Biomedical subjects

Yi-Qun Zhang

Publications and source records attributed to Yi-Qun Zhang.

4 recordsLinked to original sources

PubMed2006

Application of needle-knife in difficult biliary cannulation for endoscopic retrograde cholangiopancreatography.

BACKGROUND: Getting directly into the common bile duct (CBD) is the most important step for successful therapeutic biliary endoscopy. In 5%-10% of cases, the CBD remains inaccessible, necessitating pre-cut papillotomy or fistulotomy with a needle-knife. The aim of this study was to assess the value of early application of the needle-knife in difficult biliary cannulation for endoscopic retrograde cholangiopancreatography (ERCP). METHODS: Patients with failed biliary cannulation after 10 minutes or guide wire entering the pancreatic tube 3 times were randomly divided into group of needle-knife cut and group of persistent cannulation by standard techniques. The cannulation times, success rates and complication rates were compared between the two groups. RESULTS: A total of 948 therapeutic biliary ERCP procedures were performed between October 2004 and February 2006. Of 91 patients with difficult biliary cannulation, 43 patients underwent needle-knife cut: the cannulation success rate was 90.7%, the mean cannulation time was 5.6 minutes, and the complication rate was 9.3%. The other 48 patients underwent persistent cannulation by standard techniques: the cannulation success rate was 75%, the mean cannulation time was 10.2 minutes, and the complication rate was 14.6%. Significant differences were observed in cannulation success rate and cannulation time but in complication rate between the two groups. CONCLUSION: The early application of the needle-knife in difficult biliary cannulation is time-saving, safe and effective, with no increase in complication rate.

Aged↗

PubMed2003

[A brief research on the life of Li Lian, the author of Yi shi (Medical history) of the Ming dynasty, and his works].

The dates of birth and death of Li Lian, a medical historian and literati of the Ming dynasty and the writing of Yi shi (Medical History) are studied. Based on the Ming scholar Chen Bo's epitaph and Li Lian's own essays and poets, Li's date of birth is settled as 1488, that of his death, 1566. Thus, the mistakes and missing of these dates of the entry "Li Lian" appeared in three biographical dictionaries are corrected. The family background of Li Lian, a descendant of the "Jin Zhong Li", a family pediatrician of over 200 years, are studied. Comprehensive analysis is made on the date of compilation of Li Lian's Medical History based on the prefaces, epitaphs of Yang Lian and Wang Ao, both Ming officials, and inferred to be around 1529 - 1530.

China↗

PubMed2003

Endoscopic biliary drainage for biliary obstruction.

OBJECTIVE: To improve the successful rate of endoscopic biliary drainage. METHODS: Three hundred and fifty-two patients with biliary obstruction were given biliary drainage via duodenoscope from January 1998 to December 2002. 258 patients received endoscopic naso-biliary drainage (ENBD), 51 endoscopic retrograde biliary drainage (ERBD), and 43 endoscopic metal biliary endoprothesis (EMBE). RESULTS: Of the 352 patients with biliary obstruction, 337 succeeded in drainage by endoscopy and 15 failed. Ten ENBD failed patients were handled successfully by readjustment of the site of the naso-biliary tube. In 3 ERBD failed patients, 2 were given plastic stents with appropriate length and got a fluent drainage. Percutaneous transhepatic biliary drainage (PTBD) was performed in one patient after failure of endoscopic management. In 2 patients with failed EMBE, one stent could not exceed the site of tumor stricture and one was obstructed by tumor implantation only one month after EMBE. Placement of another metallic stent and a plastic stent through the previous prothesis for each patient ensured a successful drainage. CONCLUSIONS: The effect of endoscopic biliary drainage for biliary obstruction is definite. Drainage failure can be avoided or remedied as early as possible by taking some active measures.

Adolescent↗

PubMed2002

Endoscopic sphincterotomy or papillary balloon dilatation for choledocholithiasis.

OBJECTIVE: To assess the safety and effect of endoscopic sphincterotomy (EST) and endoscopic papillary balloon dilatation (EPBD) for choledocholithiasis. METHODS: 328 patients with choledocholithiasis were subjected to EST or EPBD; they included 174 patients with single stone, 112 patients with two stones and 42 patients with three stones (one patient with 20 stones). Patients with stones less than 10 mm in diameter underwent EPBD and those with stones larger than 11 mm in diameter underwent EST. RESULTS: EST and EPBD succeeded in 323 patients (98.5%), and failed in 5. Stones in 98 patients were excluded spontaneously after endoscopic therapy. 207 patients were subjected to basket or balloon stone extraction. Stones in 14 patients were discharged by basket lithotripsy. Four patients were given wave lithotripsy. Stones in 22 of the 323 patients were extracted thoroughly after 2-3 times attempts. Total complications were noted in 2.5% of the patients. Hemorrhage from the gastrointestinal tract was seen in one patient, cholangitis in 4 patients, and pancreatitis in 3 patients. In 92 patients receiving digestive tract barium X-ray examination, 86 developed no barium reflux to the baliary tract, 2 pneumobilia, 4 barium reflux to the biliary tract. CONCLUSION: EST and EPBD are relatively safe and effective in treatment of choledocholithiasis, and have few complications.

Adolescent↗