Biomedical subjects

Yeou Chih Wang

Publications and source records attributed to Yeou Chih Wang.

3 recordsLinked to original sources

PubMed2003

Treatment of neuroblastoma with intraspinal extensions.

Neuroblastoma is the most common malignant cause of spinal compression in the paediatric population. Chemotherapy is commonly considered as the first-line treatment for these patients. The role of neurosurgical decompression and radiotherapy are still controversial. Thirteen children diagnosed as having neuroblastoma with intraspinal extension were included in this report. All patients presented with neurological deficits and were treated with chemotherapy initially, after which 3 patients recovered, 4 improved and 6 were aggravated into paraplegia. Two of the 6 aggravated patients received emergent laminectomy with removal of intraspinal tumour and recovered satisfactorily. Although spread of tumour into the spinal canal indicates an advanced disease, aggressive treatments such as chemotherapy and surgical resection can often improve neurological symptoms and life quality. Neurological decompression is recommended for patients with intraspinal neuroblastoma and rapid neurological deterioration during chemotherapy.

Adolescent↗

PubMed2003

A modified method to perform the frameless biopsy.

Neuronavigation is increasingly being used to assist in stereotactic neurosurgery due to its frameless property. In this study, we developed and assessed a modified method of performing stereotactic brain biopsies by combining the use of the Fisher stereotactic biopsy instrument, that was fixed on universal quick-lock holder, under infrared guidance of the BrainLab VectorVision Neuronavigation system. Eighteen patients received a frameless stereotactic procedure in this study, including 5 cases of brain biopsy, 2 cases of abscess aspiration, 10 cases of hematoma aspiration and one case of Ommaya reservoir implantation. All cases were on target and successful. In this paper, we present our technique, discuss the advantage and disadvantages of the method and review the literature.

Biopsy↗

PubMed2003

Intraventricular malignant meningioma: one case report.

We report a case of primary intraventricular malignant meningioma in a 74-year-old man who presented with progressive weakness of the left limbs and dizziness, The preoperative magnetic resonance (MR) imaging of the head initially suggested that a glioblastoma multiforme or a metastatic lesion might be present. But later, the excised tumor was histologically diagnosed as a primary malignant meningioma. So far, only a few cases of intraventricular malignant meningioma have been reported. The MR imaging of this tumor has rarely been described in the literature. In the present case, the mass lesion showed hyperintensity on the T1-weighted image (T1WI) and hypointensity on the T2-weighted image (T2WI) which was not commonly seen in meningioma. The unusual MR imaging of this case may be attributed to the intratumoral hemorrhage. Although intraventricular malignant meningioma is difficult to diagnose based on MR or computed tomographic images alone, the characteristics of the MR images in the present case may offer an option for preoperative differential diagnosis of intraventricular tumors.

Aged↗