disturbing the centric occlusion. A light emitting diode system was used to record the chewing motor behaviors before (W0), immediately after (W1), one day after (W2), one week after (W3), and one month after (W4) placement of the working side interference. The healthy states of masticatory muscles and TMJs were examined at each session. The results showed: 1. High overlay debonding rate (60%). Among five subjects who were observed over 25 days, 80% showed grinding facets, and 40% showed grade I mobility on the overlay opposing teeth. None of the subjects complained of muscle or joint pain in the one month follow-up period. 2. The chewing movements shifted toward the non-interfered side with narrowed and vertical chews after placement of overlays. Two major responded chewing patterns were found according to the results of statistical analysis. 3. Sixty-nine per cent of the subjects showed higher mean closing velocity than the mean opening velocity at the W0 session.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Body posture and hand strength of patients with temporomandibular disorder.

The aim of this study was to observe the difference between patients of craniocervical muscle pain and nonpatients in head-neck posture, masticatory muscle activity, and the force exerted by the hand. Fifty-one patients and 28 nonpatients were observed. The electric activity of the masseter muscles was recorded when the subjects were doing pinching or grasping with the jaw in positions of rest, clenched, and clenched with gauze. Measurement of right and left tilting or extension and flexion of the head and neck was made from photographs of frontal and lateral views. It was found that the pinching and grasping force was much stronger in men than in women and in nonpatients than in patients with pain. The pinching and grasping force was more powerful with the teeth clenched. Clenching with gauze did not increase, but more often decreased the strength of the hand. The activity of the masseter muscle during clenching was about 10 to 26 times that of the resting activity. The activity decreased slightly when clenching with pinching or grasping. Patients were more likely to have a stretched neck with more extension of the head. Their masseter muscle activity and hand force were significantly weaker than that of the nonpatients.

Adult↗