Biomedical subjects
Publications and source records attributed to Yegao Chen.
Five flavonoids were isolated from Hedyotis diffusa Willd. Their structures were elucidated as kaempferol (I), kaempferol 3-O-beta-D-glucopyranoside (II), kaempferol 3-O-(6"-O--L-rhamnosyl)-beta-D-glucopyranoside (III), quercetin 3-O-beta-D-glucopyranoside (IV) and quercetin 3-O-(2"-O-beta-D-glucopyranosyl)-beta-D-glucopyranoside (V) by spectroscopic analysis. Compounds I - III and V were originally isolated from H. diffusa.
From the fruits of Aristolochia contorta Bge, beside the known aristolochic acids IVa and VII, aristolactam-N-beta-D-glucopyanoside, aristoloctam Ia N-beta-D-glucopyanoside, pinitol and daucosterol, a new biflavonoid was isolated. Its structure was determined as (+/-)-2"R,3"R-dihydro-3"-hydroxyamentoflavone (1) by means of spectral methods including 1D-, 2D-NMR and HR-ESIMS and the known compounds were identified on the basis of comparing their NMR data with those of the corresponding compounds in the literature.
Six saponins with low sugar chain were isolated from the leaves of Panax notoginseng (Burk) F. H. Chen. Their structures were elucidated as 20(R)-ginsenoside Rh2(I), 20(R)-ginsenoside Rg3(II), ginsenoside Mc(III), ginsenoside F1(IV), ginsenoside Rh1(V) and daucosterol(VI) by spectroscopic analysis and comparison with authentic samples. Compounds I-IV were first isolated from the plant.