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Biomedical subjects

Y Yassur

Publications and source records attributed to Y Yassur.

At least 19 recordsLinked to original sources
PubMed1992

Diurnal intraocular pressure variations: an analysis of 690 diurnal curves.

Out of a total of 2272 diurnal curves (DC) of intraocular pressure (IOP) obtained from 1178 patients 690 first curves of the right eye of all patients were analysed. For each DC there were 4-6 IOP readings taken between 8 am and 6.30 pm of the same day. The patients' diagnosis, age, sex, type of IOP lowering medication, diabetes, and the calendar month of the year were recorded. In 40% of cases the highest IOP was found at the earliest morning measurement with some 65% of peaks occurring before noon. The lowest IOP measurement showed no specific predilection for any particular time of the day. These findings were true for all diagnosis groups. The mean range of IOP fluctuation during the DC was 5.0 mm Hg in normals, 5.8 mm Hg in patients with open angle glaucoma (OAG), and 6.8 mm Hg in patients with ocular hypertension (OHT). Patients treated with timolol had a lower mean IOP fluctuation range than those on other types of IOP lowering treatment. No association was found between all other parameters examined and the diurnal IOP distribution.

Adrenergic beta-Antagonists↗
PubMed1992

Analysis of autoantibodies among patients with primary and secondary uveitis: high incidence in patients with sarcoidosis.

The sera of 122 patients with uveitis were examined for the presence of various antinuclear autoantibodies. Overall 21.3% of the patients had antibodies to ribonucleoprotein (RNP) and 18% to Ro (SSA). When subdividing the patients according to primary uveitis versus secondary uveitis, the autoantibodies were detected more frequently in the second group [anti-RNP 13.3 vs. 31.4%, anti-Ro (SSA) 11.8 vs. 27.7%, anti-Sm 10.3 vs. 24% and poly (G) 2.9 vs. 14.8%, respectively]. No differences could be asserted in autoantibody frequencies according to disease location within the uvea. Among uveitis patients afflicted with sarcoidosis a particular high incidence of autoantibodies was detected in comparison with all other subgroups of patients with uveitis. Although the presence of autoantibodies among patients with uveitis appears not to have a major diagnostic value, their assessment may aid to a better understanding of disease pathogenesis.

Antibodies, Antinuclear↗
PubMed1992

Spontaneous hyphema: an unusual complication of uveitis associated with ankylosing spondylitis.

Two patients with ankylosing spondylitis (AS) and recurrent uveitis had rubeosis iridis each with an episode of spontaneous hyphema. Rubeosis iridis has been reported to occur in some cases of uveitis, but it has not been seen in those associated with AS. We suggest that AS be included among the conditions that can lead to the development of rubeosis iridis, with consequent silent hyphema.

Adult↗
PubMed1992

Unilateral atypical retinal pigment epitheliopathy associated with serous retinal detachment.

We treated a young patient with unilateral gray-yellow subretinal lesions associated with bullous retinal detachment in the posterior pole. Angiography revealed the presence of multiple areas of subretinal pigment epithelial pooling of the dye. It is rare to find an association between acute inflammation of the retinal pigment epithelium and sensory retinal detachment.

Adult↗
PubMed1992

Senior's syndrome (hereditary renal retinal dysplasia) associated with cataracts.

Senior's syndrome includes nephronophthisis with retinitis pigmentosa. In our patient, there was a combination of bilateral retinitis pigmentosa, cataracts, nephronophthisis, osteomalacia, growth and mental retardation, arterial hypertension, and aortic insufficiency. This case was unusual because all the features of Senior's syndrome existed along with bilateral cataracts from childhood.

Adult↗
PubMed1992

Choroidal melanoma with massive lipid exudation in a patient with metastatic hypernephroma.

A 75-year-old woman with diffuse metastatic hypernephroma had a unilateral total exudative retinal detachment associated with a big choroidal mass. In addition, multiple yellow-white intra- and subretinal deposits were seen around the tumor. These findings and the patient's medical history led us to think of choroidal metastatic hypernephroma with intraocular spread. However, histopathologic examination revealed the presence of epithelioid malignant melanoma of the choroid with numerous retinal and subretinal lipid deposits and lipid-laden macrophages. This picture of massive lipid exudation is rare in untreated choroidal melanomas.

Aged↗
PubMed1991

Graves' orbitopathy and restrictive myopathy.

Restrictive myopathy in Graves' orbitopathy is a disabling disorder, difficult to treat, involving clinically the inferior and medial recti. Most patients do not return to the normal, premorbid state of muscular alignment and the goal of treatment is to reach binocular vision in the important directions of gaze--straight ahead (primary position) and downgaze (reading position). The treatment in the acute, congestive stage is optical, prisms or patching, or medical. The medical treatment principally consists of a course of oral or intravenous corticosteroid treatment, and in selected patients orbital irradiation can be of benefit. Surgery is performed on the euthyroid patient after the muscular imbalance has stabilized, usually six months from the onset of the disorder. The mainstay of therapy is a large recession of the involved muscles, if possible on an adjustable suture. Sometimes marginal myotomies are added to the muscle recession. A fadenoperation on the contralateral, minimally involved inferior rectus has been suggested as a means of increasing muscular alignment in both primary position and downgaze. Thorough evaluation of the course of the disease, and the benefit of different treatment modalities is possible only with long term follow-up.

