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Yafei Wu

Publications and source records attributed to Yafei Wu.

2 recordsLinked to original sources
PubMed2003

[The effect of pulsed Nd:YAG laser used as an adjunct to subgingival scaling and root planning].

OBJECTIVE: This study was to observe and compare the microbiological effects of laser therapy combined with ultrasonic subgingival scaling and root planning (SRP) versus SRP alone. METHODS: 26 contra lateral teeth were randomly assigned to the test group (laser + SRP) or the control group (SRP alone). Subgingival microbial samples were collected, cultured and analyzed at baseline, then repeated immediately after laser treatment at week 1, week 2 and week 4. RESULTS: Although both groups had significant increase in G+/G- ratio (P < 0.01), the changes of G+ and G- were more obvious in the test group till week 1(P < 0.05). The total CFU of test group diminished significantly just after laser irradiation (P < 0.05). That revealed the laser therapy followed by SRP appeared to have a stronger effect on converting the subgingival micro-ecosystem to healthy status. CONCLUSION: Laser appeared to have a stronger bactericidal action in vivo. especially on the dark-pigmented G- rods associated with periodontal disease.

Bacteria↗
PubMed2003

[A comparative study utilizing different methods for establishing an experimental periodontitis model in rats].

OBJECTIVE: To evaluate the experimental periodontitis in rats induced by ligature plus high sugar water with and without infection of periodontopathic bacteria. METHODS: Forty SD rats (5 weeks of age) were randomly divided into a control group (N) and three experimental groups (P1, P2 and P3). All experimental groups were given silk ligatures around the cervix of the second maxillary molars and were provided with drinking water containing 10% glucose. Group P2 was inoculated with P. gingivalis, three times; group P3 was inoculated with P. gingivalis and F. nucleatum, three times. At weeks 0, 2 and 4, microbiological and histological examinations were made; alveolar bone loss was stereoscopically measured as the distance from the cement-enamel junction to the alveolar crest. RESULTS: Microbiological examination indicated that the bacteria inoculated in groups P2 and P3 were successfully colonized and both of P. gingivalis and F. nucleatum were predominant among the bacterial colonies of the examined sites. At week 2, histological examination showed gingival erosion and alveolar bone loss in all experimental groups and periodontal pockets in groups P2 and P3. The most serious lesions were observed in group P3. At week 4, the periodontal destruction in all experimental groups became more severe. CONCLUSION: Ligature, high sugar water combined with mixed infection of periodontopathic bacteria can successfully induce experimental periodontitis in rats.

Animals↗