Graves Disease↗
PubMed1991

Extensive fibrous downgrowth after traumatic corneoscleral wound dehiscence.

Two months after cataract surgery, subconjuctival would gaping developed in our patients as a result of trauma and was resutured. Subsequently, corneal edema and a retrocorneal membrane were noticed. During penetrating keratoplasty, a thick fibrous membrane was found growing from the posterior corneal surface into the anterior and posterior chambers. Histopathologic studies revealed fibrous down-growth from the corneal stroma through a gap in Descemet's layer, forming a retrocorneal membrane.

Aged↗
PubMed1990

[Recurrent episodes of central retinal artery occlusion].

A 70-year-old man with arteriosclerosis of the carotid arteries developed acute occlusion of the central retinal artery and blindness during intravenous pyelography. 40 minutes after the occlusive episode he underwent paracentesis of the anterior chamber and vision returned (6/18). During the next 2 weeks, while receiving aspirin and then intravenous heparin, there were recurrent episodes of arterial occlusion and blindness that were immediately treated by repeated paracenteses of the anterior chamber. Visual activity again returned to 6/18 and his condition has remained stable as of his last clinic visit, 3 months after the first episode.

Aged↗
PubMed1990

Persistently raised intraocular pressure following extracapsular cataract extraction.

In this population based study we have reviewed the files of all patients who underwent an extracapsular cataract extraction (ECCE) between 1984 and 1987, were normotensives prior to surgery, and were followed up for at least 10 months after the ECCE. From a total of 1047 operations 746 qualified for the inclusion criteria; of these, 16 (2.1%) were found to have a consistently raised intraocular pressure (greater than 21 mmHg) on more than two occasions) at four months or later after surgery and throughout at least a six-month period. An increased incidence of secondary aphakic glaucoma was associated with anterior chamber IOL implantation (p less than 0.001) and posterior capsule rupture (p less than 0.01), but not with any of the other variables examined (age, sex, surgeon).

Adult↗
PubMed1990

Unusual posterior retinal holes associated with high myopia in XYY syndrome.

A 49-year-old XYY man was found to have high myopia OU with unusual multiple retinal atrophic holes located in the posterior pole, unrelated to a posterior staphyloma or any other myopic degenerative changes. Most of the retinal holes showed signs of self-healing, with no evidence of vitreous traction or retinal detachment. High myopia and atrophic retinal holes have been found in other chromosomal disorders and in one sex-chromosomal abnormality.

Fundus Oculi↗
PubMed1990

Central venous stasis retinopathy following the use of tranexamic acid.

Central venous stasis retinopathy (CVSR) was observed in two young women following the administration of oral tranexamic acid (TA) for the treatment of menorrhagia. Clinical and laboratory parameters were normal. Withdrawal of the drug and treatment with systemic steroids and fibrinolytic drugs resulted in improvement of visual acuity to 6/6. The pathogenesis of the CVSR in these cases is suggested, and the rationale of systemic treatment is discussed.

Adult↗
PubMed1988

Accommodative weakness and mydriasis following laser treatment at the peripheral retina.

Transient accommodative paresis and pupillary disturbances are some of the less known and uncommon complications of peripheral retinal laser treatment extending over at least one third of the retinal periphery. They are the result of damage by the laser applications to parasympathetic nerve fibers that lie beneath the coagulated area and innervate the ciliary body and iris sphincter. Six myopic patients who suffered from these complications following peripheral laser treatment for retinal tears are presented. A mechanism of direct damage to ciliary muscle fibers during photocoagulation is proposed.

Accommodation, Ocular↗
PubMed1988

Epidemiology of retinal vein occlusion and its association with glaucoma and increased intraocular pressure.

A population-based study found an overall incidence rate of symptomatic retinal vein occlusion (RVO) in a 4-year period to be 2.14 per 1,000 in the 40 years and over age group. When cases found among glaucoma clinic patients were separated from the remainder of the population there was marked difference in the incidence rate of RVO in the same time period (1.85 and 17.3 per 1,000, respectively). The rate of RVO increased significantly (p less than 0.001) with age in the general population from 0.93 per 1,000 among persons under 64 years of age to 5.36 per 1,000 among persons over 65. The increase in the rate of RVO by age was less dramatic in the glaucoma clinic population. The two populations also differed in the frequency of the occlusion type: the ratio of the rate of branch vein occlusion to central vein occlusion was 3.2:1 in the general population, but equally distributed in the glaucoma clinic population. Persons with increased intraocular pressure and/or glaucoma were found to have a higher prevalence of RVO than persons with no history of elevated intraocular pressure.

Adult↗